Conforming collections: assessing medical and allied health collections using Doody's Core Titles.

This study assessed the print collection of an Asian academic medical library using list-checking. The library's book collection was matched to Doody's Core Titles (DCT) subspecialties to identify strong and weak subject areas and understand temporal trends from 2014 to 2020. Basic sciences and nursing were the strongest subspecialties from 2018 to 2020, with many subjects having 100% matches, likely because most academic programs share the same basic sciences foundation subjects and nursing collections had been developed for many years as a long-standing program of the institution. Associated health-related disciplines was the weakest subspecialty. These subjects need to be prioritized in collection development. All subspecialties exhibited an increasing trend of matching between 2014 and 2020. Electronic books were included in the matching to DCT 2020; however, the match was low compared to print only or both print and electronic titles. DCT title matching can not only identify gaps in library collections that need to be filled but also point toward opportunities to develop strong and varied collections in medicine and allied health.

Weak Acid-Base Interactions of Histidine and Cysteine Affect the Charge States, Tertiary Structure, and Zn(II)-Binding of Heptapeptides.

Zinc fingers are proteins that are characterized by the coordination of zinc ions by an amino acid sequence that commonly contains two histidines and two cysteines (2His-2Cys motif). Investigations of oligopeptides that contain the 2His-2Cys motif, e.g., acetyl-His1-Cys2-Gly3-Pro4-Tyr5-His6-Cys7, have discovered they exhibit pH-dependent Zn(II) chelation and have redox activities with Cu(I/II), forming a variety of metal complexes. To further understand how these 2His-2Cys oligopeptides bind these metal ions, we have undertaken a series of ion mobility-mass spectrometry and B3LYP/LanL2DZ computational studies of structurally related heptapeptides. Starting with the sequence above, we have modified the potential His, Cys, or C-terminus binding sites and report how these changes in primary structure affect the oligopeptides positive and negative charge states, conformational structure, collision-induced breakdown energies, and how effectively Zn(II) binds to these sequences. The results show evidence that the weak acid-base properties of Cys-His are intrinsically linked and can result in an intramolecular salt-bridged network that affects the oligopeptide properties.

Collection-based analysis of selected medical libraries in the Philippines using Doody's Core Titles.

OBJECTIVES: This study assessed the book collection of five selected medical libraries in the Philippines, based on Doodys' Essential Purchase List for basic sciences and clinical medicine, to compare the match and non-match titles among libraries, to determine the strong and weak disciplines of each library, and to explore the factors that contributed to the percentage of match and non-match titles. METHOD: List checking was employed as the method of research. RESULTS: Among the medical libraries, De La Salle Health Sciences Institute and University of Santo Tomas had the highest percentage of match titles, whereas Ateneo School of Medicine and Public Health had the lowest percentage of match titles. University of the Philippines Manila had the highest percentage of near-match titles. CONCLUSION: De La Salle Health Sciences Institute and University of Santo Tomas had sound medical collections based on Doody's Core Titles. Collectively, the medical libraries shared common collection development priorities, as evidenced by similarities in strong areas. Library budget and the role of the library director in book selection were among the factors that could contribute to a high percentage of match titles.

[Family life strategies and their relation with malnutrition in children under 2 years old]. / Estrategias familiares de vida y su relación con desnutrición en niños menores de dos años.

OBJECTIVE: To identify the role of family life strategies on malnutrition in children aged 6-23 months of age. MATERIAL AND METHODS: This case-control study was conducted in 1998 in the municipality of Teolocholco, State of Tlaxcala, Mexico, among families with children aged 6-23 months of age. The sample was conformed by 105 cases and 210 controls. Family life strategies were grouped into five types: family composition, means and distribution of family income, family and social networks, and life preservation strategies. Malnutrition was classified according to height for age. Data were analyzed using logistic regression to obtain odds ratios and 95% confidence intervals. RESULTS: Data were collected from 605 families, for a total of 445 controls and 160 cases. The predictive model included mother's schooling, overcrowding, time elapsed between childbirths, per capita monthly income, and time devoted to child-rearing activities. CONCLUSIONS: Family life strategies determine children's nutritional status; understanding the influence of the family on the children's health status is necessary to develop effective programs aimed at improving the nutritional status of children.

Estrategias familiares de vida y su relación con desnutrición en niños menores de dos años / Family life strategies and their relation with malnutrition in children under 2 years old

OBJECTIVE: To identify the role of family life strategies on malnutrition in children aged 6-23 months of age. MATERIAL AND METHODS: This case-control study was conducted in 1998 in the municipality of Teolocholco, State of Tlaxcala, Mexico, among families with children aged 6-23 months of age. The sample was conformed by 105 cases and 210 controls. Family life strategies were grouped into five types: family composition, means and distribution of family income, family and social networks, and life preservation strategies. Malnutrition was classified according to height for age. Data were analyzed using logistic regression to obtain odds ratios and 95 confidence intervals. RESULTS: Data were collected from 605 families, for a total of 445 controls and 160 cases. The predictive model included mother's schooling, overcrowding, time elapsed between childbirths, per capita monthly income, and time devoted to child-rearing activities. CONCLUSIONS: Family life strategies determine children's nutritional status; understanding the influence of the family on the children's health status is necessary to develop effective programs aimed at improving the nutritional status of children.

