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Inmunología (1987) ; 32(1): 17-24, ene.-mar. 2013. ilus, tab
Article in Spanish | IBECS | ID: ibc-110481

ABSTRACT

La inmunodeficiencia variable común(IDVC) es una enfermedad heterogénea caracterizada por una disminución de los valores absolutos de los linfocitos B de memoria en la sangreperiférica.Apesardequeestadisminuciónsehaatribuidopreviamenteaunposibledefectoen el desarrollo del centro germinal, las causas permanecen en gran medida desconocidas. Por otro lado, la apoptosis (,,) (AU)


Common Variable Immunodeficiency (CVID) is a heterogeneous disease characterized by low memory B cell counts in peripheral blood (PB). Although previous reports have attributedmemoryCD27+Bcelldecrease to a possible defective germinal centre development, the cause of this defect remains basically unknown. On the other hand, increased apoptosis has been implicated in the pathogenesis of several diseases, and could be another factor that contributes (..)(AU)


Subject(s)
Humans , Apoptosis/immunology , Common Variable Immunodeficiency/immunology , B-Lymphocytes/immunology , Dactinomycin , Immunologic Tests/methods
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