ABSTRACT
AIM: To characterize clinical symptoms of chronic bronchitis (CB) in Chernobyl wreckers. MATERIAL AND METHODS: 71 CB male Chernobyl wreckers exposed to low-dose radiation and 43 control patients were examined and treated in a specialized hospital in 1988-1996. Clinical features of CB were investigated by clinical (complaints, history, objective examination), laboratory (total blood count, biochemical and immunological blood picture, coagulogram) and instrumental (fibrobronchoscopy, x-ray, radiometry, spirography) findings with further statistical processing. RESULTS: Chernobyl wreckers more frequently had neurocirculatory asthenia and hemoptysis. The latter was caused by bronchial mucosa atrophy. In chronic non-obstructive bronchitis they exhibited mild bronchoobstruction on the distal level. Laboratory indices showed no essential changes. CONCLUSION: Chernobyl wreckers have a more severe course of CB.
Subject(s)
Bronchitis/etiology , Radiation Injuries/complications , Radioactive Hazard Release , Adolescent , Adult , Bronchi/pathology , Bronchi/radiation effects , Bronchitis/diagnosis , Bronchoscopy , Chronic Disease , Humans , Male , Middle Aged , Prognosis , Radiation Injuries/diagnosis , Radiography, Thoracic , Retrospective Studies , Severity of Illness Index , UkraineABSTRACT
AIM: Assessment of efficacy of combined treatment of chronic bronchitis (CB) in subjects exposed to radiation after the Chernobyl accident including nonpharmacological (NP) modalities vs conventional chemotherapy (CT). MATERIALS AND METHODS: 149 patients with different forms of CB in exacerbation were divided into 2 groups. The study group of 62 patients received NP + CT. Control group of 87 patients received CT alone. The response was judged by achievement of partial or complete remission, general condition score, external respiration function. RESULTS: The combined treatment significantly more frequently (p < 0.05) led to CB remission, more marked improvement of the patient's condition. External respiration improved insignificantly. CONCLUSION: NP in combined treatment of CB exacerbation improved the treatment results.
Subject(s)
Bronchitis/etiology , Power Plants , Radiation Injuries/etiology , Radioactive Hazard Release , Adolescent , Adrenal Cortex Hormones/administration & dosage , Adult , Aminophylline/administration & dosage , Bromhexine/administration & dosage , Bronchitis/drug therapy , Bronchitis/therapy , Bronchodilator Agents/administration & dosage , Chronic Disease , Combined Modality Therapy , Diphenhydramine/administration & dosage , Drug Therapy, Combination , Electromagnetic Fields , Expectorants/administration & dosage , Histamine H1 Antagonists/administration & dosage , Humans , Laser Therapy , Male , Middle Aged , Radiation Injuries/radiotherapy , Radiation Injuries/therapy , Time Factors , UkraineABSTRACT
Updated diagnostic and therapeutic approaches to acute pneumonia in chronic alcoholics suffering from alcoholic delirium resulted in lowering of acute pneumonia lethality in specialized medical clinics for alcoholics and drug addicts.
Subject(s)
Alcoholism/complications , Anti-Bacterial Agents/therapeutic use , Pneumonia/therapy , Acute Disease , Alcoholism/mortality , Cause of Death , Humans , Physical Therapy Modalities , Pneumonia/complications , Pneumonia/mortality , Retrospective StudiesABSTRACT
Different specific (immunological) and non-specific factors predisposing to protracted course of acute pneumonia were evaluated acute pneumonia and diagnostic errors. The course of pneumonia was protracted in 126 (48.9%) patients. Measures for prophylaxis of protracted course of pneumonia are described including increase of defensive forces of the body, biophysical and biochemical mechanisms of protection of the bronchopulmonary apparatus, removal of causes furthering slow resolution of the inflammatory process in the lungs.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Exercise Therapy , Pneumonia, Pneumococcal/prevention & control , Acute Disease , Adult , Aged , Female , Humans , Male , Middle Aged , Time FactorsSubject(s)
Pleurisy/diagnosis , Pneumonia/diagnosis , Tuberculosis, Pleural/diagnosis , Tuberculosis, Pulmonary/diagnosis , Adult , Diagnosis, Differential , Diagnostic Errors , Female , Humans , Male , Middle Aged , Mycobacterium tuberculosis/isolation & purification , Sputum/microbiology , Tuberculosis, Pleural/microbiology , Tuberculosis, Pulmonary/microbiologyABSTRACT
The paper is a review of the literature data and original clinical experience on the contribution of pathomorphosis to current diagnosis of tuberculosis and nonspecific pulmonary diseases. the analysis of 1958 case histories elucidated relevant nosological composition of the lung lesions, frequency and causes of misdiagnosis. It is believed that pathomorphosis can noticeably facilitate differential diagnosis in lung diseases even at early outpatient stage.
