ABSTRACT
This report summarises the result of the GIFT program at Ramathibodi Hospital during 1990-1991. There were 35 treatment cycles in 34 infertile couples. The age of the females varied from 29 to 41 years. Duration of infertility was 3 to 10 years. GIFT was performed during diagnostic laparoscopy in 26 cycles (78%). Other indications were endometriosis (5 cycles), concurrent with myomectomy (3 cycles) and unexplained infertility (1 cycle). Two cases received CC+HMG for superovulation, the others had GnRHa+HMG. Transvaginal ultrasound guided oocyte pick up yielded 2 to 10 oocytes (mean 5.8 oocytes per cycle). Two to 8 oocytes were transferred. All patients received progesterone or HCG for luteal support. In cases of diagnostic laparoscopy, the findings were normal (10 cases), endometriosis (7 cases), pelvic adhesion (6 cases) and myoma uteri 3 cases). No pregnancy was achieved among 18 GIFT cycles performed in 1990. In 1991, after changing some instruments and methods, there were 5 pregnancies out of 17 GIFT cycles (29%). The factors that influenced the outcome were good selection of instruments and method, maturity of oocytes and semen parameters.
Subject(s)
Gamete Intrafallopian Transfer , Adult , Female , Gamete Intrafallopian Transfer/methods , Humans , Infertility, Female/etiology , Infertility, Female/therapy , PregnancyABSTRACT
In a prospective randomized study, pregnancies with unfavorable cervix and well established gestational age of at least 42 weeks were selected for management by either antepartum fetal testing or prostaglandin gel induction of labor. Of the 108 pregnancies studied, 57 (53%) had labor induced and 51 (47%) continued without intervention. Comparison of the two groups showed no difference in meconium staining, fetal distress, length of first stage of labor, the need for intervention, or the mode of delivery. In terms of Apgar score the neonatal outcome was not significantly different but a greater proportion of the babies (7.8% versus 1.8%) in the noninduced group required intubation. Our data show that there is no particular advantage in letting the pregnancy go beyond 42 completed weeks of gestation especially if prostaglandin is available for induction of labor.
Subject(s)
Fetal Monitoring , Labor, Induced/methods , Pregnancy, Prolonged , Female , Humans , Pregnancy , Pregnancy Outcome , Prospective Studies , Prostaglandins/physiologyABSTRACT
The aim of this study is to determine the clinical presentation, hormonal profiles and ultrasonic ovarian morphology in a group of Thai women with polycystic ovarian disease. The patients consisted of 54 women who had abnormal menstruation, androgenic symptoms, LH to FSH ratio of at least 3 and normal serum prolactin. The clinical and hormonal profiles of the patients were similar to the previous reports from developed countries. The typical ultrasonic cystic appearance of the ovaries was observed in about two-thirds of the patients. The patients with cystic ovaries had lower mean body weight but higher mean serum LH and FSH than the control group.
