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1.
Gan To Kagaku Ryoho ; 47(11): 1627-1629, 2020 Nov.
Article in Japanese | MEDLINE | ID: mdl-33268742

ABSTRACT

We report a case of early gastric cancer in the remnant stomach after successful treatment with endoscopic submucosal dissection(ESD). A 64-year-old woman had undergone distal gastrectomy, D2 dissection, and Billroth Ⅰ reconstruction for advanced gastric cancer 11 years previously. During a routine upper gastrointestinal endoscopy, an elevated lesion was detected at the lesser curvature of the upper gastric body of the remnant stomach, and biopsy indicated a Group 4 tumor. Curative en bloc resection of the lesion was achieved via ESD, although there was severe fibrosis along the suture line. The pathological result was 0-I, pT1a, tub1, 3×3 mm, UL(-), ly(-), v(-), HM0(8 mm), VM0(800 µm), indicating curative resection. Surveillance of the upper gastrointestinal tract 5 years after gastric cancer surgery enabled the early detection of the gastric cancer and curative resection with ESD.


Subject(s)
Gastric Stump , Stomach Neoplasms , Female , Gastrectomy , Gastric Mucosa , Gastric Stump/surgery , Humans , Middle Aged , Retrospective Studies , Stomach Neoplasms/surgery , Treatment Outcome
2.
Gan To Kagaku Ryoho ; 47(1): 159-161, 2020 Jan.
Article in Japanese | MEDLINE | ID: mdl-32381891

ABSTRACT

Here, we report a case of superficial-type gastric cancer with metastatic ovarian cancer(Krukenberg tumor)diagnosed by exploratory laparotomy. Chemotherapy was initiated at an early stage in this patient. A 43-year-old woman with superficialtype gastric cancer(0-Ⅱb plusⅡa), an ovarian tumor, and a solitary sclerotic bone lesion underwent exploratory laparotomy and bilateral salpingo-oophorectomy. Pathological findings showed that the resected ovarian tumor specimen contained the same type of signet ring cell carcinoma as the biopsy gastric cancer specimen; hence, the patient was diagnosed with superficial- type gastric cancer with metastatic ovarian cancer. She was treated with first-line chemotherapy(capecitabine plus oxaliplatin)15 days after exploratory laparotomy, followed by second-line chemotherapy(ramucirumab plus paclitaxel), thirdline chemotherapy(nivolumab), and fourth-line chemotherapy(irinotecan). Twenty-two months after the start of first-line chemotherapy, she finally died due to bone metastasis.


Subject(s)
Carcinoma, Signet Ring Cell , Ovarian Neoplasms , Stomach Neoplasms , Adult , Carcinoma, Signet Ring Cell/secondary , Female , Humans , Laparotomy , Ovarian Neoplasms/secondary
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