Videoconferencias para residentes de Histología en la Universidad de Ciencias Médicas de Sancti Spíritus

Fundamento: No se conoce cómo aceptan los residentes de Histología la inclusión de un sistema de videoconferencias sobre la estructura microscópica del cuerpo humano en su estrategia de autoaprendizaje.Objetivo: Explorar en profundidad la experiencia de los residentes de Histología de la Universidad de Ciencias Médicas de Sancti Spíritus que utilizaron un sistema de videoconferencias para su formación profesional.Metodología: Estudio cualitativo en el que se realizó una entrevista a profundidad con los especialistas y residentes de Histología que han utilizado el sistema de videoconferencias en la Universidad de Ciencias Médicas de Sancti Spíritus. Se transcribieron las entrevistas, se codificaron y se seleccionaron los principales temas abordados.Resultados: Se entrevistaron 5 usuarios del sistema de videoconferencias; de la entrevista surgieron 5 temas: 1) Como los residentes insertan las videoconferencias en su estrategia de autoaprendizaje, 2) Preferencia de las videoconferencias sobre los libros de texto, 3) Aciertos y desaciertos de las videoconferencias, 4) ¿Qué aportan las videoconferencias a la formación del residente, ventajas y desventajas? y 5) Sugerencias para mejorar las videoconferencias.Conclusiones: Un sistema de videoconferencias sobre la estructura microscópica del cuerpo humano puede ocupar un papel protagónico en la estrategia de aprendizaje de residentes de Histología. La preferencia que muestran los residentes por las videoconferencias sobre otros medios didácticos puede estar asociada a la capacidad de la multimedia para disminuir la carga cognitiva y facilitar el aprendizaje cuando se siguen los principios de Mayer al elaborar estos medios. La presencia de imágenes digitales en estas videoconferencias fue clave para su aceptación. [AU]

Large Corpora and Historical Syntax: Consequences for the Study of Morphosyntactic Diffusion in the History of Spanish.

Over the turn of the 21st century, the use of data from large electronic corpora has changed research on Spanish historical syntax, spurring interest in long-range evolutions, and the shape of the correspondent diachronic curves. However, general reflections on diffusion and the factors that drive and influence it are still pretty much lacking. In this paper, I reflect on the research possibilities laid open by the availability of such large masses of data, focusing particularly on new knowledge on syntactic change brought about by the study of low-frequency phenomena and of recessive changes, as well as on the exploration of changes conditioned by dialect contact, and textual traditions. I conclude with some remarks on the general typology of diffusion in syntactic change.

Impacto de la salud bucal sobre la calidad de vida de los niños de 11 a 14 años de tres escuelas nacionales de Asunción / Impact of oral health on the quality of life of children from 11 to 14 years of taking three National Schools from Asunción

INTRODUCCIÓN: La cavidad bucal no es solo una parte importante de nuestro sistema digestivo, es un lugar cargado de emociones desde el inicio de la vida. Todas las personas deberían contar con una salud bucal que permita cumplir con sus funciones físicas y emocionales. La calidad de vida y la salud bucal están estrechamente relacionadas. OBJETIVO: Conocer el impacto de la salud bucal de los niños de 11 a 14 años de tres Escuelas Nacionales de Asunción en su calidad de vida. MATERIAL Y MÉTODOS: Estudio observacional, descriptivo y de corte transverso. Realizado en niños (n=133) de tres escuelas nacionales de Asunción en el año 2016, donde se utilizó el cuestionario de autopercepción (CPQ 11-14) del impacto de las condiciones bucales en su versión corta en español. Los datos fueron procesados en el programa Excel. RESULTADOS: El 63% de los encuestados tiene una autopercepción de Regular en cuanto a la salud de sus dientes. El 37% respondió haber tenido problemas en sus actividades diarias por causa de sus dientes. El 43% manifestó tener Sintomatología oral (empaquetamiento dentario 67,2%, dolor dentario (50,4%), sangrado en las encías (48,6%) y problemas para dormir por dolor (28%), el 26% reportó una Limitación funcional. La hipersensibilidad fue la limitación con mayor frecuencia (53%), seguido por problemas para comer cosas duras (28%). El 18% presentó afección en el Bienestar emocional y el 10% en el ámbito Bienestar social. En la evaluación de necesidad de salud bucal percibida se concluyó que los encuestados necesitan asistir al dentista para una evaluación, pues existe impacto físico y emocional en la calidad de vida de los encuestados.

