[C-reactive protein in women with pre-eclampsia].

UNLABELLED: Preeclampsia is a disorder associated with generalized dysfunction of endothelial cells probably as a result of systematic inflammatory maternal reaction. CRP is a positive marker of inflammation higher at overt preeclampsia than in normal pregnancy. The aim of the present study is to observe the variations of the acute phase protein CRP at women with preeclampsia and those with normal pregnancy in the third trimester. MATERIAL AND METHODS: Sixty women are included in the study, separated into two groups; group A (n = 30), consisted of women with overt preeclampsia and group B (n = 30)- women with normal pregnancy. Plasma levels of CRP are measured by using immunoturbidimetric method and the results are statistically calculated by variative analysis. RESULTS: We found statistically significant difference in plasma concentration of CRP between pregnant women with preeclampsia and those with normal pregnancy (t = 2.92, P < 0.01). CONCLUSION: In conclusion our data about the significantly higher values of CRP at women with preeclampsia are in agreement with the statement for presence of pronounced inflammation at preeclampsia compared with normal pregnancy.

[The significance of kinesitherapy for prophylaxis of osteoporosis].

Osteoporosis is a significant public health problem. It is associated with bone fragility resulting mostly from low bone mass and a concomitant increase in the risk for fracture. Physical exercises are commonly prescribed intervention for prophylaxis of osteoporosis. The purpose of the present study is to state the necessity of appliance kynesitherapy under different forms and methods at osteoporosis.

[Pregnancy in teenagers].

UNLABELLED: Teenage pregnancy is a recognized problem of social and health significance worldwide. World Health Organization considers them as high-risk pregnancies. Teenage birth rates vary by different country. OBJECTIVE: To study the frequency and the obstetric outcome of pregnancy at teenagers in University Hospital "St. George" Plovdiv. SUBJECTS AND METHODS: Nuliparous women who at the period of the delivery were at 11-19 years old and were seen at the obstetric unit of the above hospital were recruited into the study. Observed complications during the pregnancy and delivery were also calculated. RESULTS: For the period of 10 years the teenage pregnancy rate was 8.22%/n= 958/ of all 11657 deliveries /91.78%/. 901 of the teenagers were aged 16 to 19 years /7.73%/ while only 57/0.49%/ were aged 11 to 15 years. In 69.42% /n= 665/ of the cases the deliveries were not complicated; in 30.58% of the cases there were complications or the delivery ended surgicaly. CONCLUSIONS: Pregnancy during teenage years remains major public health problem with lasting repercussions for the teenage mothers and their infants but also for their families and society as a whole. The prevention of the adolescent pregnancy by executing proven and effective programs would decrease its frequency and the complications associated with it.

[Pregnancy outcomes in women of advanced maternal age].

UNLABELLED: During the last decade there is a trend all over the world women at advanced age/older than 35 years old/ and especially educated ones to postpone their reproductive plans. Pregnancy and birth outcomes in women >35 years old I traditionally associated with increasing risk of complications both for the mother and the foetus. OBJECTIVE: To study the frequency and the obstetric outcome of pregnancy at advanced age women in the University Hospital "St. George" Plovdiv. SUBJECTS AND METHODS: Women who at the period of the delivery were at more than 35 years old and were seen at the obstetric unit of the above hospital were recruited into the study. Observed complications during the pregnancy and delivery were also calculated. RESULTS: For the period of 10 years the teenage pregnancy rate was 5.10% /n= 594/5.10% of all 11657 deliveries /94.90%/. 504 of the patients were aged 35 to 39 years /4. 32%/ while only 90 /0.78%/ were aged > 40 years old. In 54.88% of the cases the deliveries were not complicated; in the rest of the cases there were complications or the delivery ended surgicaly. CONCLUSIONS: The increasing frequency of the advanced age pregnancy and deliveries and improved pre and intranatal counseling has made advanced maternal age compatible with successful pregnancy for the great majority of such women.

[Obesity and pregnancy].

UNLABELLED: The increasing frequency of preobesity and obesity in all age groups worldwide can be characterized as a pandemia. Obesity is a public health problem because it is a major contributing factor in the development of hypertension, heart disease, type II diabetes, osteoarthritis, respiratory problems and certain cancer. THE OBJECTIVE OF THE STUDY: To describe the prevalence of preobesity and obesity among pregnant women and to evaluate the impact of preobesity and obesity upon pregnancy and delivery. SUBJECTS AND METHODS: 255 women, aged between 17 and 39 years old are conducted in the study. They have been admited to the Clinic of Obstetrics and Gynecology at the University Hospital "St. George" Plovdiv for the period of for months /January- April 2005/. The data of the patients are obtained from their history of the disease and the dokument of the newborn. BMI was calculated before and at the end of pregnancy. RESULTS: Preobesity and obesity are more frequent at more educated women, nuliparous women and women aged 30 years and more. Obese women had a higher frequency of preeclampsia, gestational diabetes, macrosomia, and operative delivery. 33.33% (n=85) of the pregnant women start their pregnancy with abnormal weight or obesity. At the end of the pregnancy 72.94% (n=186) of them are in condition of preobesity and obesity. CONCLUSION: As overweight and obesity are associate with adverse pregnancy outcomes, the attention of the obstetritian must be directed to so called preconceptual consulting in order to limit the gaining of wight upon the optimal limit before and during pregnancy.

[A case of pulmonary blastoma--a case report and review of the literature].

Pulmonary blastoma is a rare malignant tumor of the lungs, with a frequency of 0.25-0.5% of all primary malignant lung tumors. We present a case of 42-year old man with biphasic pulmonary blastoma The authors discussed the clinical features, laboratory findings, radiologic and CT features, the operative treatment and the pathologic diagnosis.