Longitudinal Alterations in the Control of Lateral Center of Mass Movement During Walking in a Patient With Unilateral Transtibial Amputation: A Case Study.

This study assessed longitudinal changes in the control of the center of mass (CoM) in the lateral direction through gait reacquisition in an individual with unilateral transtibial amputation (UTTA). We examined a male patient with UTTA who could walk on a parallel bar. The marker trajectories and ground reaction forces were measured every two weeks (total: four times) using an optical motion capture system and force plates. After two measurements, the samples were collected without a parallel bar. Subsequently, we evaluated the CoM movement and its segmental coordination through uncontrolled manifold (UCM) analysis. After the second measurement, the walking speed and step length increased. The lateral CoM movements gradually increased toward the prosthetic side until the third measurement. In the fourth measurement, the CoM movement towards the prosthetic side was the smallest and closest to the intact side at the end of the stance phase. In addition, segmental coordination improved significantly. Enhanced gait performance delayed the improvement of segmental coordination for CoM movement in the lateral direction.

Sex differences in dynamic joint stiffness during walking in older adults.

BACKGROUND: Knee osteoarthritis (OA) often occurs in older women. Walking assistance such as knee brace is used to reduce mechanical stress on the knee, preventing OA onset. Dynamic joint stiffness (DJS) quantifies the resistance of an assistive device, providing a foundation for an objective bending stiffness prescription model. DJS may show sex differences among older adults. RESEARCH QUESTION: This study aimed to investigate sex differences in lower limb DJS in the sagittal plane during walking in older adults. METHODS: A total of 132 healthy older adults, aged 65 years or older (71 men and 61 women), were extracted from a public dataset. DJS of the hip, knee, and ankle joints in the sagittal plane was determined during the power absorption phase of the stance. DJS, joint angular excursion, and Δ joint moment were compared between older men and women using the Mann-Whitney U test. In addition, the r-value was calculated to represent the effect size of the differences in amplitude. RESULTS: Ankle DJS in older women was significantly lower with a reduced Δ ankle plantar flexion moment compared with that into men (p < 0.001 and p = 0.001; r = 0.35 and 0.42, respectively). Additionally, knee DJS was lower in older women (p = 0.007). However, since the joint angular excursion and ΔMoment showed no differences (p = 0.624 and 0.222, respectively), the effect size was small (r = 0.24). Hip DJS showed no significant sex differences (p = 0.703). SIGNIFICANCE: These results suggest that the decrease in ankle DJS in older women was caused by the reduced ankle plantarflexion moment. Thus, support for ankle DJS is necessary for healthy older women. Nonetheless, knee DJS does not elucidate the cause of knee OA in the older women.

Measurement of Trunk Movement during Sit-to-Stand Motion Using Laser Range Finders: A Preliminary Study.

The sit-to-stand (STS) motion evaluates physical functions in frail older adults. Mounting sensors or using a camera is necessary to measure trunk movement during STS motion. Therefore, we developed a simple measurement method by embedding laser range finders in the backrests and seats of chairs that can be used in daily life situations. The objective of this study was to validate the performance of the proposed measurement method in comparison with that of the optical motion capture (MoCap) system during STS motion. The STS motions of three healthy young adults were simultaneously measured under seven conditions using a chair with embedded sensors and the optical MoCap system. We evaluated the waveform similarity, absolute error, and relationship of the trunk joint angular excursions between these measurement methods. The experimental results indicated high waveform similarity in the trunk flexion phase regardless of STS conditions. Furthermore, a strong relationship was observed between the two measurement methods with respect to the angular excursion of the trunk flexion. Although the angular excursion of the trunk extension exhibited a large error, the developed chair with embedded sensors evaluated trunk flexion during the STS motion, which is a characteristic of frail older adults.

Effect of vibrotactile stimulation of the hallux nail on segmental coordination: A secondary analysis using uncontrolled manifold analysis.

