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1.
Obesity (Silver Spring) ; 32(6): 1169-1178, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38664956

ABSTRACT

OBJECTIVE: The objective of this study was to compare the magnitude of adaptive thermogenesis (AT), at the level of resting energy expenditure (REE), after a very low-energy diet alone or combined with Roux-en-Y gastric bypass or sleeve gastrectomy, as well as to investigate the association between AT and changes in appetite. METHODS: A total of 44 participants with severe obesity underwent 10 weeks of a very low-energy diet alone or combined with Roux-en-Y gastric bypass or sleeve gastrectomy. Body weight and composition, REE, subjective appetite feelings, and plasma concentrations of gastrointestinal hormones were measured at baseline and week 11. AT, at the level of REE, was defined as a significantly lower measured versus predicted (using a regression model with baseline data) REE. RESULTS: Participants lost 18.4 ± 3.9 kg of body weight and experienced AT, at the level of REE (-121 ± 188 kcal/day; p < 0.001), with no differences among groups. The larger the AT, at the level of REE, the greater the reduction in fasting ghrelin concentrations and the smaller the reduction in feelings of hunger and desire to eat in the postprandial state. CONCLUSIONS: Weight-loss modality does not seem to modulate the magnitude of AT, at the level of REE. The greater the AT, at the level of REE, the greater the drive to eat following weight loss.


Subject(s)
Energy Metabolism , Gastrectomy , Gastric Bypass , Ghrelin , Obesity, Morbid , Thermogenesis , Weight Loss , Humans , Female , Male , Thermogenesis/physiology , Adult , Weight Loss/physiology , Obesity, Morbid/surgery , Obesity, Morbid/diet therapy , Obesity, Morbid/blood , Obesity, Morbid/psychology , Energy Metabolism/physiology , Middle Aged , Ghrelin/blood , Gastrectomy/methods , Appetite/physiology , Diet, Reducing , Adaptation, Physiological , Bariatric Surgery , Basal Metabolism/physiology , Caloric Restriction/methods , Postprandial Period/physiology , Body Composition
2.
Nutrients ; 15(24)2023 Dec 16.
Article in English | MEDLINE | ID: mdl-38140384

ABSTRACT

BACKGROUND: Maintaining a healthy lifestyle is crucial for safeguarding the well-being and quality of life perception, appropriate growth, and development of children and adolescents, while also mitigating the risk of future adult-onset diseases. OBJECTIVE: To assess associations between perceived quality of life and healthy lifestyle and related outcomes in Spanish children and adolescents. METHODS: Cross-sectional analysis of 8-16-year-old children and adolescents (n = 3534) were included in the nationwide study of Physical Activity, Sedentarism, and Obesity in Spanish Youth (PASOS). Data were collected through (1) questionnaires on health-related quality of life (HRQoL), healthy lifestyle outcomes (dietary intake, physical fitness, sleep, and screen time), and (2) anthropometric measurements for weight status assessment. Data were analysed by logistic regression, using the health-related quality of life (HRQoL) as the grouping variable. RESULTS: Participants with a lower HRQoL were those with a lower adherence to the MedDiet and lower achievement of the recommended daily intake of fruit and vegetables. They were also less likely to follow the recommendations for screen time and sleep (with the exception of the weekend) compared to participants with a higher HRQoL. Participants with a lower HRQoL showed a lower healthy weight status and poorer physical fitness than those with a higher HRQoL. CONCLUSIONS: Healthy eating habits, healthy weight status (normal weight), appropriate sleep time, physical fitness, and limited screen time play a crucial role in the perceived quality of life in children and adolescents.


Subject(s)
Obesity , Quality of Life , Child , Humans , Adolescent , Cross-Sectional Studies , Exercise , Life Style , Healthy Lifestyle
3.
Dig Liver Dis ; 2023 Nov 25.
Article in English | MEDLINE | ID: mdl-38008698

ABSTRACT

BACKGROUND: Physical exercise (PE) has been proven to be beneficial in patients with cirrhosis; effects in cognitive function and cerebral hemodynamics, are yet to be explored. AIM: To evaluate the effects of a PE program (LFN-exercise protocol) in hepatic/cerebral hemodynamics. METHODS: Randomized open clinical trial in patients with cirrhosis; Control: Diet(n = 13),Intervention: Diet + exercise(n = 14) for 12 weeks. Patients received an educational session, mental exercises (printed book and sudoku), and high-protein diet. Exercise intervention consisted of walking 4 times/week with an intensity rated between 12 and 14 on the Borg scale, monitored through bracelet accelerometers. Patients received weekly text messages to encourage adherence and had monthly in-person visits. RESULTS: Patients were mainly Child-Pugh A(88.9 %), median MELD 8(8-10), mean age 53±8 years. In the exercise group the number of steps increased from 9667±3008 to 11,931±4463 (p = 0.002), vs 8004±3224 to 8903±3504 (p = 0.053) in controls. Exercise decreased HVPG from 11(8-14) to 8(6-11)mmHg (p = 0.032) vs no change in the control group from 14(12-16) to 15(11-17)mmHg (p = 0.959). Intervention group showed better cerebral hemodynamics, cognitive function, nutritional status and quality of life after the intervention. Adherence was >90 %, with no adverse events. CONCLUSION: The LFN-exercise protocol improves portal hypertension, cerebral hemodynamics and cognitive function, as well as nutritional status and quality of life. GOV NUMBER: NCT03932552.

