[An experimental study of the early changes in the body after simultaneous radiation exposure at a low dose and stress]. / Eksperimental'noe izuchenie rannikh izmenenii v organizme posle odnovremennogo vozdeistviia radiatsii v maloi doze i stressa.

In experiments in rats it was shown that simultaneous effect of low dose radiation (12.9 cGy) and stress (immobilization) resulted in early adaptation-like changes (decrease in body weight, increase of adrenal gland weight, decrease in thymus weight, slowing down of blood coagulation). At the same time irradiation of immobilized animals prevented stressogenic disturbances such as depression of antiaggregation activity of vascular wall and decrease in leucocytes level. This was accompanied by the acceleration of mobilization of compensatory properties, that presumably is a basis for positive effects under combined influence.

[Disordered function of the vascular-thrombocyte link in the hemostatic system during tumor growth]. / Narushenie funktsii sosudisto-trombotsitarnogo zvena sistemy gemostaza v protsesse opukholevogo rosta.

The influence of tumor (RA-2) growth on the vascular-platelet haemostasis of mongrel rats was studied. The decrease of the antiaggregation properties of vascular wall and high functional activity of platelets with its intravascular aggregation were correlating with processes of tumor growth and dissemination. Anticoagulation activity of vascular wall also decreased. It is suggested that the change detected may play role in the onco-thromboembolic formation, its penetration via vascular wall and metastatic locus development.

[Effect of heparin on the vascular thrombocytic link of the hemostatic system and pathogenetic correction of ensuing disorders]. / Vliianie geparina na sosudisto-trombotsitarnoe zveno sistemy gemostaza i patogeneticheskaia korrektsiia voznikaiushchikh narushenii.

Intravenous injection of heparin (750 U/kg) induced thrombocytopenia, intravascular platelets aggregation and decreased prostacyclin-like vascular wall activity. Adverse side-effects may be prevented by injection of heparin in complex with nicotinic acid (1.5 mg/kg) and dipyridamole (2.5 mg/kg).