INTRODUCTION: The oral cavity is not only an important part of our digestive system, is a place full of emotions from the beginning of life. Every ones hould have an oral health that can effectively meet their physical and emotional functions. Quality of life and oral health are closely related. OBJECTIVE: Tok now the impact of oral health of children from 11 to 14 years of three national schools of Asuncion in their quality of life. METHODS: Observational, descriptive and transverse sectional study. Involving children (n = 133) of three National Schools of Asunción in 2016, where the self-perception questionnaire (CPQ 11-14) the impact of oral conditions in its short version in spanish was used. The data were processed in the Excel program. RESULTS: 63% of respondent shave a self-perception Regular regarding the health of your teeth. 37% of respondent shave had problems in their daily activities because of their teeth. 43% reported Oral symptoms (67.2%), packaging tooth toothache (50.4%), bleeding gums (48.6%) and pain trouble sleeping (28%), 26% reported a Functional limitation. The hypersensitivity was limited more often (53%), followed by trouble eating hard (28%) things. the 18% presented condition in the emotional well being and 10% in the field Social welfare in assessing perceived need for oral health was concluded that respondents need to attend to the dentist for an evaluation, as there is physical and emotional impact on the quality of life of respondents.

Hexagonal magnetite nanoprisms: preparation, characterization and cellular uptake.

The capacity of iron oxide nanocrystals to heat tissue when subjected to an alternating magnetic field (AMF hyperthermia) is shape-selective. Although iron oxide nanostructures with numerous shapes have been synthesized to date, hexagonal Fe3O4 prisms of low toxicity remained elusive. Here, we report the use of a dual ligand system permitting feasible reaction conditions to synthesize nearly perfect hexagonal Fe3O4 nanoplatelet structures, with edge length of 45 ± 5 nm and thickness of 5 to 6 nm. Their Specific Absorption Rate (SAR) is >750 W g(Fe)-1. The Fe3O4 hexagons were coated with a dopamine-based ligand to increase dispersibility in aqueous buffers. The Fe3O4 hexagons were only minimally toxic to RAW264.7 cells, which can be utilized in cell-based cancer targeting approaches.

The effect of low-dose inhaled fluticasone propionate on exhaled nitric oxide in asthmatic patients and comparison with oral zafirlukast.

BACKGROUND: Exhaled nitric oxide (ENO) is a noninvasive marker of ongoing inflammation in asthmatic patients. Comparison between inhaled and oral anti-inflammatory medications in reduction of ENO in asthmatic patients has not been performed. OBJECTIVE: We measured changes in ENO, spirometry, need for rescue medication, quality of life (QOL), and diary scores (DS) after inhaled and oral anti-inflammatory therapy in adults with moderate asthma. METHODS: A randomized, double-blind, placebo-controlled, crossover design with 4-week washout periods was used. A plateau level of ENO, measured in parts per billion (ppb), was obtained by chemiluminescence with a Sievers 280NOA as per American Thoracic Society recommendations. Eighteen asthmatic adults (15 Hispanic, with a percentage predicted forced expiratory volume in 1 second (FEV1%) of 50% to 85%) on bronchodilators (beta2) only were studied. Subjects used fluticasone propionate (FP) metered-does inhaler (44 microg), two puffs twice daily, and matching placebo (PB) for 4 weeks. Eight of the asthmatic patients (7 Hispanic, FEV1% 50% to 85%) on bronchodilators only then received blinded zafirlukast (ZK) 20 mg and matching PB twice daily for 4 weeks. RESULTS: Low-dose inhaled FP resulted in significant improvements in ENO, spirometry, QOL, DS, and beta2 use. A significant difference in mean ENO was found (P < 0.01) before and after FP from 34+/-7 ppb to 13+/-3 ppb. A significant improvement was found (P < 0.05) with FEV1% from 75+/-3 to 85+/-3 with FP treatment. The other measured parameters, percentage predicted of peak expiratory flow rate, beta2 need, DS, and QOL measurements, were improved with low-dose FP treatment. No significant reduction was found in ENO with oral ZK for 4 weeks. After oral ZK washout and the second extension arm of placebo, ENO significantly increased back to 47+/-14 ppb (P < 0.05), but spirometry measures did not worsen. Significant improvements were found with DS and beta2 use with oral ZK therapy. CONCLUSIONS: These results reveal ENO is reduced with only low-dose inhaled FP in asthmatic patients not on anti-inflammatory medication. In the smaller extension study, ENO was reduced with FP and not with oral ZK treatment, and ENO levels increased back to near prestudy levels after ZK washout and the second extension arm of placebo. As a marker of inflammation, ENO levels reveal an improvement with anti-inflammatory medication and worsening when it is discontinued.

Imaging cortical dynamics at high spatial and temporal resolution with novel blue voltage-sensitive dyes.

Conventional imaging techniques have provided high-resolution imaging either in the spatial domain or in the temporal domain. Optical imaging utilizing voltage-sensitive dyes has long had the unrealized potential to achieve high resolution in both domains simultaneously, providing subcolumnar spatial detail with millisecond precision. Here, we present a series of developments in voltage-sensitive dyes and instrumentation that make functional imaging of cortical dynamics practical, in both anesthetized and awake behaving preparations, greatly facilitating exploration of the cortex. We illustrate this advance by analyzing the millisecond-by-millisecond emergence of orientation maps in cat visual cortex.