4.
Front Public Health ; 11: 1137512, 2023.
Article in English | MEDLINE | ID: mdl-37113187

ABSTRACT

Background: COVID-19 has harmed restaurants, but customer preferences remain unknown. This study aims to determine the needs, barriers, interests, and food choice changes in restaurants and customers before and during the COVID-19 pandemic in Tarragona Province (Spain). Methods: An observational cross-sectional study conducted in spring 2021 collected Mediterranean offerings, food safety, and hygiene information about the pandemic through online surveys and focus group interviews with restaurateurs and customers about the changes in their needs and new barriers. Results: Fifty-one restaurateurs (44 survey, 7 focus group) and 138 customers (132 survey, 6 focus group) were included. In relation to the economic, emotional, and uncertainty restaurateurs' barriers detected, they implemented measures to tackle it: buy less and more often, reduce restaurant staff and reduce the restaurants offer, among others. Some customers reported changes in their restaurant orders, specifically increasing their takeaway orders. The Mediterranean diet offer (AMed criteria) remained without noticeable changes in any of the criteria. After lockdown, compared to before lockdown, restaurateurs increased their takeaway offerings by 34.1% (p < 0.001) and their use of digital menus by 27.3% (p < 0.001) because of customer demand. The use of local products in the menus remained high. The cleaning and disinfection tasks increased by 21.1% (p = 0.022), and the use of hydroalcoholic solutions increased by 13.7% (p = 0.031). Conclusion: In restaurants, the first COVID-19 lockdown increased takeaway orders, sanitation, and digital communication. This study provides valuable information for adapting gastronomic offerings during challenging situations.


Subject(s)
COVID-19 , Restaurants , Humans , Cross-Sectional Studies , Spain/epidemiology , Pandemics , COVID-19/epidemiology , COVID-19/prevention & control , Communicable Disease Control
5.
Antibiotics (Basel) ; 12(4)2023 Apr 05.
Article in English | MEDLINE | ID: mdl-37107072

ABSTRACT

Bixa orellana is a native and cultivated species of Ecuador commonly known as achiote (annatto), this species is very versatile with a wide variety of uses and applications of its leaves, fruits and seeds. In this study, the chemical composition, enantiomeric distribution and biological activity of essential oil isolated from the leaves of Bixa orellana were determined. Hydrodistillation was used to isolate the essential oil. Gas chromatography coupled with mass spectrometry was used to determine the qualitative composition, a gas chromatograph equipped with a flame ionization detector was used to determine quantitative composition and gas chromatography on an enantioselective column was used to determine enantiomeric distribution. Antibacterial activity was determined using the broth microdilution method, for which we used three Gram-positive cocci bacteria, a Gram-positive bacilli bacterium and three Gram-negative bacilli bacteria. 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic (ABTS) acid radical cation and 2,2-diphenyl-1-picrylhydryl (DPPH) free radical were used as reagents for determining the antioxidant activity of the essential oil. The spectrophotometric method was used to analyze acetylcholinesterase inhibitory effect of the essential oil. The yield of leaves in essential oil was 0.13 ± 0.01% (v/w). A total of 56 chemical compounds, which represent 99.25% of the total composition, were identified in the essential oil. Sesquiterpene hydrocarbons were the most representative group in number of compounds and relative abundance with 31 compounds and 69.06%, respectively. The principal constituents were found to germacrene D (17.87 ± 1.20%), bicyclogermacrene (14.27 ± 0.97%), caryophyllene < (E)- > (8.56 ± 1.24%) and pinene <α-> (6.34 ± 0.13%). Six pairs of enantiomers were identified in the essential oil of Bixa orellana. The essential oil presented strong activity against the Enterococcus faecium (ATCC 27270) with an MIC of 250 µg/mL and weak activity against Enterococcus faecalis (ATCC 19433) and Staphylococcus aureus (ATCC 25923) with an MIC of 1000 µg/mL. The antioxidant activity of the essential oil was strong according to ABTS methods with a SC50 of 61.49 ± 0.04 µg/mL and was moderate in DPPH with a SC50 of 224.24 ± 6,4 µg/mL. Additionally, the essential oil reported moderate anticholinesterase activity with an IC50 of 39.45 ± 1.06 µg/mL.

6.
Nutrients ; 15(4)2023 Feb 08.
Article in English | MEDLINE | ID: mdl-36839228

ABSTRACT

Childhood obesity is a major international problem, and unhealthy eating habits remain widespread. Increasing the frequency of meals of nutritious food can help children to regulate their appetite and maintain a healthy weight. However, there is scarce prospective evidence on the relationship between the meal frequency and weight outcomes. Therefore, the objective of the present study was to determine the prospective association between the meal frequency, body mass index, and waist circumference in Spanish children. Additionally, we analyzed the impact of the meal frequency on the incidence of excessive weight and abdominal obesity. The study included 1400 children with a mean (SD) age of 10.1 (0.6) and an average follow-up of 15 months. Anthropometric measurements, including the body weight, height, and waist circumference, were measured by trained personnel, and children were asked about whether they usually had the following meals: breakfast, a mid-morning snack, lunch, an afternoon snack, and dinner. Multiple linear regression models revealed a significant (p < 0.05) inverse association between the meal frequency with a standardized BMI (zBMI) and the waist-to-height ratio (WHtR) after adjusting for sex, age, allocation to an intervention group, school, maternal education, physical activity, diet quality, and for the corresponding outcome variable at the baseline. Furthermore, the odds of developing abdominal obesity or excessive weight during the follow-up significantly decreased with an increase in the meal frequency after controlling for the same confounders. In conclusion, a higher meal frequency at the baseline was predictive for a lower zBMI, WHtR, and odds of the incidence of excessive weight and abdominal obesity.


