1.
Org Lett
; 3(11): 1757-60, 2001 May 31.
Article
in English
| MEDLINE
| ID: mdl-11405704
ABSTRACT
The addition of lithium diethylphosphonate to enantiopure ketosulfinimines is highly diastereoselective (>95%), affording the first examples of quaternary alpha-alkyl alpha-amino (arylmethyl)phosphonates.
Subject(s)
Imines/chemistry , Organophosphorus Compounds/chemical synthesis , Sulfinic Acids/chemistry , Crystallography, X-Ray , Indicators and Reagents , Stereoisomerism
2.
Org Lett
; 1(7): 1053-5, 1999 Oct 07.
Article
in English
| MEDLINE
| ID: mdl-10825956
ABSTRACT
[formula: see text] 2-Methylaziridine-2-phosphonates were prepared from enantiopure sulfinimines and were demonstrated to be versatile synthetic intermediates for the synthesis of novel alpha-disubstituted and alpha,beta-trisubstituted alpha-aminophosphonate derivatives. The first asymmetric synthesis of both enantiomers of alpha-methylphosphophenylalanine is described.
