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J Urol ; 159(6): 1833-5, 1998 Jun.
Article in English | MEDLINE | ID: mdl-9598470

ABSTRACT

PURPOSE: We determine if post-chemotherapy resection of residual retroperitoneal and chest tumor under the same anesthetic is reasonable based on tumor pathology and morbidity, and if the finding of necrosis in the abdomen allows observation of chest tumor. MATERIALS AND METHODS: We retrospectively reviewed 143 post-chemotherapy patients who underwent resection of residual retroperitoneal and chest disease under the same anesthetic. RESULTS: Retroperitoneal pathology was generally predictive of chest pathology. Concordance existed in 77.5% of patients with necrosis, 70% with teratoma and 69% with cancer of the abdomen. However, the correlation was much stronger (86%) in predicting necrosis/fibrosis if cases were categorized as uncomplicated by Indiana University criteria. Although the morbidity of the combined approach is higher than that of standard post-chemotherapy retroperitoneal lymph node dissection, it was acceptable. CONCLUSIONS: The morbidity of post-chemotherapy retroperitoneal lymph node dissection and resection of chest disease under the same anesthetic is acceptable. Retroperitoneal pathology generally predicts chest pathology but this correlation is much stronger if the case is uncomplicated based on our criteria. In an uncomplicated case the discovery of necrosis of the abdomen allows observation of chest tumor.


Subject(s)
Anesthesia , Lymph Node Excision , Retroperitoneal Neoplasms/surgery , Thoracic Neoplasms/surgery , Thoracic Surgical Procedures , Antineoplastic Agents/therapeutic use , Fibrosis , Humans , Male , Morbidity , Necrosis , Neoplasm, Residual , Retroperitoneal Neoplasms/drug therapy , Retroperitoneal Neoplasms/pathology , Retroperitoneal Neoplasms/secondary , Retrospective Studies , Testicular Neoplasms/drug therapy , Testicular Neoplasms/pathology , Thoracic Neoplasms/drug therapy , Thoracic Neoplasms/pathology , Thoracic Neoplasms/secondary
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