ABSTRACT
Comparative study of lipid metabolism parameters in amphipods (Gammaridae) of the White Sea infested by helminthes Podocotyle atomon (Trematoda), Levinseniella propinqua (Trematoda) and Hymenolepis microsoma (Cestoda) during different seasons was performed. It is shown that increase in the parameters of infestation induced amplification of the defense reaction of host organism, which exhibited itself by the shift in the contents of the basic membranous lipids and by the increased activity of membrane-bound enzymes, such as cytochrome P-450, at the level of the biochemical parameters examined. Since autumn increased content of phosphatidylcholine and ratio phosphatidylcholine/phosphatidylethanolamine in crustacean lipid composition was recorded. The role of phosphatidylcholine in the change of liquid-crystal state of membranes and its role as an effector of peroxidase activity of cytochrome P-450 in the amphipods infested by helminthes are discussed.