ABSTRACT
A case report of a 18 years-old women on her first pregnancy, (26 weeks). US detected a live fetus with pulmonary sequestration diagnosis. On week 39 vaginal delivery occurred. A live newborn, Apgar 7-8 and Silverman 4-4 (one minute and five minutes respectively) was obtained. When diagnoses was confirmed, a surgical resection was performed (five days) and the child died at day-15 due to nosocomial sepsis. This case shows the convenience of prenatal diagnosis for management decisions.
Subject(s)
Bronchopulmonary Sequestration/diagnostic imaging , Ultrasonography, Prenatal , Adolescent , Female , Gestational Age , Humans , Infant, Newborn , Male , PregnancyABSTRACT
OBJECTIVE: To determine the efficacy of erythropoietin in very low birth weight (VLBW) newborns less than 72 h of age. PATIENTS AND METHODS: We randomly assigned 40 critically ill newborn VLBW infants to receive either recombinant human erythropoietin (EPO) 150 units/kg per day (21 patients) or placebo (19 patients) during their first six weeks of life. The observers were unaware of the treatment assignments. Frequency of erythrocyte transfusion, adverse effects and haematologic measures were evaluated and compared. RESULTS: Before treatment gestational age, weight, haemoglobin, and pathology were similar in both groups. During the subsequent 6 weeks, haemoglobin and haematocrit of the placebo group fell significantly below those of the EPO recipients. More transfusions were received by the placebo recipients (7/21) than by the EPO recipients (2/21; p = 0.04). No adverse effects of EPO were observed. CONCLUSIONS: We recommend the administration of recombinant human erythropoietin since the first 72 h of age, because of the high frequency of anaemia, the efficacy of EPO and lack of side effects.
Subject(s)
Anemia/prevention & control , Critical Care , Erythropoietin/therapeutic use , Infant, Premature , Infant, Very Low Birth Weight , Drug Administration Schedule , Erythrocyte Transfusion/statistics & numerical data , Erythropoietin/administration & dosage , Hematocrit , Hemoglobins/analysis , Humans , Infant, Newborn , Recombinant Proteins/administration & dosage , Recombinant Proteins/therapeutic use , Treatment OutcomeABSTRACT
OBJECTIVE: To alert about an unusual and poorly informed entity, with high mortality. That should be considered in critically ill neonates with central venous catheter and parenteral nutrition, in order to establish early diagnosis and treatment. CASE REPORT: Two neonates, one born at term and the other premature, with central venous catheter and parenteral nutrition. They had sudden unexplained hypotension and signs of decompensation and death secondary to cardiac tamponade. DISCUSSION: Cardiac tamponade secondary to central venous catheter is an unusual entity seldom discussed in the literature. The estimated incidence is 0.3 to 2% with a 74 to 100% mortality. It must be suspected and diagnosed early in order to decrease the mortality.
Subject(s)
Cardiac Tamponade/etiology , Catheterization, Central Venous/adverse effects , Infant, Premature, Diseases/etiology , Parenteral Nutrition , Cardiac Tamponade/diagnostic imaging , Female , Humans , Infant, Newborn , Infant, Premature, Diseases/diagnostic imaging , Male , Radiography, ThoracicABSTRACT
Primary cardiac tumors are very infrequent at all ages; the most frequent in the pediatric age is rhabdomyoma. This tumor is associated with tuberous sclerosis in 37 to 80%, with a frequency of 1 for each 40,000 live newborns. This case is about a newborn, who in the immediate postnatal period presented pansystolic murmur, grade IV cardiomegaly, electrocardiographic changes of biventricular hypertrophy and heart failure. Echocardiogram and magnetic resonance images showed several tumors in the septum and in ventricular walls; histopathology study of the heart, confirmed the diagnosis. The diagnosis of tuberous sclerosis was made clinically (seizures, hypomelanotic macules) and with the image of parenchymal hypodense areas. In our country there is little information about both diseases, that's why we made a review of the incidence, diagnosis, prognosis and treatment.
Subject(s)
Heart Neoplasms/pathology , Rhabdomyoma/pathology , Heart Neoplasms/diagnostic imaging , Humans , Infant, Newborn , Male , Rhabdomyoma/diagnostic imaging , Tomography, X-Ray Computed , UltrasonographyABSTRACT
Through participation of ten hospital institutions in the city of San Luis Potosí, which systematically take care of newborns, the present collaborative study was performed; this includes all births during the period from january 1st. to december 31st., 1988. The births taken place at home and other sites such as the "Hospital Materno Infantil" during the last six months, were excluded from the study; they accounted approximately 10%. We registered 17,092 births including 204 mortinates. Based on the upper data, the following chart is given, stating weight as well as gestation rates. Precocious fetal mortality (500 to 999 g)--391.30 by thousand; Precocious fetal mortality (20 to 27 weeks)--140.40 by thousand; Late fetal mortality (1,000 g or more)--9.25 by thousand; Late fetal mortality (28 weeks or more)--9.89 by thousand; Hebdomadal mortality (500 to 999 g)--571.40 by thousand; Hebdomadal mortality (20 to 27 weeks)--159.40 by thousand; Hebdomadal mortality (1,000 g or more)--11.96 by thousand; Hebdomadal mortality (28 weeks or more)--12.62 by thousand; Perinatal mortality (1,000 g or more)--21.10 by thousand; Perinatal mortality (28 weeks or more)--22.38 by thousand. The IMSS sent for registration 8,710 births which accounted 51% of the total. Their data revealed the highest values in all rates. In precocious fetal mortality (products between 20 and 27 weeks), the rate value was 543.9 against 140.4 globally counted. Hebdomadal mortality for this 20 to 27 weeks group showed 730.8 against 159.4 globally reported. In 199 out the 204 mortinates, cause of death was registered; 49.7% of these causes was reported as placental circulation insufficiency and 17.1% as major congenital abnormalities.(ABSTRACT TRUNCATED AT 250 WORDS)