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1.

[Antiviral compounds. XIV. Activities of alkoxy-acetophenones and -benzalacetones N-substituted amidinohydrazones].

Toku, H; Nishimura, T; Fukuyasu, H; Kazuno, Y.

Yakugaku Zasshi ; 104(8): 903-8, 1984 Aug.

Article in Japanese | MEDLINE | ID: mdl-6520716

Subject(s)

Acetophenones/pharmacology , Hydrazones/pharmacology , Influenza A virus/drug effects , Ketones/pharmacology , Bacteria/drug effects , Drug Resistance, Microbial , Fungi/drug effects , Structure-Activity Relationship

2.

[Antimicrobial activities of N-arylsulfonylthioureas].

Toku, H; Nishimura, T; Fukuyasu, H; Fukuyasu, T; Kazuno, Y.

Yakugaku Zasshi ; 103(2): 209-12, 1983 Feb.

Article in Japanese | MEDLINE | ID: mdl-6408239

Subject(s)

Bacteria/drug effects , Fungi/drug effects , Sulfonylurea Compounds/pharmacology , Thiourea/analogs & derivatives , Drug Evaluation, Preclinical , Drug Resistance, Microbial , Influenza A virus/drug effects , Mycoplasma/drug effects , Structure-Activity Relationship , Thiourea/pharmacology

3.

Antiviral compounds. XIII. Synthesis and anti-influenza virus activity of N-(1-adamantyl)amidinohydrazones.

Nishimura, T; Toku, H; Fukuyasu, H; Kawakami, M; Kazuno, Y; Sekizawa, Y.

Kitasato Arch Exp Med ; 52(1-4): 15-21, 1979 Dec.

Article in English | MEDLINE | ID: mdl-261989

Subject(s)

Adamantane/analogs & derivatives , Influenza A virus/drug effects , Adamantane/chemical synthesis , Adamantane/pharmacology , Adamantane/toxicity , Animals , Drug Resistance, Microbial , Hydrazones/chemical synthesis , Hydrazones/pharmacology , Hydrazones/toxicity , Mice , Structure-Activity Relationship

4.

Antiviral compounds. XI. Synthesis and anti-influenza virus activity of alkoxy-phenyl- and styryl-glyoxal bis-amidinohydrazones.

Nishimura, T; Toku, H; Yamazaki, C; Hasegawa, K; Nagaki, D.

Kitasato Arch Exp Med ; 50(1-2): 31-8, 1977 Jun.

Article in English | MEDLINE | ID: mdl-616472

Subject(s)

Antiviral Agents/chemical synthesis , Hydrazones/chemical synthesis , Orthomyxoviridae/drug effects , Antiviral Agents/analysis , Glyoxal/analogs & derivatives , Glyoxal/chemical synthesis , Hydrazones/analysis

5.

Antiviral compounds. XII. Antiviral activity of amidinohydrazones of alkoxyphenyl-substituted carbonyl compounds against influenza virus in eggs and in mice.

Nishimura, T; Toku, H; Fukuyasu, H.

Kitasato Arch Exp Med ; 50(1-2): 39-46, 1977 Jun.

Article in English | MEDLINE | ID: mdl-616473

Subject(s)

Antiviral Agents/pharmacology , Hydrazones/pharmacology , Orthomyxoviridae Infections/drug therapy , Orthomyxoviridae/drug effects , Animals , Antiviral Agents/therapeutic use , Drug Evaluation, Preclinical , Hydrazones/therapeutic use , Ketones/pharmacology , Ketones/therapeutic use , Mice , Virus Replication/drug effects

6.

[Antimycoplasmal compounds. II. Antimycoplasmal activity of bis-thiosemicarbazones (author's transl)].

Nishimura, T; Toku, H; Fukuyasu, T; Yusa, Y; Sekizawa, Y.

Yakugaku Zasshi ; 97(6): 671-5, 1977 Jun.

Article in Japanese | MEDLINE | ID: mdl-925859

Subject(s)

Mycoplasma/drug effects , Semicarbazones/pharmacology , Animals , Chick Embryo

7.

Antiviral compounds. IX. Synthesis and anti-influenza virus activity of bis-amidinohydrazones of glyoxal and methylglyoxal.

Nishimura, T; Toku, H; Yamazaki, C; Hasegawa, K; Sakaguchi, H; Nagaki, D.

Kitasato Arch Exp Med ; 48(4): 171-81, 1975 Dec.

Article in English | MEDLINE | ID: mdl-1234925

Subject(s)

Antiviral Agents/pharmacology , Guanidines/pharmacology , Influenza A virus/drug effects , Antiviral Agents/chemical synthesis , Biguanides/chemical synthesis , Biguanides/pharmacology , Glyoxal/analogs & derivatives , Guanidines/chemical synthesis , Mitoguazone/pharmacology , Pyruvaldehyde/analogs & derivatives

8.

Antiviral compounds. VIII. Synthesis and anti-influenza virus activity of amidinohydroazones of alkoxybenzaldehydes and alkoxycinnamaldehydes.

Nishimura, T; Yoshii, S; Toku, H; Hasegawa, K; Nagaki, D.

Kitasato Arch Exp Med ; 48(4): 165-70, 1975 Dec.

Article in English | MEDLINE | ID: mdl-1234924

Subject(s)

Antiviral Agents/pharmacology , Hydrazones/pharmacology , Influenza A virus/drug effects , Amidines/chemical synthesis , Amidines/pharmacology , Antiviral Agents/chemical synthesis , Benzaldehydes/chemical synthesis , Benzaldehydes/pharmacology , Chemical Phenomena , Chemistry , Hydrazones/chemical synthesis

9.