Subject(s)
Pediatric Obesity , Humans , Child , Infant , Pediatric Obesity/epidemiology , Obesity, Abdominal/epidemiology , Prospective Studies , Meals , Body Mass Index , Feeding Behavior , Weight Gain
7.
Can J Physiol Pharmacol ; 101(2): 90-105, 2023 Feb 01.
Article in English | MEDLINE | ID: mdl-36688470

ABSTRACT

Phenolic acids are recognized as chemopreventive and chemotherapeutic agents. Altered glucose and glutamine metabolism are recognized hallmarks of cancer cells. We aimed to test the influence of phenolic acids on glucose and glutamine cellular uptake by a breast (MCF-7) and a pancreatic (AsPC-1) cancer cell line. Several phenolic acids (caffeic, ferrulic, proctocatechuic, coumaric and gallic acid) affected 3H-glutamine and/or 3H-deoxy-d-glucose (3H-DG) uptake. Gallic acid (100 µM) caused a 3-fold increase in 3H-DG uptake by AsPC-1 cells, associated with a 3.7-fold increase in lactic acid production. Gallic acid stimulated GLUT1-mediated 3H-DG uptake and increased the affinity of this transporter for 3H-DG. We further verified that gallic acid does not change GLUT1 transcription rates and cellular redox state and that its effect does not involve PI3K, mTOR and MAP kinases and is not associated with a proproliferative effect. Gallic acid also increased 3H-DG uptake by MCF-7 cells, although less potently. Further investigation is necessary to elucidate the cellular pathways involved in this effect of gallic acid.


Subject(s)
Gallic Acid , Pancreatic Neoplasms , Humans , Gallic Acid/pharmacology , Glucose Transporter Type 1 , Glutamine , Glucose/metabolism , MCF-7 Cells , Pancreatic Neoplasms/drug therapy
8.
Repert. med. cir ; 32(3): 235-240, 2023. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1526328

ABSTRACT

Introducción: se consideran prescripciones inapropiadas de medicamentos cuando el riesgo supera el beneficio, o en las que hay un incremento en el potencial de interacciones farmacológicas. Para evitarlo en el adulto mayor se han desarrollado herramientas como los criterios Beers y los PRISCUS. Objetivo: identificar las prescripciones potencialmente inapropiadas en la población adulta mayor que consultó al servicio de medicina interna del Hospital Universitario Hernando Moncaleano Perdomo mediante los listados Beers y PRISCUS. Materiales y métodos: estudio observacional descriptivo de corte transversal en pacientes mayores de 65 años, se calculó el tamaño de la muestra en 357 pacientes. La información recolectada fue almacenada en el programa excel versión 2013 y analizada en EPI INFO versión 7.1.4. Resultados: la mediana de edad fue 75 años, el género masculino 52,66%, el promedio de medicamentos por paciente fue de 8,77 con una DE +/- 5. El diagnóstico más frecuente fue insuficiencia cardiaca con 29 casos (8,12 %). La prescripción inapropiada de medicamentos (PIM) según los criterios Beers, se observó en 4,9%, los más frecuentes fueron metoclopramida 20% y amiodarona 14%. La lista PRISCUS identificó 2.5% de prescripciones inapropiadas siendo prazosin (20%) el más relacionado. Conclusiones: los medicamentos encontrados según los criterios BEERS fueron metoclopramida, amiodarona, prazosina, betametildigoxina y con los PRISCUS, prazosina, haloperidol, betametildigoxina y difenhidramina.


Introduction: inappropriate drug prescribing is defined as the use of medicines whose risks outweigh their benefits, or when there is increased potential of drug-drug interactions. The Beers and PRISCUS criteria were developed as tools to prevent potentially inappropriate medication (PIM) in the elderly. Objective: to identify PIM in the elderly population who attended the internal medicine service of Hospital Universitario Hernando Moncaleano Perdomo, by means of the Beers and PRISCUS criteria. Materials and methods: a descriptive, observational, cross-sectional study in patients over age 65. The sample size was calculated in 357 patients. Excel version 2013 was used for data storage. EPI INFO version 7.1.4 was used for data analysis. Results: mean age 75 years, males 52.66%, average number of drugs per patient 8.77 (SD +/- 5). Heart failure was the most common diagnosis (29 cases - 8.12 %). According to the Beers criteria, PIM was identified in 4.9% of patients; metoclopramide (20%) and amiodarone (14%) being the most prescribed. The PRISCUS list identified PIM in 2.5%; prazosin (20%) being the most prescribed. Conclusions: the drugs identified by the BEERS criteria were metoclopramide, amiodarone, prazosin, and beta-methyl digoxin. Prazosin, haloperidol, beta-methyl digoxin, and diphenhydramine were identified by the PRISCUS criteria.


