Low-cost biosensors based on a plasmonic random laser on fiber facet.

Low-cost and miniaturized biosensors are key factors leading to the possibility of portable and integrated biomedical system, which play an important role in clinical medicine and life sciences. Random lasers with simple structures provide opportunities for detecting biomolecules. Here, low-cost biosensors on fiber facet for label-free detecting biomolecules are demonstrated based on a plasmonic random laser. The random laser is achieved resorting to a self-assembled plasmonic scattering structure of Ag nanoparticles and polymer film on fiber facet. Refractive index sensitivity and near-surface sensitivity of the biosensor are systematically studied. Furthermore, the biosensor is used to detect IgG through specific binding to protein A, exhibiting the detecting limit of 0.68 nM. It is believed that this work may promote the applications of a plasmonic random laser bio-probe in portable or integrated medical diagnostic platforms, and provide fundamental understanding for the life science.

Tunable polymer lasing in chirped cavities.

Continuously tunable polymer lasing was achieved in one-dimensional, two-dimensional, and compound chirped cavities. The chirped cavity was simply fabricated by using interference lithography and spin coating. Two-dimensional and compound chirped cavities were obtained by employing oblique exposure and double exposure, respectively. The tunability range of two-dimensional chirped cavities was much wider than that of one-dimensional chirped cavities, which varied from 557 nm to 582 nm. The interaction between lasing modes was studied in the compound cavity by introducing an additional nanostructure into the two-dimensional chirped cavities. The threshold of the compound chirped cavities changed with the coupling strength between lasing modes. These results may be helpful for designing compact polymer laser sources.