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Vopr Onkol ; 44(3): 297-9, 1998.
Article in Russian | MEDLINE | ID: mdl-9695775

ABSTRACT

Indices of lipid peroxidation in lymph from lung cancer patients before and after chemotherapy were studied. Chemotherapeutic drugs were shown to exert a moderate stressor effect on lymph by triggering oscillating reactions of endogenous antioxidant systems. Stress releases a pool of low-molecular weight antioxidants. Absence of catalase activity in plasma and lymphocytes is a peculiar feature of lymph in lung cancer patients.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/pharmacology , Free Radicals , Lipid Peroxidation/drug effects , Lung Neoplasms/metabolism , Lymph/metabolism , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Female , Humans , Lung Neoplasms/drug therapy , Male , Middle Aged
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