Subject(s)
Humans , Aged , Aged, 80 and over , Aged
9.
Rev. Finlay ; 12(3)sept. 2022.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1406851

ABSTRACT

RESUMEN La esquizofrenia es probablemente el trastorno más enigmático y trágico que tratan los psiquiatras, y quizás, el más devastador. Se manifiesta en la juventud, por lo que los pacientes esquizofrénicos normalmente viven muchos años después del inicio de la enfermedad y continúan padeciendo sus efectos sin poder llevar una vida completamente normal. Se realizó una revisión bibliográfica para la cual se emplearon los recursos disponibles en Infomed, específicamente en las bases de datos EBSCO, SCIELO y libros de textos de autores cubanos y extranjeros. Se aplicó el método analítico-sintético y se revisaron 18 artículos científicos. Se expusieron los elementos que abordan el desarrollo histórico- cultural de la esquizofrenia desde la perspectiva de la ciencia, la tecnología y la sociedad. Se realizó esta revisión con el objetivo de contribuir al conocimiento sobre el desarrollo histórico cultural de la esquizofrenia, teniendo en cuenta las teorías que ha desarrollado el hombre a través de la ciencia para explicar la aparición de la enfermedad y la importancia de los factores sociales en la aparición, evolución y rehabilitación de este padecimiento.


ABSTRACT Schizophrenia is probably the most enigmatic and tragic disorder that psychiatrists treat, and perhaps the most devastating. It manifests itself in youth, so schizophrenic patients usually live many years after the onset of the disease and continue to suffer from its effects without being able to lead a completely normal life. A bibliographic review was carried out using the resources available in Infomed, specifically in the EBSCO and SCIELO databases and textbooks by Cuban and foreign authors. The analytical-synthetic method was applied and 18 scientific articles were reviewed. The elements that address the historical-cultural development of schizophrenia from the perspective of science, technology and society were exposed. This review was carried out with the aim of contributing to the knowledge about the historical cultural development of schizophrenia, taking into account the theories that man has developed through science to explain the appearance of the disease and the importance of social factors in the appearance, evolution and rehabilitation of this condition.

10.
Rev. Finlay ; 12(3)sept. 2022.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1406861

ABSTRACT

RESUMEN Fundamento: durante la evolución de la diabetes mellitus pueden aparecer complicaciones crónicas que afectan la esperanza y la calidad de vida relacionadas con la salud por lo que se perjudica la salud física y mental de los pacientes. Objetivo: determinar el comportamiento de la depresión en pacientes con diagnóstico de diabetes mellitus del consultorio médico de la familia #21 del municipio Rodas provincia Cienfuegos. Métodos: se realizó un estudio descriptivo de corte transversal, en el período de mayo de 2020 a mayo de 2021, el universo y la muestra estuvieron en correspondencia con los 36 pacientes diabéticos dispensarizados en el consultorio, a los que se les aplicó una encuesta y el Inventario de Depresión Rasgo-Estado. Se estudiaron las variables: edad, sexo, tipo de tratamiento, síntomas de depresión, complicaciones y nivel de depresión. El análisis y procesamiento de la información se hizo mediante el paquete estadístico SPSS versión 15 para Windows, los resultados se expresaron en números y porcientos. Resultados: predominó el sexo femenino en un 58,3 %, el grupo etáreo más representado fue el de 48-57 (50 %). Predominó el grupo de pacientes que consumen hipoglicemiantes orales (55 %). Hubo prevalencia de los pacientes con depresión (72,2 %), siendo más frecuente los que reciben tratamiento con hipoglicemiantes orales (47,2) y existió una elevada incidencia en el sexo femenino (41,6 %). Predominaron los pacientes con complicaciones renales (19,4 %) y cardiovasculares (16,6 %). El 75 % de los pacientes presentaron depresión baja. Conclusiones: en el estudio predominó el sexo femenino y el grupo etáreo de 48-57 años. Existió una prevalencia elevada de las complicaciones asociadas a la aparición de depresión y el consumo de hipoglicemiantes orales. Más de la mitad de los pacientes estudiados presentaron síntomas manifiestos de depresión. Prevalecieron los pacientes que presentaron depresión baja.


ABSTRACT Background: during the evolution of diabetes mellitus, chronic complications may appear that affect life expectancy and health-related quality of life, thus harming the physical and mental health of patients. Objective: to determine the behavior of depression in patients diagnosed with diabetes mellitus of the Family Medical Office #21 of the Rodas municipality, Cienfuegos province. Methods: a descriptive cross-sectional study was carried out, in the period from May 2020 to May 2021, the universe and the sample were in correspondence with the 36 diabetic patients dispensed in the office, to whom a survey was applied and the Adult Depression Test. The variables were studied: age, sex, type of treatment, symptoms of depression, complications, level of depression. The analysis and processing of the information was done using the statistical package SPSS version 15 for Windows, the results were expressed in numbers and percentages. Results: predominance of the female sex in 58.3 %, the most represented age group is that of 48-57 (50 %). The group of patients consuming oral hypoglycemic drugs (55 %) predominated. There was a prevalence of patients with depression (72.2 %), being more frequent those receiving treatment with oral hypoglycemic agents (47.2) and there was a high incidence in females (41.6 %). Patients with renal (19.4 %) and cardiovascular (16.6 %) complications predominated. 75 % of the patients presented low depression. Conclusions: the female sex and the age group of 48-57 predominated in the study. There was a high prevalence of complications associated with the appearance of depression and the consumption of oral hypoglycemic agents. More than half of the patients studied presented manifest symptoms of depression. Patients who presented low depression prevailed.

