ABSTRACT
Introducción: Las estaciones de servicio de gasolina actualmente tienen dificultad en certificar sus procesos de funcionamiento ante los entes correspondientes; por tal motivo, surgió el interés de cumplir con estándares inter-nacionales mediante la aplicación integral de dos normas técnicas colombianas, como lo son la ISO 9001:2015 y la ISO 45001:2018. Objetivo: Diseñar y aplicar un modelo integrado de gestión de la calidad y seguridad y salud en el trabajo bajo los requisitos de las normas técnicas colombianas ISO 9001 e ISO 45001 para las estaciones de servicio de gasolina de Boyacá, con aplicación en una empresa piloto. Metodología: Se desarrolló en tres fases. Inicialmente, se diagnosticaron las condiciones actuales de las estaciones de servicio de gasolina; posteriormente, se diseñó un modelo de integración bajo las normas objeto de estudio, y, por último, se aplicó dicho modelo a la empresa piloto. Resultados: Se obtuvo el diseño de un sistema de gestión integral basado en calidad, seguridad y salud en el trabajo mediante la aplicación de dos normas técnicas como lo son la ISO 9001:2015 e ISO 45001:2018, respec-tivamente. Conclusiones: Este sistema integrado de gestión es el primer paso para que las estaciones de servicio de gasolina puedan ofrecer calidad en la venta de combustible, alineado con las exigencias normativas expuestas en la Resolu-ción 0312 de 2019, y para cumplir los requisitos técnicos de la Resolución 40405 de 2020
Introduction: Gasoline service stations currently have difficulty certifying their operating processes by corresponding entities, for this reason there is an interest in complying these standards through the comprehensive application of two technical standards such as ISO 9001: 2015 and ISO 45001:2018. Objective: Design and apply an integrated model of quality management and occupational health and safety, under requirements of the Colombian technical standard ISO 9001 and ISO 45001 for ga-soline service stations in Boyacá, with a pilot company.Methodology: It was developed in three phases, initially it was discovered in the current conditions of gasoline service stations, later an integration model was started under the standards and finally the model was applied to the pilot Company. Results: The design of a comprehensive management system based on quality, safety and health at work was obtained through the application of two technical standards such as ISO 9001:2015 and ISO 45001:2018 respectively. Conclusions: An integrated management system based on ISO 9001:2015 and ISO 45001:2018 stan-dards was designed, which is the first step to gasoline service stations can offer quality in the sale of fuel aligned with the regulatory requirements in resolution 0312 of 2019 and to meet the technical requirements of resolution 40405 of 2020
Introdução: Atualmente, os postos de gasolina têm dificuldade para certificar seus processos ope-racionais perante as entidades correspondentes; por esse motivo, surgiu o interesse em cumprir as normas internacionais por meio da aplicação integral de duas normas técnicas colombianas, como a ISSO 9001:2015 e a ISSO 45001:2018. Objetivo: projetar e implementar um modelo integrado de gestão de qualidade e saúde e segurança ocupacional de acordo com os requisitos das normas técnicas colombianas ISO 9001 e ISO 45001 para postos de gasolina em Boyacá, com aplicação em uma empresa piloto. Metodologia: foi desenvolvida em três fases. Inicialmente, foram diagnosticadas as condições atuais dos postos de gasolina; em seguida, foi projetado um modelo de integração de acordo com os padrões em estudo e, por fim, o modelo foi aplicado à empresa piloto. Resultados: o projeto de um sistema de gestão integrado baseado em qualidade, segurança e saúde no trabalho foi obtido por meio da aplicação de duas normas técnicas, como a ISO 9001:2015 e a ISO 45001:2018, respectivamente. Conclusões: Esse sistema de gerenciamento integrado é o primeiro passo para que os postos de combustíveis ofereçam qualidade na venda de combustíveis, alinhados com os requisitos regulatórios estabelecidos na Resolução 0312 de 2019, e atendam aos requisitos técnicos da Resolução 40405 de 2020
Subject(s)
Occupational Health , Occupational Risks , Total Quality Management , Enacted StatutesABSTRACT
The aim of the present study was to compare the acute effect of a static- vs dynamic-based stretching warm-up on standing long jump (SLJ) performance in primary schoolchildren. The sample was composed of 76 schoolchildren, 43 girls and 33 boys, aged 9-10 years old from three fourth-grade classes of Primary Education. The three groups were cluster-randomly assigned to the control (CG), static (SG) or dynamic (DG) groups. All the schoolchildren performed a standardized warm-up consisting of mobility exercises (five minutes), jogging (five minutes) and the SLJ test. Afterwards the CG schoolchildren received jump theory (eight minutes), the SG performed static stretching (eight minutes) and the DG performed dynamic-bounces stretching (eight minutes). Afterwards, all of them performed the SLJ test again. The results of the one-way ANOVA (F 2,73 = 34.184; p < 0.001; η2p = 0.484), followed by the pairwise comparisons with the Bonferroni adjustment, showed that the DG students (M Δ = 11.07, SE = 1.42) made a significant statistical improvement in their SJL levels compared with the CG (M Δ = -3.00, SE = 1.89; p < 0.001, d = 1.51) and SG students (M Δ = -1.85, SE = 0.67; p < 0.001, d = 1.38). However, statistically significant differences between the CG and SG students were not found (p > 0.05, d = 0.12). The dynamic-bouncing stretch as a final part of a warm-up improves explosive strength performance in primary schoolchildren, and seems to be a good option before carrying out explosive strength activities of the lower body.
