ABSTRACT
Objetivo: Valorar la respuesta de pacientes diagnosticadas de síndrome vesical doloroso al tratamiento con instilaciones de condroitín sulfato sódico. Material y métodos: Presentamos una serie de casos de pacientes con síndrome vesical doloroso, que siguieron un protocolo de instilación vesical con condroitín sulfato sódico, según el esquema de nuestro centro. Se evaluó la respuesta al tratamiento en lo que respecta a dolor, según la escala de Downie; frecuencia urinaria, según diario miccional y mejoría subjetiva, según la escala de Impresión Mejoría Global de paciente (PGI- I ). Resultados: Veintiocho pacientes con una mediana de edad de 59 años (rango: 22-90) siguieron este protocolo. Entre los antecedentes clínicos el 19,4% había padecido alguna infección del tracto urinario, el 3,8% tuberculosis urinaria, el 7,6% recibió radioterapia pélvica y el 26,9% había tomado anticolinérgicos por vejiga hiperactiva. Evaluamos la respuesta al tratamiento a los 0-3-6 y 12 meses, encontrando que al final del tratamiento el 72,3% había mejorado del dolor vesical y el 75% de los pacientes se encontraba mucho mejor. Conclusiones: El tratamiento con condroitín sulfato sódico en instilación endovescial en el síndrome de vejiga dolorosa produce mejora del dolor, de la frecuencia miccional y de la calidad de vida a largo plazo (AU)
Objective: To assess the response of patients diagnosed with painful bladder syndrome to treatment with instillations of sodium chondroitin sulfate. Material and methods: We present a series of cases of patients with painful bladder syndrome who followed a bladder instillation protocol with sodium chondroitin sulfate, according to our centre's regimen. The response to treatment was assessed with respect to pain, according to the Downie scale; urinary frequency, according to the voiding diary; and subjective improvement, according to the Patient Global Impression of Improvement (PGI- I ) scale. Results: A total of 28 patients with a median age of 59 years (range 22-90) followed this protocol. From the medical histories, 19.4% had suffered an infection of the urinary tract, 3.8% had suffered urinary tuberculosis, 7.6% received pelvic radiation therapy and 26.9% had taken anticholinergic drugs for overactive bladder syndrome. We evaluated the response to treatment at 0, 3, 6 and 12 months and found that at the end of treatment 72.3% of the patients had improved bladder pain and 75% were significantly better. Conclusions: Treatment with sodium chondroitin sulfate through endovesical instillation in painful bladder syndrome improves pain, voiding frequency and quality of life in the long term (AU)
Subject(s)
Humans , Male , Female , Young Adult , Adult , Middle Aged , Aged , Aged, 80 and over , Urinary Bladder Diseases/drug therapy , Pelvic Pain/drug therapy , Chondroitin Sulfates/therapeutic use , Pain Management/methods , Treatment OutcomeABSTRACT
OBJECTIVE: To assess the response of patients diagnosed with painful bladder syndrome to treatment with instillations of sodium chondroitin sulfate. MATERIAL AND METHODS: We present a series of cases of patients with painful bladder syndrome who followed a bladder instillation protocol with sodium chondroitin sulfate, according to our centre's regimen. The response to treatment was assessed with respect to pain, according to the Downie scale; urinary frequency, according to the voiding diary; and subjective improvement, according to the Patient Global Impression of Improvement (PGI-I) scale. RESULTS: A total of 28 patients with a median age of 59 years (range 22-90) followed this protocol. From the medical histories, 19.4% had suffered an infection of the urinary tract, 3.8% had suffered urinary tuberculosis, 7.6% received pelvic radiation therapy and 26.9% had taken anticholinergic drugs for overactive bladder syndrome. We evaluated the response to treatment at 0, 3, 6 and 12 months and found that at the end of treatment 72.3% of the patients had improved bladder pain and 75% were significantly better. CONCLUSIONS: Treatment with sodium chondroitin sulfate through endovesical instillation in painful bladder syndrome improves pain, voiding frequency and quality of life in the long term.
Subject(s)
Chondroitin Sulfates/therapeutic use , Cystitis, Interstitial/drug therapy , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young AdultABSTRACT
The overinfected urachus cyst presents itself in quite different forms. In spite of the accuracy of ultrasound and abdominal CT scan, sometimes the diagnosis of this urachal abnormality is imprecise and even misleading. This article describes the transvesical endoscopic drainage of an infected urachal cyst with optimum result upon the treatment of this condition.