Controlling center of mass (CoM) movement in the mediolateral direction is imperative for stable walking. During walking, CoM movement is adjusted by the coordination of each body segment, which can be evaluated using uncontrolled manifold (UCM) analysis. UCM analysis evaluates segmental coordination by analyzing variablity in motor movement among the different segments of the body. The vibrotactile stimulation of the hallux nail can augment the sensory information of the plantar surface for necessary motor control. This study aims to investigate the effect of the vibrotactile stimulation of the hallux nail on segmental coordination to control CoM movement in the mediolateral direction during walking. Thirteen healthy men participated in the study. A vibrator was attached to each hallux nail, and pressure sensors were placed under the hallux balls. When the hallux ball was in contact with the floor, vibration stimulation was applied. A three-dimensional motion analysis system was used to measure the segment angles during walking, and UCM analysis was used to evaluate kinematic synergy for controlling CoM movement in the mediolateral direction. Subsequently, segment angles were used as an elemental variable. The synergy index and bad variability as motor noise were negatively related to the status without the stimulation. Vibrotactile stimulation in young people was more effective for people with large motor noise and a small synergy index during the single-stance phase. Thus, kinematic synergy can be immediately changed by sensory input using vibrotactile stimulation of the hallux nail, although applying vibration stimulation should be considered in advance.

Effects of age and gender on spatiotemporal and kinematic gait parameters in older adults.

PURPOSE: Gait changes are more prominently observed in older adults than in young adults, especially in kinematics of lower extremities and trunk. These changes can result in incidental falls during gait, possibly leading to inability to perform activities of daily living independently. This study aimed to investigate the effect of gender and age on gait changes, such as spatiotemporal parameters and peak joint angles in lower extremities and trunk during gait. METHODS: A total of 387 participants (223 women) were included. The Microsoft Kinect V2 sensor was used to obtain the coordinate data of lower extremities and trunk during gait. The coordinate data obtained were processed using the software. Walking speed, stride length, stride time and cadence were calculated as spatiotemporal variables of walking. Forward trunk tilt angle (FTT), hip flexion and extension, and knee flexion and extension were measured as peak angles during one-gait cycle. Participants were categorized into five groups according to age by five years. Multivariate analysis of variance was performed to compare the spatiotemporal and kinematical data among groups. RESULTS: Significant differences among age groups were noted in terms of the walking speed and stride length. Significant differences were also observed in the FTT and hip extension angle. CONCLUSIONS: Increased gait changes, increased peak FTT and decreased peak hip extension angle were observed with an increase of age. These altered symptoms may contribute to the screening of older adults at risk of declined physical function at an early stage.

Digital Twin-Driven Human Robot Collaboration Using a Digital Human.

Advances are being made in applying digital twin (DT) and human-robot collaboration (HRC) to industrial fields for safe, effective, and flexible manufacturing. Using a DT for human modeling and simulation enables ergonomic assessment during working. In this study, a DT-driven HRC system was developed that measures the motions of a worker and simulates the working progress and physical load based on digital human (DH) technology. The proposed system contains virtual robot, DH, and production management modules that are integrated seamlessly via wireless communication. The virtual robot module contains the robot operating system and enables real-time control of the robot based on simulations in a virtual environment. The DH module measures and simulates the worker's motion, behavior, and physical load. The production management module performs dynamic scheduling based on the predicted working progress under ergonomic constraints. The proposed system was applied to a parts-picking scenario, and its effectiveness was evaluated in terms of work monitoring, progress prediction, dynamic scheduling, and ergonomic assessment. This study demonstrates a proof-of-concept for introducing DH technology into DT-driven HRC for human-centered production systems.

Self-Reported Walking Difficulty Associated with Stiff-Knee Gait in Japanese Patients with Knee Osteoarthritis: A Preliminary Cross-Sectional Study.

BACKGROUND: Individuals with knee osteoarthritis are restricted in their daily activity because of walking difficulty. The purpose of this investigation was to examine the association between self-reported walking difficulty and knee flexion excursion during gait in Japanese patients with knee osteoarthritis. METHODS: Twenty-eight patients with knee osteoarthritis participated in this study. Knee flexion excursions in loading response and swing during gait were measured through an inertial measurement unit-based motion capture system. The walking difficulty was assessed by a subitem in the Japanese Knee Osteoarthritis Measure. Pain intensity was assessed by a visual analog scale. Characteristics and gait variables were compared between groups that were determined a priori using the results of the walking difficulty assessment. The relationship between knee flexion excursion during gait and walking difficulty were analyzed using logistic regression. RESULTS: The participants with walking difficulty had significantly small knee flexion excursion in both loading response and swing with large pain. After controlling the effect of pain, only knee flexion excursion in the swing was significantly related to the walking difficulty. CONCLUSIONS: This study suggested that the knee flexion excursion in swing during gait is helpful for understanding the walking difficulty experienced in Japanese patients with knee osteoarthritis.

