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1.
Br J Neurosurg ; 33(6): 684-686, 2019 Dec.
Article in English | MEDLINE | ID: mdl-29160114

ABSTRACT

Brown tumours affecting the cervical spine are a rare but recognised complication of renal failure-related secondary hyperparathyroidism. We present a case of a 26 year-old female with radiculopathy who was managed successfully with 360° cervical spine fixation and parathyroidectomy.


Subject(s)
Cervical Vertebrae/surgery , Hyperparathyroidism, Secondary/complications , Osteitis Fibrosa Cystica/surgery , Spinal Neoplasms/surgery , Adult , Female , Humans , Hyperparathyroidism, Secondary/surgery , Osteitis Fibrosa Cystica/complications , Parathyroidectomy/methods , Radiculopathy/etiology , Radiculopathy/surgery , Spinal Neoplasms/complications
2.
BMJ Case Rep ; 20142014 Nov 13.
Article in English | MEDLINE | ID: mdl-25395468

ABSTRACT

Scleroderma renal crisis (SRC) is a major complication of systemic sclerosis (SSc). We present a case of a patient who died of complications attributable to SRC in the context of recently diagnosed SSc. We review the typical clinical and laboratory features of SSc present in our patient and highlight those that identify greater risk of progression to SRC. Particular risk factors for SRC include cutaneous involvement, positive anti-RNA polymerase III antibodies and use of corticosteroids (CS). The authors emphasise the importance of risk evaluation when choosing to use CS in patients with SSc.


Subject(s)
Acute Kidney Injury/etiology , Glucocorticoids/adverse effects , Prednisolone/adverse effects , Scleroderma, Systemic/complications , Aged , Antibodies, Antinuclear/blood , DNA Topoisomerases, Type I , Fatal Outcome , Glomerular Filtration Rate , Humans , Hypertension/etiology , Male , Nuclear Proteins/immunology , Risk Factors
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