ABSTRACT
A sugar solution measurement system was developed based on the dielectric properties of the sucrose molecule. An ac conductivity and tan δ study as a function of the frequency was performed to find the suitable frequency range for the measuring system. The results indicate that it is possible to obtain a better response of the sensor using the frequencies as the maxima peak in tan δ appears. Developed setup for sucrose solution was appropriate to measure in a 0.15 to 1 g/mL range with an experimental error of about 3%. The proposed system improves the measurement time over some other methods.
ABSTRACT
The apolipoprotein E ε4 allele (APOE4) and family history of dementia (FH) are well-known risk factors for the development of sporadic Alzheimer's disease. We assessed the effects of these risk factors on gray matter (GM) volume in 295 cognitively healthy middle-aged community-dwelling subjects. Voxel-based morphometry was used to study GM volume differences between high- and low-risk subjects, based on APOE4 carriership (n = 74), first-degree FH (n = 228), or both (n = 62). No significant results were found using a corrected p value. Using a more lenient threshold (p < 0.001 and minimum cluster size of 100 voxels), APOE4 carriers had reduced GM in the striatum compared to noncarriers. Subjects with FH had reduced GM in right precuneus compared to subjects without FH. Maternal and paternal FH provided similar atrophy patterns. APOE4 carriers with FH had GM reductions in bilateral insula compared to subjects with neither APOE4 nor FH. We conclude that a family history of dementia and APOE4 carriership are both associated with regional GM decreases in cognitively healthy middle-aged subjects, with differential effects on brain regions typically affected in Alzheimer's disease.
Subject(s)
Apolipoprotein E4/genetics , Dementia/genetics , Gray Matter/pathology , Heterozygote , Aged , Alzheimer Disease/etiology , Atrophy , Female , Humans , Male , Middle Aged , Risk FactorsABSTRACT
Zinc porphyrin dimers and trimers, in which the porphyrins are connected via a ruthenium metal core, exhibit large third-order nonlinear optical absorption coefficients and refractive indices. These properties are a result of the presence of multiple porphyrins, which lead to an extension of the π-conjugated system and the octupolar effect.
ABSTRACT
Self-assembled stacks of trimeric manganese porphyrins exhibit high activity in the photocatalytic epoxidation of stilbene using O2 as the oxidant. The supramolecular structure of the catalyst leads to increased stability of the system and enhances the stereoselectivity of the reaction.
ABSTRACT
The work presented here is part of a larger study to identify novel technologies and biomarkers for early Alzheimer disease (AD) detection and it focuses on evaluating the suitability of a new approach for early AD diagnosis by non-invasive methods. The purpose is to examine in a pilot study the potential of applying intelligent algorithms to speech features obtained from suspected patients in order to contribute to the improvement of diagnosis of AD and its degree of severity. In this sense, Artificial Neural Networks (ANN) have been used for the automatic classification of the two classes (AD and control subjects). Two human issues have been analyzed for feature selection: Spontaneous Speech and Emotional Response. Not only linear features but also non-linear ones, such as Fractal Dimension, have been explored. The approach is non invasive, low cost and without any side effects. Obtained experimental results were very satisfactory and promising for early diagnosis and classification of AD patients.
