ABSTRACT
Endotoxinemia was caused in rats by the lipopolysaccharide (LPS) oral application at the doses 40 mkg/kg and 200 mkg/kg. The increase of the content of triglycerides in the blood serum and in the liver was established. Besides, the LPS oral application at the dose 200 ΜΚΓ/ΚΓ the increase of the content of cholesterol in the liver was established.
Subject(s)
Cholesterol/blood , Lipid Metabolism/drug effects , Lipopolysaccharides/pharmacology , Liver/drug effects , Triglycerides/blood , Administration, Oral , Animals , Dose-Response Relationship, Drug , Liver/metabolism , Mouth Mucosa/drug effects , Mouth Mucosa/metabolism , RatsABSTRACT
With the help of scanning electronic and atomic force microscopy structure of red blood cell membranes of the system blood-groove and microcirculatory channels is studied. It is established, that in early stages of skin wounds in a peripheral blood circulation appear compressed red blood cells, losing water. As a result the basic mechanism of destruction of red blood cell membranes are interlayered shifts and stratification. In red blood cells of microvasculature, on the contrary, red blood cells in state of vacuolar degeneration are indentified. It creates preconditions for hydration and bullous deformations of membranes. Porous structures of membranes of both types erythrocytes are exposed to expansion.
Subject(s)
Cytosol/ultrastructure , Erythrocytes/chemistry , Intracellular Membranes/ultrastructure , Skin/injuries , Skin/ultrastructure , Wounds and Injuries , Dermatologic Surgical Procedures , Early Medical Intervention , Erythrocyte Membrane/ultrastructure , Humans , Microscopy, Atomic Force , Microscopy, Electron, Scanning , Specimen Handling , Wounds and Injuries/blood , Wounds and Injuries/pathology , Wounds and Injuries/surgeryABSTRACT
In the article were considered peculiarities of the estimation of damage weight to the health in conditions of ambustion affects. Also in the article was shown the actuality and practicability of elaboration of qualifying features of ambustion affects for purposes of medicolegal investigation.
Subject(s)
Burn Units , Burns/complications , Burns/physiopathology , Burns/therapy , Humans , Military Personnel , Time FactorsABSTRACT
In clause the analysis of the rendering medical help military is reflected in article with frostbites in military conflict on North Caucasus (1994-1996, 1999-2001). Efficient rendering medical help military with frostbites possible only under simultaneous observance united principle on terminological glances and provision to receivership approach to organizations of the rendering medical help damaged military. It is generalised and analysed own experience of the rendering medical help military with frostbites during military conflict on territory of the Chechen Republic (2003-2005).
Subject(s)
Frostbite/classification , Frostbite/therapy , Hospitals, Military , Military Personnel , Transportation of Patients , First Aid , Frostbite/diagnosis , Humans , Male , Military Medicine , Russia , Terrorism , WarfareABSTRACT
The article presents an analytical review of modern possibilities of the complex pathogenic treatment for severe traumas and injuries at the expense of systemic use of infusion drugs with antihypoxic and antioxidant effects. It is shown that hypoxia and oxidative stress is the typical; pathologic process that accompanies the development of traumatic disease during severe surgical pathology. One of the effective ways to correct the developing disorders is to use the regulatory or substrate antihypoxants as well as the drugs with antioxidant effect.