La consulta subsecuente. Condiciones de sobredemanda en una unidad de medicina familiara / Subsequent consultation as a cause of overuse in a family medicine clinic

En una unidad de medicina familiara con sobredemanda se llevó a cabo un estudio transversal comparativo para conocer la frecuencia y factores relacionados con la consulta subsecuente, factor que ha sido relacionado con la sobredemanda del servicio. Se analizaron 290 expedientes obtenidos al azar de consulta subsecuente otorgada durante el año anterior. Se evaluó la justificación de la subsecuencia basados en la información contenida en el expediente clínico. Sólo 26 por ciento de la consulta subsecuente injustificada fueron las enfermedades cronicodegenerativas (CD) 23.88 por ciento, las infecciones agudas (IA) 21.62 por ciento, el control del niño sano (CNS) 14.86 por ciento, el control prenatal (CP) 13.15 por ciento y los padecimientos traumáticos (PT) 9.21 por ciento para la justificada fueron CD 46.15 por ciento, CNS 15.89 por ciento, CP 10.75 por ciento, IA 8.78 por ciento y PT 6.07 por ciento. Hubo diferencia estadísticamente significativa con mayor número de CD para la consulta subsecuente justificada (p < 0.05) y de IA para la injustificada (p < 0.05). Las consultas subsecuentes injustificadas se debieron a no resolución del padecimiento por deficiencias diagnóstico-terapéuticas, omisión en el envío con la enfermera materno-infantil (EMI) y motivos del paciente. Las características de los pacientes no fueron diferentes, sin embargo, la edad mayor a 50 años, tipo de derechohabiencia (jubilado, pensionado y sus beneficiarios) y escolaridad media y media superior fueron características relacionadas con mayor subsecuente la generaron principalmente las enfermedades CD, el CNS y el CP que no fueron derivados oportunamente a EMI. Se propone atención grupal del paciente con Cd y supervisar al médico familiar para que aquellos que requieran CNS y CP sean enviados oportunamente a EMI

Comportamiento de los valores de IgET del suero y de los eosinofilos en sangre periferica en pacientes asmáticos atópicos / Behavior of IgET valves of peripheric blood serum in atopical asthmatic patients

En 56 pacientes asmáticos atópicos fue determinada la concentración de IgET del suero y en 46 de ellos la de eosinófilos en sangre periférica. Se encontró IgET elevada en 49 pacientes (87,6 por ciento) y eosinofilia en 18 de los 46 individuos en que se practicó la determinación (39,3 por ciento).Se observó, por otra parte, eosinofilia en el 41,5 por ciento de los pacientes con IgET elevada y sólo en 14,3 por ciento de ellos con IgET normal. En cambio, en todos los pacientes con eosinofilia, la concentración de IgET se encontró elevada. Los resultados ratifican que el valor de IgET del suero cuando elevado, y descartadas otras posibles causas del fenómeno, es un buen instrumento para el diagnóstico de atopía. Pero un valor normal de ese parámetro no lo descarta

Patron de respuesta al broncodilatador en el paciente / Pattern respose to the bronchodilator in ashmatic patient

Fue estudiada la respuesta al broncodilatador en 54 pacientes (49 asmáticos "puros" y 5 con asma más enfisema y/o bronquitis crónica asociados) con el fin de determinar los diferentes patrones de respuesta al broncodilatador. No encontramos en ninguno de estos grupos de sujetos, respuesta aislada a volumen (Patrón B). La respuesta doble aumentó con la edad de los pacientes. De los valores dinámicos el FEF 25-75 fue con más frecuencia varió en el grupo total de pacientes. Estimamos importante para categorizar al paciente obstrutivo como "reversible" considerar la respuesta al broncodilatador de todos los parámetros dinámicos de la curva CVF y no sólo la respuesta en la CVF y en la relación VEF/CVF 1

Teofilinemia en "estado de equilibrio" con dosis múltiples de una teofilina de liberación sostenida / Theophiline in \"steady state\" with dosage of a sustained release theophiline

Para verificar las dosis de una Teofilina de liberación sostenida (Teobid), con las cuales se obtienen concentraciones plasmáticas óptimas en estado de equilibrio (10 a 20 microgramos/ml) y determinar el porcentaje de variación entre los niveles valle y pico de estas concentraciones se seleccionaron por conveniencia 16 pacientes asmáticos de mediana severidad, de ambos sexos, mayores de 9 años y menores de 60, entre los consultantes a la Unidad de Asma del Servicio de Neumonología del Hospital General "Dr. Luis Gómez López" de Barquisimeto. Inicialmente todos los pacientes recibieron 5mg/km de Teobid cada 12 horas durante 4 días, al término de los mismos, las dosis fueron mantenidas o corregidas de acuerdo a las cifras de teofilinemia (grupo A) o de acuerdo a la respuesta clínica (grupo B). Los resultados indican que las dosis con las cuales se consiguen niveles plasmáticos dentro del rango terapéutico fueron de 6,6 mg/km cada 12 horas y que las variaciones de las concentraciones plasmáticas valle y pico en estado de equilibrio estuvieron por debajo del 30% . Lo cual indica la estabilidad plasmática con el régimen de dosificación (cada 12 horas) recomendado para esta presentación de Teofilina