ABSTRACT
The analysis of long standing morbidity of zooanthroponosis trichophytosis was carried out. The comparative laboratory analysis (microscopy, mycologic technique, polymerase chain reaction) of clinical samples from 111 patients (aged 7-14 years) with clinical diagnosis of trichophytosis (T.verrucosum), 110 patients (aged 3-14 years) with clinical diagnosis of trichophytosis (T.mentagrophytes) and 186 patients with other dermatological diseases (psoriasis, eczema) (negative control). It is demonstrated that in evaluation of diagnostic effectiveness of laboratory methods in case of mycosis induced by T.verrucosum and T.mentagrophytes the optimal choice is the examination of groups of children aged 7-14 and 3-14 years correspondingly. Under trichophytosis (T.verrucosum) sensitivity of polymerase chain reaction amounted to 98.2 (96.5-99.9)%; p<0.05, specificity - 97.5 (95.1-99.9)%; p<0.05 and diagnostic effectiveness - 97.9 (95.9-99.9)5; p<0.05. Under trichophytosis (T.mentagrophytes) sensitivity of polymerase chain reaction corresponded to 97.3 (94.8-99.8)%; p<0.05, specificity - 97.1 (94.6-99.6)%; p<0.05 and diagnostic effectiveness - 97.2 (95-99.4)5; p<0.05.