11.
Rev. chil. nutr ; 49(1)feb. 2022.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1388576

ABSTRACT

RESUMEN En esta investigación, con el método de superficie de respuesta (33), se determinó la máxima retención de ácido ascórbico en papa Puka Ambrosio sometida a fritura. Se ensayó con 160, 170 y 180 °C; 150, 180 y 210 segundos; 2, 3 y 4 mm de espesor de hojuela. Se retuvo 87,3% de ácido ascórbico en hojuelas de 2 mm de espesor sometidas a 170 °C y 200 segundos de fritura. El espesor y la interacción entre este y el tiempo tuvieron efecto significativo (p<0,05) sobre la retención. La papa y la hojuela frita tuvieron respectivamente en promedio: 21,0±1,6 y 18,4±2,9 mg/100 g de ácido ascórbico; 27,1 ± 2,1 y 21,1 ± 3,3 mg/100 g de vitamina C en base seca desgrasada; 69,0±0,03 y 22,2±0,03% de humedad; 1±0,09 y 21,9±0,03 de grasa cruda en base seca; y 332±97 y 597±22 mg de ácido clorogénico equivalente/100 g de compuestos fenólicos totales; 6424±57 y 8309±80 μg de equivalente Trolox/g de capacidad antioxidante; y 58,1±1,7 y 33,6±5,0 mg de cianidina-3-glucósido equivalente/100 g de antocianinas totales, todas medidas en base seca desgrasada. La operación de fritura generó modificaciones en las características físicas, químicas, concentración de componentes bioactivos y capacidad antioxidante, observándose un incremento en el contenido de carbohidratos, fibra, cenizas, compuestos fenólicos y capacidad antioxidante.


ABSTRACT In this research, the maximum retention of ascorbic acid was determined in the Puka Ambrosio potato subjected to frying using the response surface method (33). Retention was tested at 160, 170 and 180 °C for 150, 180 and 210 seconds and with a flake thickness of 2, 3 and 4 mm. In 2 mm flakes at 170 °C and 200 seconds of frying, 87.3% ascorbic acid was retained. Flake thickness and the interaction between thickness and frying time had a significant effect (p<0.05) on retention. The potato and its fried flakes had on average: 21.0±1.6 and 18.4±2.9 mg/100 g of ascorbic acid, respectively; and 7.1±2.1 and 21.1±3.3 mg/100 g of vitamin C on a defatted dry basis; 69±0.03 and 22.2±0.03 percent moisture; 1±0.09 and 21.9±0.03 of crude fat on dry basis; 332±97; and 597±22 mg of chlorogenic acid equivalent/100 g of total phenolic compounds; 6424±57 and 8309±80 μg of Trolox equivalent/g of antioxidant capacity; and 58.1±1.7 and 33.6±5.0 mg of cyanidin-3-glucoside equivalent /100 g of total anthocyanins on a defatted dry basis. The frying operation generated modifications in the physical-chemical characteristics, of bioactive component concentration and in the antioxidant capacity. We observed an increase in the content of carbohydrates, fiber, ash, phenolic compounds and antioxidant capacity.

15.
World J Hepatol ; 12(12): 1299-1313, 2020 Dec 27.
Article in English | MEDLINE | ID: mdl-33442456

ABSTRACT

BACKGROUND: The implementation of nutritional strategies targeting several variables at once could benefit patients with cirrhosis. Non-alcoholic beer has different compounds that exert antioxidant, anti-inflammatory and nutritional properties. AIM: To evaluate the effect of diet + exercise and non-alcoholic beer on nutritional status, endothelial function and quality of life in patients with cirrhosis. METHODS: In this randomized open clinical trial, patients with cirrhosis were randomized into two groups: The intervention (non-alcoholic beer + diet + exercise) and control (water + diet + exercise) group. Treatment consisted of 330 mL non-alcoholic beer/day or the same amount of water, plus an individualized dietary plan and an exercise program with a pedometer-based bracelet to reach at least 5000 steps/d and > 2500 above the baseline during 8 wk. Endothelial function (flow-mediated dilation, plethysmography), biochemical and nutritional variables and quality of life (CLDQ) were evaluated. RESULTS: Forty-three patients were included in the study, 21 in the control group and 22 in the intervention group. The mean age was 53.5 ± 7.8 years, 60% were women, the median MELD score was 8 (7-10) and most patients were Child-Pugh A (88%). Adherence to the interventions was > 90% in both groups, there were no adverse events and all biochemical parameters remained stable in both groups. Endothelial function improved in both groups. All measured nutritional parameters improved in the intervention group, compared to only 2 in the control group and quality of life improved in both groups; however, more domains improved in the intervention group. CONCLUSION: The intervention consisting of non-alcoholic beer, diet and exercise seems to be safe and well tolerated in patients with cirrhosis, and shows improvement in nutritional status, endothelial function, and quality of life. These results need to be further confirmed.

16.
Rev. cienc. salud (Bogotá) ; 17(1): 70-84, ene.-abr. 2019. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1013860