Subject(s)
Alzheimer Disease/diagnosis , Diagnostic Techniques and Procedures , Speech/physiology , Adult , Aged , Aged, 80 and over , Alzheimer Disease/physiopathology , Automation , Emotions , Female , Fractals , Humans , Male , Middle Aged , Pilot Projects , Signal Processing, Computer-Assisted , Temperature , Young AdultABSTRACT
Este estudio establece una correlación entre la exposición a perclorato de amonio y la presencia clínica de alteraciones en el eje hipotálamo-hipófisis- tiroides, tomando como referencia diferentes dosis de aplicación desde la aceptada como dosis segura hasta un incremento significativo de dicha dosis. El trabajo reviste gran importancia debido a que esta sustancia química es uno de los compuestos de mayor uso como pesticida en el departamento de Boyacá. Mediante ensayos inmunoenzimáticos con microplacas; con los Kit comerciales Kit Accubind Elisa Microwells TSH y Kit Accubind Elisa Microwells T4L y el análisis clínico se pudo establecer la existencia de alteraciones en el eje hormonal, lo que puede ser indicador en el futuro de un alto riesgo por parte de los individuos que manipulen esta sustancia.
This study establishes a correlation between exposure and clinical alterations in the hypothalamic-pituitary-thyroid axis. Different dosages were applied, from the accepted safe dosage up to a significant increase dosage. The study was carried out under the laboratory animal center conditions at Universidad of Boyacá (Colombia). Due that ammonium perchlorate is one of the most used compounds as pesticide in Boyacá department this type of studies are extremely important. Using enzyme immunoassay in micro-plate (Accubind Elisa Microwells TSH and Kit Accubind Elisa Microwells T4L ) and following clinical analysis alterations in the hormonal axis were found which could be be indicative of a possible high risk in the future for individuals who handle this substance.
Subject(s)
Humans , Thyroid Gland , Pituitary Gland , Immunoglobulins, Thyroid-Stimulating , HypothalamusABSTRACT
Rh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H(2)O)](2+) was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. Apparently, Rh(III)-TsDPEN is prone to severe diffusion limitations, necessitating further developments. Overall, a promising concept for chemoenzymatic redox catalysis is proposed, which may overcome some of the current limitations such as catalyst cost and incompatibility of Rh with some biocatalysts.
Subject(s)
NADP/metabolism , Catalysis , Oxidation-ReductionABSTRACT
Several molecular systems for direct detection of Mycobacterium tuberculosis complex (MTBC) have recently been developed. The GenoQuick MTB assay (GQ-MTB) used in this study detected 82 of the 96 (85.4%) samples with MTBC, including 50 of 64 (78.1%) samples with negative acid-fast bacillus smears. Fifteen samples containing nontuberculous mycobacteria were also studied: 13 were GQ-MTB negative, one was positive, and one was indeterminate. GQ-MTB showed good effectiveness for the direct detection of MTBC from clinical samples.
Subject(s)
Bacteriological Techniques/methods , Molecular Diagnostic Techniques/methods , Mycobacterium tuberculosis/isolation & purification , Tuberculosis/diagnosis , Tuberculosis/microbiology , Humans , Mycobacterium tuberculosis/genetics , Sensitivity and SpecificityABSTRACT
Sixty-four of 85 (75.3%) smear-negative respiratory (n = 78) and nonrespiratory (n = 7) samples with positive cultures of Mycobacterium tuberculosis complex (MTC) were detected by the GeneXpert system using the Xpert MTB/RIF assay (GX). In addition, GX found rpoB mutations in all six of the rifampin-resistant strains detected. The test was negative in 20 culture-negative and 20 nontuberculous culture-positive samples (100% specificity). GX offers high potential for the diagnosis of tuberculosis due to its capacity for direct detection of MTC, its rapidity, and its simplicity.
Subject(s)
Bacterial Proteins/genetics , Bacteriological Techniques/methods , Mycobacterium tuberculosis/drug effects , Mycobacterium tuberculosis/isolation & purification , Polymerase Chain Reaction/methods , Tuberculosis/diagnosis , DNA, Bacterial/genetics , DNA-Directed RNA Polymerases , Drug Resistance, Bacterial , Humans , Mutant Proteins/genetics , Mycobacterium tuberculosis/genetics , Sensitivity and Specificity , Time Factors , Tuberculosis/microbiologyABSTRACT
Reportamos observaciones de individuos albinos en tres especies de aves peruanas, el Zambullidor Grande (Podiceps major), el Pelícano peruano (Pelecanus thagus) y el Churrete cordillerano (Cinclodes fuscus). Los individuos eran albinos parciales casi totalmente blancos, aparentemente adultos, que mostraron un comportamiento normal entre sus conespecíficos. La supervivencia después de varios meses pudo ser comprobada para el Pelícano peruano y el Churrete cordillerano. Debido a que la información publicada sobre albinismo en aves peruanas es muy escasa, se realizó una revisión y se recopilaron registros para otras nueve especies que son también presentados.