Self-Perception of the Knee Is Associated with Joint Motion during the Loading Response in Individuals with Knee Osteoarthritis: A Pilot Cross-Sectional Study.

Small knee flexion motion is a characteristic of gait in individuals with knee osteoarthritis. This study examined the relationship between knee flexion excursion in loading response and knee self-perception in individuals with knee osteoarthritis. Twenty-one individuals with knee osteoarthritis participated in this study. Knee flexion excursions in loading response while walking at a comfortable and a fast-walking speed were measured using an inertial measurement unit-based motion capture system. The degree of knee perceptual impairment was evaluated using the Fremantle Knee Awareness Questionnaire (FreKAQ). The relationships between the FreKAQ score and gait variables and knee function were evaluated by calculating the correlation coefficient. The unique contributions of knee self-perception and muscle strength to knee flexion excursion in loading response were analyzed using hierarchical linear regression. Knee self-perception was significantly correlated with pain during walking, muscle strength and knee flexion excursion at fast speed. In the fast speed condition only, impaired knee self-perception was inversely proportional to knee flexion excursion and accounted for 21.8% of the variance in knee flexion excursion. This result suggests that impaired self-perception of the knee may help to explain the decrease in the knee flexion excursion in the loading response in individuals with knee osteoarthritis.

Comparison of Supervised Machine Learning Algorithms for Classifying of Home Discharge Possibility in Convalescent Stroke Patients: A Secondary Analysis.

OBJECTIVES: Classifying the possibility of home discharge is important during stroke rehabilitation to support decision-making. There have been several studies on supervised machine learning algorithms, but only a few have compared the performance of different algorithms based on the same dataset for the classification of home discharge possibility. Therefore, we aimed to evaluate five supervised machine learning algorithms for the classification of home discharge possibility in stroke patients. MATERIALS AND METHODS: This was a secondary analysis based on the data of 481 stroke patients from the database of our institution. Five models developed by supervised machine learning algorithms, including decision tree (DT), linear discriminant analysis (LDA), k-nearest neighbors (k-NN), support vector machine (SVM), and random forest (RF) were compared by constructing a classification system based on the same dataset. Several parameters including classification accuracy, area under the curve (AUC), and F1 score (a weighted average of precision and recall) were used for model evaluation. RESULTS: The k-NN model had the best classification accuracy (84.0%) with a moderate AUC (0.88) and F1 score (87.8). The SVM model also showed high classification accuracy (82.6%) along with the highest AUC (0.91), sensitivity (94.4), negative predictive value (87.5), and negative likelihood ratio (0.088). The DT, LDA, and RF models had high classification accuracies (≥ 79.9%) with moderate AUCs (≥ 0.84) and F1 scores (≥ 83.8). CONCLUSIONS: Regarding model performance, the k-NN and SVM seemed the best candidate algorithms for classifying the possibility of home discharge in stroke patients.

Decision Tree Algorithm Identifies Stroke Patients Likely Discharge Home After Rehabilitation Using Functional and Environmental Predictors.

BACKGROUND AND PURPOSE: The importance of environmental factors for stroke patients to achieve home discharge was not scientifically proven. There are limited studies on the application of the decision tree algorithm with various functional and environmental variables to identify stroke patients with a high possibility of home discharge. The present study aimed to identify the factors, including functional and environmental factors, affecting home discharge after stroke inpatient rehabilitation using the machine learning method. METHOD: This was a cohort study on data from the maintained database of all patients with stroke who were admitted to the convalescence rehabilitation ward of our facility. In total, 1125 stroke patients were investigated. We developed three classification and regression tree (CART) models to identify the possibility of home discharge after inpatient rehabilitation. RESULTS: Among three models, CART model incorporating basic information, functional factor, and environmental factor variables achieved the highest accuracy for identification of home discharge. This model identified FIM dressing of the upper body (score of ≤2 or >2) as the first single discriminator for home discharge. Performing house renovation was associated with a high possibility of home discharge even in patients with stroke who had a poor FIM score in the ability to dress the upper body (≤2) at admission into the convalescence rehabilitation ward. Interestingly, many patients who performed house renovation have achieved home discharge regardless of the degree of lower limb paralysis. CONCLUSION: We identified the influential factors for realizing home discharge using the decision tree algorithm, including environmental factors, in patients with convalescent stroke.