ABSTRACT

Resumen Introducción: la Terapia Ocupacional impacta positivamente en la salud y el bienestar al realizar, por medio de la ocupación, acciones específicas en la Unidad de Cuidado Intensivo (UCI) en las que se abordan la rehabilitación y recuperación de habilidades. Materiales y métodos: estudio aplicado a terapeutas ocupacionales con mínimo de 2 años de experiencia clínica y 1 año en Unidad de Cuidado Intensivo Adulto en Colombia, en el periodo de diciembre de 2016 a marzo de 2017. Se analizaron categorías específicas encaminadas al conocimiento basado en participación, experiencia, evaluación, intervención y retos. Resultados: participaron 20 terapeutas experimentados en diferentes categorías: (a) Participación: como ejecutores, el 70 %, y el 55 % hace parte de intervención temprana en rehabilitación. (b) Experiencia: se evidencia atención de entidades clínicas más referenciadas, se hace uso de modelos y marcos teórico-prácticos reconocidos y difundidos. (c) Evaluación: se realiza en áreas cognitiva y Actividades de la Vida diaria, usando instrumentos como historia ocupacional y observación. (d) Intervención: énfasis en modalidades y medios de intervención encaminados a las Actividades de la Vida diaria, Cognitivo, Sensorial y Trabajo con Familias. (e) Retos: dividido en fortalezas y dificultades donde se expresaron beneficios, problemáticas y otros. Conclusión: se identifican y analizan acciones del terapeuta ocupacional colombiano en las UCI, correlacionándose con los reportes a nivel internacional. Se resalta la participación en los equipos de intervención temprana, sus acciones con las familias y sus acciones centradas en la ocupación.


Abstract Introduction: Occupational Therapy positively impacts on health and well-being by performing, through occupation, specific actions in the Intensive Care Unit (ICU) in which rehabilitation and recovery of skills are addressed. Materials and methods: study applied to occupational therapists with a minimum of 2 years of clinical experience and 1 year in the Adult Intensive Care Unit in Colombia, from December 2016 to March 2017. Specific categories aimed at knowledge based on participation, experience, evaluation, intervention and challenges. Results: 20 experienced therapists participated in different categories: (a) Participation: as executors, 70 %, and 55 % are part of early intervention in rehabilitation. (b) Experience: evidence of more referenced clinical entities is evidenced, models and recognized theoretical and practical frameworks are used and disseminated. (c) Evaluation is done in cognitive areas and Activities of Daily Life, using instruments such as occupational history and observation. (d) Intervention: emphasis on modalities and means of intervention aimed at Activities of Daily, Cognitive, Sensory and Work with Families. (e) Challenges: divided into strengths and difficulties where benefits, problems and others were expressed. Conclusion: actions of the Colombian occupational therapist are identified and analyzed in the ICU, correlating with the reports at the international level. The participation in the early intervention teams, their actions with the families and their actions focused on the occupation are highlighted.


Resumo Introdução: a terapia Ocupacional impacta positivamente na saúde e o bem-estar através da ocupação realizando ações específicas na Unidade de Cuidado Intensivo abordando a reabilitação e recuperação de habilidades, enquadradas em processos de atenção ainda sem desenvolvimento. Analisar as ações que realiza uma terapeuta ocupacional em uma Unidade de Cuidado Intensivo Adulto na Colômbia. Materiais e métodos: estudo misto aplicado a Terapeutas ocupacionais, com mínimo 2 anos de experiência clínica e 1 ano em Unidade de Cuidado Intensivo adulto na Colômbia; no período dezembro 2016 - março 2017. Analisaram-se categorias específicas encaminhadas ao conhecimento baseado em: participação, experiência, avaliação, intervenção e desafios. Resultados: participaram 20 terapeutas experimentados. Respeito às categorias: (a) Participação: como executores de 70 % e o 55 % faz parte de intervenção precoce de reabilitação. (b) Experiência: tempo mínimo de 1 ano na unidade; se evidencia atenção de entidades clínicas mais referenciadas; se faz uso de modelos e marcos teórico-práticos reconhecidos e difundidos. (c) Avaliação: se realizam em áreas cognitivas e Atividade da vida diária, usando instrumentos como História ocupacional e Observação. (d) Intervenção: ênfase, modalidade e meios de intervenção encaminhados às atividades da vida diária, Cognitivo, Sensorial e Trabalho com famílias. (e) Desafios: dividido em fortalezas e dificuldades onde se expressaram benefícios, problemáticas e outros. Conclusão: se identificam e ratificam ações do terapeuta ocupacional colombiano nas UCI, correlacionando-se com os reportes a nível internacional. Ressalta-se a participação nas equipes de intervenção precoce, suas ações com as famílias e suas ações centradas na ocupação. Esta pesquisa aporta e fortalece o conhecimento nesta área específica e convida à construção de novas propostas na intervenção clínica.


Subject(s)
Humans , Occupational Therapy , Rehabilitation , Health Personnel , Colombia
17.
Appl Soil Ecol, v. 143, p. 181-191, nov. 2019
Article in English | Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP | ID: bud-2827

ABSTRACT

The edaphic fauna plays an important role in the organic matter dynamics of the soil. Millipeds (Diplopoda),centipeds (Chilopoda) and isopods (Isopoda) are among the main components of the soil fauna. Vegetationstructure represents one of the main factors influencing composition and diversity of these species that inhabitleaf litter and soil, what is particularly important in the Amazon Forest, where there are several singular ve-getation types. Savannah and forest areas stand out in ferruginous hills, which represents one of the most poorlyknown and highly threatened ecosystems in the Amazon. However, sampling the edaphic fauna in high diversitysites represents a challenging task. Studies have shown that sampling method may influence observed patterns ofdiversity. From this perspective, the present study aimed to (i) investigate whether assemblages of Chilopoda,Diplopoda and Isopoda differ between vegetation types in the Amazon, (ii) indicate how biological parametersbehave in such communities, (iii) identify which method or combination of methods is better suited to samplespecies richness and (iv) quantify the efficiency of each method regarding time of work and cost. Sampling wasconducted by means of hand collection, leaf litter collection, hay-bait traps and soil sampling in four patches,two in the savannah (also called canga) and two in the forest. Richness was higher in forest habitats forChilopoda and Diplopoda, while for Isopoda there was no significant difference. Species composition also dif-fered between vegetation types for Chilopoda and Isopoda, but not for Diplopoda. Beta diversity between ve-getation types was mainly determined by nestedness and balancing, while turnover was the main beta diversitycomponent responsible for differences among methods. Soil sampling and hand collection added more species tothe samples, therefore, this combination was the most efficient to access diversity. Our results support thehypothesis that differences in the soil cover promoted by distinct vegetation types influence the species diversityand composition of edaphic fauna. The differences were mainly determined by nestedness and balancing, in-dicating that the fauna sampled in the canga represents a subset of those present in the surrounding forest. In thissense, even in ecosystems with distinct vegetation types, the combination of soil and surface sampling methods isrecommended. Lastly, the present study proposes a set of decision rules and a key to select the most appropriatemethod to sample the studied taxonomic groups