Antiviral compounds. VII. Synthesis and anti-influenza virus activity of alkoxyacetophenone amidinohydrazones.

Nishimura, T; Toku, H; Yoshii, S; Hasegawa, K; Nagaki, D.

Kitasato Arch Exp Med ; 48(2-3): 125-30, 1975 Sep.

Article in English | MEDLINE | ID: mdl-1232479

Subject(s)

Antiviral Agents , Influenza A virus/drug effects , Orthomyxoviridae/drug effects , Acetophenones/pharmacology , Antiviral Agents/chemical synthesis , Chemical Phenomena , Chemistry , Humans , Hydrazones/chemical synthesis , In Vitro Techniques , Microbial Sensitivity Tests , Structure-Activity Relationship

10.

Antiviral compounds. V. Synthesis and anti-influenza virus activity of amidinohydrazones of aliphatic monocarbonyl compounds.

Toku, H; Nishimura, T; Hasegawa, K; Nagaki, D.

Kitasato Arch Exp Med ; 48(1): 19-22, 1975 Mar.

Article in English | MEDLINE | ID: mdl-1195575

Subject(s)

Hydrazones/chemical synthesis , Orthomyxoviridae/drug effects , Amidines/chemical synthesis , Amidines/pharmacology , Antiviral Agents/chemical synthesis , Hydrazones/pharmacology

11.

Antiviral compounds. VI. Synthesis and anti-influenza virus activity of alkoxybenzalacetone amidinohydrazones.

Nishimura, T; Yoshii, S; Toku, H; Hasegawa, K; Nagaki, D.

Kitasato Arch Exp Med ; 48(1): 23-30, 1975 Mar.

Article in English | MEDLINE | ID: mdl-1195576

Subject(s)

Hydrazones/chemical synthesis , Orthomyxoviridae/drug effects , Amidines/chemical synthesis , Amidines/pharmacology , Antiviral Agents/chemical synthesis , Hydrazones/pharmacology

12.

Antiviral compounds. IV. Synthesis and anti-influenza virus activity of amidinohydrazones.

Nishimura, T; Yamazaki, C; Toku, H; Yoshii, S; Hasegawa, K.

Chem Pharm Bull (Tokyo) ; 22(10): 2444-7, 1974 Oct.

Article in English | MEDLINE | ID: mdl-4468091

Subject(s)

Amidines/pharmacology , Orthomyxoviridae/drug effects , Amidines/chemical synthesis , Antiviral Agents/pharmacology , Hydrazones/chemical synthesis , Hydrazones/pharmacology

13.

Preparation of 1-amino-3-methylguanidine acid salts.

Toku, H; Koyama, S; Nishimura, T.

Kitasato Arch Exp Med ; 46(3-4): 125-30, 1973 Dec.

Article in English | MEDLINE | ID: mdl-4805360

Subject(s)

Guanidines/chemical synthesis , Methylguanidine/chemical synthesis , Amines/chemical synthesis , Chemical Phenomena , Chemistry , Cyanates , Hydrazones/chemical synthesis , Methylguanidine/analysis

14.

[Antibacterial activities of amidinohydrazones. I. Antibacterial activities of alkoxybenzalacetone amidinohydrazones (author's transl)].

Nishimura, T; Yoshii, S; Toku, H; Mochizuki, H.

Yakugaku Zasshi ; 93(9): 1236-42, 1973 Sep.

Article in Japanese | MEDLINE | ID: mdl-4797585

Subject(s)

Amidines/pharmacology , Bacteria/drug effects , Hydrazones/pharmacology , Fungi/drug effects , Phenyl Ethers/pharmacology , Structure-Activity Relationship

15.

[Antibacterial activities of amidinohydrazones. II. Antibacterial activities of alkoxyacetophenone amidinohydrazones (author's transl)].

Nishimura, T; Toku, H; Yoshi, S; Morishige, M.

Yakugaku Zasshi ; 93(9): 1242-6, 1973 Sep.

Article in Japanese | MEDLINE | ID: mdl-4797586

Subject(s)

Amidines/pharmacology , Bacteria/drug effects , Hydrazones/pharmacology , Phenyl Ethers/pharmacology , Structure-Activity Relationship

16.

[Antibacterial activities of amidinohydrazones. 3. Antibacterial activities of alkoxybenzaldehyde and cinnamaldehyde amidinohydrazones (author's transl)].

Nishimura, T; Yoshi, S; Toku, H; Watanabe, M.

Yakugaku Zasshi ; 93(9): 1247-50, 1973 Sep.

Article in Japanese | MEDLINE | ID: mdl-4797587

Subject(s)

Amidines/pharmacology , Bacteria/drug effects , Hydrazones/pharmacology , Phenyl Ethers/pharmacology , Structure-Activity Relationship

17.

Antibacterial activities of amidinohydrazones of benzalacetones, cinnamaldehydes, acetophenones and benzaldehydes.

Nishimura, T; Yoshii, S; Toku, H; Mochizuki, H.

Kitasato Arch Exp Med ; 46(1): 73-81, 1973 Jun.

Article in English | MEDLINE | ID: mdl-4793871

Subject(s)

Bacteria/drug effects , Hydrazones/pharmacology , Acetophenones/pharmacology , Aldehydes/pharmacology , Anti-Bacterial Agents/pharmacology , Benzaldehydes/pharmacology

18.

Synthesis of guanidines.

Toku, H; Sakabe, Y; Mogi, S; Nishimura, T.

Kitasato Arch Exp Med ; 44(3): 213-22, 1971 Dec.

Article in English | MEDLINE | ID: mdl-5155557

Subject(s)

Guanidines/chemical synthesis , Amines , Thiourea

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