Indoor vs. Outdoor Walking: Does It Make Any Difference in Joint Angle Depending on Road Surface?

Measurement of the joint angle during walking in real-world environments facilitates comprehension of the adaptation strategy corresponding to road surfaces. This study investigated the differences between the joint angles in the lower limb when walking on flat road surfaces in indoor and outdoor environments. Ten healthy young males who walked on a carpet-lined corridor in the indoor environment and on an interlocking block pavement surface in the outdoor environment participated in the study. The joint angles of their lower limbs were measured using seven inertial measurement units, and the average and coefficient of variation (%CV) of the joint angular excursion in the two environments were evaluated. The %CVs of the ankle plantar flexion excursion in the early stance was 45% higher in the outdoor environment compared with that in the indoor, although the spatiotemporal parameters and joint angular excursion of the proximal joints showed no difference between the environments. Though the road surfaces were flat from a macroscopic point of view, the interlocking block pavement had stiffer and more irregular characteristics. The variability in the ankle plantar flexion motion in the early stance may be most likely affected by these surface characteristics in the real-world outdoor environment.

Analysis of walking variability through simultaneous evaluation of the head, lumbar, and lower-extremity acceleration in healthy youth.

[Purpose] The purpose of this study was to clarify whether walking speed affects acceleration variability of the head, lumbar, and lower extremity by simultaneously evaluating of acceleration. [Subjects and Methods] Twenty young individuals recruited from among the staff at Kurashiki Heisei Hospital participated in this study. Eight accelerometers were used to measure the head, lumbar and lower extremity accelerations. The participants were instructed to walk at five walking speeds prescribed by a metronome. Acceleration variability was assessed by a cross-correlation analysis normalized using z-transform in order to evaluate stride-to-stride variability. [Results] Vertical acceleration variability was the smallest in all body parts, and walking speed effect had laterality. Antero-posterior acceleration variability was significantly associated with walking speed at sites other than the head. Medio-lateral acceleration variability of the bilateral hip alone was smaller than the antero-posterior variability. [Conclusion] The findings of this study suggest that the effect of walking speed changes on the stride-to-stride acceleration variability was individual for each body parts, and differs among directions.

Age-related differences in muscle control of the lower extremity for support and propulsion during walking.

[Purpose] This study examined age-related differences in muscle control for support and propulsion during walking in both males and females in order to develop optimal exercise regimens for muscle control. [Subjects and Methods] Twenty elderly people and 20 young people participated in this study. Coordinates of anatomical landmarks and ground reaction force during walking were obtained using a 3D motion analysis system and force plates. Muscle forces during walking were estimated using OpenSim. Muscle modules were obtained by using non-negative matrix factorization analysis. A two-way analysis of covariance was performed to examine the difference between the elderly and the young in muscle weightings using walking speed as a covariate. The similarities in activation timing profiles between the elderly and the young were analyzed by cross-correlation analysis in males and females. [Results] In the elderly, there was a change in the coordination of muscles around the ankle, and muscles of the lower extremity exhibited co-contraction in late stance. Timing and shape of these modules were similar between elderly and young people. [Conclusion] Our results suggested that age-related alteration of muscle control was associated with support and propulsion during walking.

Age and gender differences in the control of vertical ground reaction force by the hip, knee and ankle joints.

[Purpose] This study examined the relationships between joint moment and the control of the vertical ground reaction force during walking in the elderly and young male and female individuals. [Subjects and Methods] Forty elderly people, 65 years old or older (20 males and 20 females), and 40 young people, 20 to 29 years old (20 males and 20 females), participated in this study. Joint moment and vertical ground reaction force during walking were obtained using a 3D motion analysis system and force plates. Stepwise linear regression analysis determined the joint moments that predict the amplitude of the vertical ground reaction force. [Results] Knee extension moment was related to the vertical ground reaction force in the young males and females. On the other hand, in the elderly females, hip, ankle, and knee joint moments were related to the first peak and second peak forces, and the minimum value of vertical ground reaction force, respectively. [Conclusion] Our results suggest that the young males and females make use of the knee joint moment to control of the vertical ground reaction force. There were differences between the elderly and the young females with regard to the joints used for the control of the vertical ground reaction force.