18.
Appl soil ecol ; 143: 181-191, 2019.
Article in English | Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP | ID: but-ib17176

ABSTRACT

The edaphic fauna plays an important role in the organic matter dynamics of the soil. Millipeds (Diplopoda),centipeds (Chilopoda) and isopods (Isopoda) are among the main components of the soil fauna. Vegetationstructure represents one of the main factors influencing composition and diversity of these species that inhabitleaf litter and soil, what is particularly important in the Amazon Forest, where there are several singular ve-getation types. Savannah and forest areas stand out in ferruginous hills, which represents one of the most poorlyknown and highly threatened ecosystems in the Amazon. However, sampling the edaphic fauna in high diversitysites represents a challenging task. Studies have shown that sampling method may influence observed patterns ofdiversity. From this perspective, the present study aimed to (i) investigate whether assemblages of Chilopoda,Diplopoda and Isopoda differ between vegetation types in the Amazon, (ii) indicate how biological parametersbehave in such communities, (iii) identify which method or combination of methods is better suited to samplespecies richness and (iv) quantify the efficiency of each method regarding time of work and cost. Sampling wasconducted by means of hand collection, leaf litter collection, hay-bait traps and soil sampling in four patches,two in the savannah (also called canga) and two in the forest. Richness was higher in forest habitats forChilopoda and Diplopoda, while for Isopoda there was no significant difference. Species composition also dif-fered between vegetation types for Chilopoda and Isopoda, but not for Diplopoda. Beta diversity between ve-getation types was mainly determined by nestedness and balancing, while turnover was the main beta diversitycomponent responsible for differences among methods. Soil sampling and hand collection added more species tothe samples, therefore, this combination was the most efficient to access diversity. Our results support thehypothesis that differences in the soil cover promoted by distinct vegetation types influence the species diversityand composition of edaphic fauna. The differences were mainly determined by nestedness and balancing, in-dicating that the fauna sampled in the canga represents a subset of those present in the surrounding forest. In thissense, even in ecosystems with distinct vegetation types, the combination of soil and surface sampling methods isrecommended. Lastly, the present study proposes a set of decision rules and a key to select the most appropriatemethod to sample the studied taxonomic groups

19.
Rev. med. Risaralda ; 23(2): 23-28, jul.-dic. 2017. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-902076

ABSTRACT

Objetivo: Caracterizar clínica paraclínica y epidemiológicamente el Lupus Eritematoso Sistèmico en los pacientes del Hospital Universitario Hernando Moncaleano Perdomo de Neiva Diseño: Descriptivo de corte transversal. Población: Pacientes atendidos en el Hospital Universitario de Neiva Hernando Moncaleano Perdomo con diagnóstico de lupus eritematoso sistèmico. Método: Recolección de datos a través de revisión documental de historias clínicas del Hospital Universitario de Enero 2009 a Enero 2014. Resultados: De un total de 104 pacientes con lupus eritematoso sistèmico encontrados en el periodo de estudio, la relación mujer: hombre fue de 5:1. Las comorbilidades de mayor frecuencia en el género femenino fueron la hipertensión arterial con un 26,7%, la fibromialgia con 12,7% y el síndrome de antifosfolípidos con 12, 7%; en el género masculino la hipertensión arterial, la fibromialgia y la falla cardiaca se presentaron cada una en un 27,7%. El 61,5% de las pacientes femeninas tuvieron manifestaciones en piel, el 51,1% refirieron artralgias y solo un 25,5% presentaron compromiso articular caracterizado por derrame sinovial. En los hombres las manifestaciones en piel estuvieron presentes en un 50%, las artralgias y el compromiso articular caracterizado por derrame sinovial fueron un 50% y 22,2% respectivamente. En los exámenes paraclínicos entre el 12,7% y el 31,4% de los pacientes tenían un lupus activo, determinado por la presencia de leucopenia, proteinuria y C3-C4 consumidos. En la muestra de pacientes femeninas las alteraciones paraclínicas más frecuentes se caracterizaron por hemoglobina <12 g/dl en 53,4% y trombocitopenia en 26,7%. Por su parte, 33,3% de los hombres presentaron trombocitopenia y 6,3% hemoglobina <12 g/dl.


