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3.
Br J Anaesth ; 83(2): 328-9, 1999 Aug.
Article in English | MEDLINE | ID: mdl-10618951

ABSTRACT

Urinary oxygen tension may be an index of renal medullary blood flow. The effect of i.v. furosemide on urinary oxygen tension was studied in four patients with indwelling nephrostomy tubes. An intravascular oxygen sensor (Paratrend 7, Biomedical Sensors Ltd, UK) was inserted into the renal pelvis via the nephrostomy and urine oxygen tension measured. In all cases, furosemide 20 mg i.v. produced a decrease in pelvic urinary oxygen. The possible mechanisms and implications are discussed.


Subject(s)
Diuretics/pharmacology , Furosemide/pharmacology , Kidney Medulla/blood supply , Oxygen/urine , Adult , Biomarkers/urine , Humans , Injections, Intravenous , Regional Blood Flow/drug effects
4.
Br J Anaesth ; 69(3): 320-1, 1992 Sep.
Article in English | MEDLINE | ID: mdl-1389852

ABSTRACT

Ten junior doctors with no postgraduate anaesthetic experience attempted to ventilate the lungs of 50 anaesthetized patients, using either a laryngeal mask or a Guedel airway and face mask. Success was defined as the production of two successive tidal volumes exceeding 800 ml within 40 s. The failure rate was significantly greater using the laryngeal mask compared with the face mask (P < 0.05) and the average time was significantly longer with the laryngeal mask than with the face mask (P < 0.01). The results from this investigation suggest the laryngeal mask airway cannot be recommended as a resuscitation device for use by inexperienced operators.


Subject(s)
Cardiopulmonary Resuscitation/instrumentation , Laryngeal Masks , Cardiopulmonary Resuscitation/education , Education, Medical, Graduate , Humans
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