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2.
N Engl J Med ; 292(14): 722-5, 1975 Apr 03.
Article in English | MEDLINE | ID: mdl-1113781

ABSTRACT

The concept that hysterectomy is of value in the management of septic abortion induced by instillation of soap or phenolic antiseptics into the uterus is challenged. Nineteen out of 20 such cases with renal failure were managed with intensive antibiotic therapy, peritoneal dialysis and an absolute minimun of surgical intervention. Seventeen patients recovered, with normal renal function. Of the 11 known to be subsequently exposed to conception seven have achieved normal pregnancies.


PIP: 20 cases of septic abortion were reviewed, all of which had suffered septic shock and renal failure attributed to intrauterine instillation of soap or phenolic antiseptic solutions, which were treated at Hammersmith Hospital from 1965-1972 to determine proper management of such patients. 19 were managed conservatively, from a surgical point of view, with 13 not even having the products of conception removed from the uterus. Intensive antibiotic treatment and peritoneal dialysis were the principles of management. 17 of the 19 recovered; all 17 retain normal renal function. Of these 17 survivors, 7 have had normal pregnancies, but only 11 of the 17 have been exposed to conception.


Subject(s)
Abortifacient Agents/adverse effects , Abortion, Septic/therapy , Acute Kidney Injury/complications , Abortion, Criminal , Abortion, Septic/complications , Abortion, Septic/diet therapy , Abortion, Septic/surgery , Adolescent , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Anti-Infective Agents, Local/adverse effects , Female , Hematologic Diseases/complications , Humans , Hysterectomy , Infant, Newborn , Kidney Failure, Chronic/diet therapy , Peritoneal Dialysis , Phenols/adverse effects , Pregnancy , Soaps/adverse effects , Uterus
3.
Br J Pharmacol ; 40(3): 558P, 1970 Nov.
Article in English | MEDLINE | ID: mdl-5497819
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