We report observations of albino individuals in three species of Peruvian birds, Great Grebe (Podiceps major), Peruvian Pelican (Pelecanus thagus) and Bar-winged Cinclodes (Cinclodes fuscus). These were all three mostly white partial albinos, apparently adult birds that showed normal behavior among normal conspecific individuals. Survival after several months was confirmed for the Peruvian Pelican and the Bar-winged Cinclodes. Since published information on albinism in Peruvian birds is very scarce, a revision was made and records for nine other species were compiled and are also presented.
Subject(s)
Animals , Albinism , Birds/abnormalitiesABSTRACT
AIMS: To evaluate the effect of a whole formula diet on nutritional and cognitive status in Alzheimer's disease patients. METHODS: Patients were randomly assigned to two interventions: a whole formula diet based on lyophilised foods (Treatment Group, n=24) or nutritional advice (Control Group, n=29). Energy intake, body weight, biochemistry, Mini Nutritional Assessment (MNA) and Pfeiffer's tests were determined at baseline and at 3 months of treatment. RESULTS: No differences were observed between groups at baseline. Energy intake tended to increase in the Treatment Group and to decrease in the Control Group, although differences were not significant. The improvement in MNA and Pfeiffer test scores was not significantly different between groups. Body weight increased by 2.06+/-1.9 kg in the Treatment Group and by 0.32+/-3.04 kg in the Control Group (P=0.007). The increases in albumin (P=0.007), haemoglobin (P=0.002) and serum ferritin (P=0.009) were higher in the Treatment Group than in controls. A similar rate of serious adverse events (hospitalisation or death) was observed in both groups. CONCLUSIONS: Administration of this whole formula has a positive impact on nutritional status. The great diversity in textures and tastes enable these formulations to be administered to a wide range of patients with or without liquid dysphagia.
Subject(s)
Alzheimer Disease/diet therapy , Alzheimer Disease/metabolism , Cognition , Food, Formulated , Aged , Alzheimer Disease/psychology , Body Weight , Energy Intake , Female , Humans , Male , Nutritional Status/physiology , Prospective Studies , SpainABSTRACT
Los comprimidos para empleo oral de misoprostol se están usando en nuestro país como en otros para la inducción del trabajo de parto en que la experiencia acumulada ha mostrado ser una alternativa segura y eficiente. Es necesario precisar las exactas indicaciones del medicamento y se presenta la experiencia del Hospital de Castro. Se destaca que los malos resultados perinatales ocurren en el grupo en que fracasa la inducción con misoprostol como en aquellos en que se sospecha una insuficiencia placentaria (síndrome hipertensivo, oligoamnios y retardo del crecimiento intrauterino)
Subject(s)
Humans , Female , Infant, Newborn , Pregnancy , Adolescent , Adult , Labor, Induced , Misoprostol/pharmacology , Administration, Intravaginal , Asphyxia Neonatorum , Birth Weight , Fetal Growth Retardation , Gestational Age , Oxytocin/pharmacology , Parity , Pregnancy ComplicationsABSTRACT
Un sistema de control de la calidad del agua de consumo debe contemplar la integración de los diversos niveles de decisión y de ejecución (muestreo, laboratorio, comunicación, otros). Así también de los organismos de control con los encargados de la provisión del agua. El sistema debe tender a lograr una respuesta rápida y eficaz ante las alteraciones en los sistemas de aprovisionamiento y una flexibilidad tal que le permita adaptarse a la mayor demanda de la población en cuanto a cantidad y calidad del control y a los avances en las técnicas analíticas. La provincia del Chubut ha seguido esta tendencia mediante el Programa de Control de la Calidad del Agua de Consumo llevado a cabo por el Departamento de Saneamiento Básico, dependiente de la Dirección de Medio Ambiente del Sistema Provincial de Salud. Se describe brevemente su historia y organización, esperando que esta experiencia pueda ser de utilidad para otros sistemas
Subject(s)
Drinking Water , Water Quality Control , ArgentinaABSTRACT
Un sistema de control de la calidad del agua de consumo debe contemplar la integración de los diversos niveles de decisión y de ejecución (muestreo, laboratorio, comunicación, otros). Así también de los organismos de control con los encargados de la provisión del agua. El sistema debe tender a lograr una respuesta rápida y eficaz ante las alteraciones en los sistemas de aprovisionamiento y una flexibilidad tal que le permita adaptarse a la mayor demanda de la población en cuanto a cantidad y calidad del control y a los avances en las técnicas analíticas. La provincia del Chubut ha seguido esta tendencia mediante el Programa de Control de la Calidad del Agua de Consumo llevado a cabo por el Departamento de Saneamiento Básico, dependiente de la Dirección de Medio Ambiente del Sistema Provincial de Salud. Se describe brevemente su historia y organización, esperando que esta experiencia pueda ser de utilidad para otros sistemas (AU)