Objective: To characterize clinically, paraclinical, and epidemiologically Systemic Lupus Erythematosus in patients at Hospital Universitario in Neiva Design: Descriptive cross sectional. Place: Hospital Universitario Hernando Moncaleano Perdomo, Neiva-Colombia. Population: Patients at Hospital Universitario Hernando Moncaleano Perdomo with diagnosis of Systemic Lupus Erythematosus. Method: Data collection of medical histories was performed. Results: Of 104 medical histories, the disease occurs five times more often in women than in men (ratio of 5:1). The most frequent comorbidities in females were hypertension with 26.74%, fibromyalgia and anti-phospholipid syndrome both with 12, 79%; In male patients hypertension, fibromyalgia and heart failure were presented each in a 27.78%. 61.53% of female patients had skin manifestations, 51.16% reported arthralgia and only 25.58% had joint involvement characterized by synovial effusion; in men skin manifestations were 50%, 50% arthralgia and articular involvement characterized by synovial effusion was 22.22%. In the laboratory test between 12.79% and 31.40% of patients had active lupus, determined by the presence of leukopenia, proteinuria and C3 and C4 consumed. In the sample of female patients the most frequent paraclinical alterations were characterized by hemoglobin <12 g / dl in 53.48% and 26, 74% of patients present thrombocytopenia. Meanwhile, 33.33% of men had thrombocytopenia and 6.38% had hemoglobin <12 g / dl.


Subject(s)
Humans , Male , Female , Adult , Epidemiology , Antiphospholipid Syndrome , Leukopenia , Lupus Erythematosus, Systemic , Patients , Proteinuria , Skin Manifestations , Thrombocytopenia , Hemoglobins , Fibromyalgia , Arthralgia , Laboratory Test , Joints
20.
Acta Med Port ; 30(7-8): 568-572, 2017 Aug 31.
Article in Portuguese | MEDLINE | ID: mdl-28926331

ABSTRACT

INTRODUCTION: The urinary incontinence can affect up to 50% of women at some stage of their lives, particularly during pregnancy and postpartum. This study was designed in order to identify and assess the prevalence and risk factors for urinary incontinence during the third trimester of pregnancy and three months postpartum. MATERIAL AND METHODS: Observational and cross-sectional study. The population of the study was composed of 268 women who delivered and were admitted to the Centro Hospitalar Tâmega e Sousa in the years 2013 and 2014, and who agreed to participate in this study. Postpartum women were asked to fill out a questionnaire adapted from the International Consultation on Incontinence Questionnaire - Short Form, for urinary incontinence research in the third trimester of pregnancy. Three months after delivery, they were contacted by telephone and asked to answer the same questions about the urinary incontinence postpartum. RESULTS: Of the 268 women interviewed, 31 were excluded from the study, taking into account the defined inclusion and exclusion criteria. In total (n = 237), 51.89% of women included in the study, reported the occurrence of urinary incontinence during pregnancy. The prevalence of urinary incontinence in pregnancy by parity (primiparous versus multiparous) was statistically significant (p = 0.006). At postpartum (n = 237), 28.69% of women with urinary incontinence had vaginal delivery and 5.91% of women underwent cesarean delivery (p = 0.001). In these group of women with postpartum urinary incontinence (n = 82), 31.69% have had urinary incontinence only in the postpartum and 68.31% of women have had symptoms during pregnancy (p < 0.001). DISCUSSION: This study demonstrates the high prevalence of urinary incontinence in pregnancy and the respective decrease in postpartum. CONCLUSION: Multiparity and occurrence of urinary incontinence in pregnancy appear as potential risk factors in the emergence of the urinary incontinence.


Introdução: A incontinência urinária pode afetar até 50% das mulheres em alguma fase das suas vidas, nomeadamente durante a gravidez. Este estudo foi desenhado com a finalidade de identificar e avaliar a prevalência e fatores de risco para incontinência urinária durante o terceiro trimestre da gravidez e três meses após o parto. Material e Métodos: Estudo observacional e transversal. A população do estudo incluiu 268 puérperas, que tiveram parto no Centro Hospitalar Tâmega e Sousa, em 2013 e 2014. Foram avaliadas durante o período de internamento após o parto. As parturientes foram convidadas a preencher um questionário adaptado, International Consultation on Incontinence Questionnaire - Short Form, para investigação da incontinência urinária no terceiro trimestre da gravidez, para o qual deram consentimento. Três meses após o parto, foram contactadas telefonicamente e convidadas a responder às mesmas questões acerca da incontinência urinária no pós-parto. Resultados: Das 268 mulheres entrevistadas, 31 foram excluídas do estudo, tendo em conta os critérios de inclusão e exclusão definidos. No total (n = 237), 51,89% das mulheres incluídas no estudo, relataram a ocorrência de incontinência urinária durante a gravidez. A prevalência da incontinência urinária na gravidez, segundo a paridade (primíparas versus multíparas), foi estatisticamente significativa (p = 0,006). No pós-parto (n = 237), 28,69% das mulheres com incontinência urinária tiveram parto vaginal e 5,91% das mulheres foram submetidas a cesariana (p = 0,001). Neste grupo de mulheres com incontinência urinária pós-parto (n = 82), 31,69% apresentaram incontinência urinária de novo e 68,31% das mulheres já apresentavam sintomatologia durante a gravidez (p < 0,001). Discussão: Este estudo demonstra a elevada prevalência da incontinência urinária na gravidez e a respetiva redução no pós-parto. Conclusão: A multiparidade e a ocorrência de incontinência urinária na gravidez surgem como possíveis fatores de risco no aparecimento da incontinência urinária.


Subject(s)
Pregnancy Complications/epidemiology , Puerperal Disorders/epidemiology , Urinary Incontinence/epidemiology , Adult , Cross-Sectional Studies , Female , Humans , Pregnancy , Prevalence
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