Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 88
Filter
1.
Revue Africaine de Médecine Interne ; 10(1-2): 26-32, 2023. tables
Article in French | AIM (Africa) | ID: biblio-1511811

ABSTRACT

Contexte : la maladie thyroïdienne représente la plus fréquente endocrinopathie dans le monde après le diabète sucré. En Afrique, elle constitue un véritable problème de santé publique et sa prise en charge est souvent entravée par les moyens d'investigations. Le but était d'étudier le profil des affections thyroïdiennes à Bouaké. Méthodes : il s'agissait d'une étude rétrospective, descriptive, menée dans le service de consultation de Médecine Interne du Centre Hospitalier Universitaire de Bouaké du 1er janvier 2020 au 31 décembre 2021. Elle a porté sur les dossiers de 104 patients suivis pour une pathologie thyroïdienne. Résultats : Sur 2560 patients reçus, la pathologie thyroïdienne concernait 104 patients ; soit une fréquence de 4,1%. Il s'agissait de 93 femmes et 11 hommes avec un sex-ratio (H/F) de 0,12 L'âge moyen était de 42,03 ans ±15 ans. Dans plus de la moitié des cas (55,8%), le délai de consultation était supérieur à 06 mois. Sur le plan fonctionnel, 58 patients (55,8%) présentaient une hyperthyroïdie avec comme principales étiologies la maladie de Basedow (60,3%, n=35) et le goitre multinodulaire toxique (24,1%, n=14). L'hypothyroïdie était retrouvée chez 10 patients (9,6%), le plus souvent post thyroïdectomie (60%). Les goitres et nodules euthyroïdiens étaient retrouvés chez 36 patients (34,6%) dominés par le goitre multinodulaire euthyroïdien (36,1%, n=13) et le goitre simple (27,8%, n=10). Le traitement des hyperthyroïdies reposait essentiellement sur les antithyroïdiens de synthèse dans 96,7%. Seulement 1 patient hyperthyroïdien avait subi une thyroïdectomie. La majorité des patients (82,2%) étaient perdus de vue. Conclusion : La pathologie thyroïdienne au CHU de Bouaké est une maladie fréquente de la femme jeune. Les hyperthyroïdies dominent le tableau des thyréopathies avec comme principale étiologie la maladie de Basedow. On note un taux élevé de perdu de vue, d'où l'intérêt d'une éducation de nos patients.


Context: Thyroid disease is the most common endocrinopathy observed in the world. In Africa, thyroid diseases remain a real public health problem and their care is often hampered by the means of investigation. The purpose of this work was to study the profile of thyroid affections in Bouake. Methods: This was a descriptive study with retrospective data collection, carried out over the period from 1 January 2020 to 31 December 2021 at the Internal Medicine consultation at the University Hospital of Bouake. All epidemiological, clinical and therapeutic and evolutionary data from patients followed for thyroid pathology were collected. It focused on the records of 104 patients followed for thyroid disease. Results: Out of a total of 2560 consultations, 104 patients were involved in thyroid pathology, prevalence of 4.1%. They were 93 women and 11 men with a sex ratio of 0.12. The average age was 42.03±15.64 years. In more than half of the patients (55.8%) the evolution of the clinical symptomatology was more than six months. A total of 58 patients (55.8%) had hyperthyroidism. The etiologies of hyperthyroidism were dominated by Grave's disease and toxic multinodular goiter, with 60.3% and 24.1% of hyperthyroidism respectively. Hypothyroidism was confirmed in 10 patients (9.6%), among then 6 (60%) had undergone total thyroidectomy. The multinodular goiter was found in 36 patients and was dominated by multinodular goiter (36.1%) and single goiter (27.8%). The treatment of hyperthyroidism was exclusively with synthetic antithyroid drugs. Hypothyroidism was treated with hormone replacement therapy. The majority of patients (82.2%) were lost in view. Conclusion: The thyroid pathology at the University Hospital Center of Bouake is a frequent illness of the young woman. Hyperthyroidism were frequently found with as main etiology Grave's disease The majority of patients (82.2%) were lost in view hence the interest of patient's education.


Subject(s)
Thyroid Gland
2.
Revue Africaine de Médecine Interne ; 9(2-2): 19-25, 2022. figures, tables
Article in French | AIM (Africa) | ID: biblio-1433987

ABSTRACT

Objectif : déterminer les étiologies des fièvres prolongées inexpliquées au service de médecine interne du CHU de Bouaké. Matériel et méthodes : Il s'agissait d'une étude rétrospective à visée descriptive mené de janvier 2019 à décembre 2020. Nous avons inclus les patients hospitalisés pour fièvre prolongée inexpliquée ou ayant présentés une fièvre prolongée durant l'hospitalisation. Les données anamnestiques, cliniques et paracliniques ont été analysées. Résultats : Nous avons retenus 204 patients sur 1650 patients hospitalisés (12,6%). L'âge moyen des patients était de 32±16,1 ans avec des extrêmes de 16 et 87 ans. Le sexe ratio était de 1,1. La fièvre (32,4%) et AEG (22%) constituaient les motifs d'hospitalisation les plus fréquents. La fièvre était le plus fréquent des symptômes physiques (94,1%) suivi de l'amaigrissement (50%), de la déshydratation (18,1%), de l'hépatomégalie (12,7%) et de l'obnubilation (12%). Les principales étiologies étaient les infections (82,3%), les tumeurs (10,3%), et les maladies inflammatoires (1,5%). Dans 5,9% des cas l'étiologie n'avait pas été retrouvée. Les principales infections étaient le VIH et ses complications (38,1%), la tuberculose (21,4%), et les infections urogénitales (19,9%). Les tumeurs étaient dominées par le cancer primitif du foie (33,4%) et le cancer de la prostate (19,4%). La polyarthrite rhumatoïde, le lupus érythémateux disséminé et la sclérodermie étaient maladies inflammatoires retrouvées. La létalité était de 36%. Conclusion : Les étiologies des fièvres prolongées inexpliquées sont variées. Elles sont dominées dans notre contexte par la tuberculose, l'infection à VIH et ses complications infectieuses.


Subject(s)
Humans , Male , Female , Arthritis, Rheumatoid , Prostatic Neoplasms , Scleroderma, Localized , Signs and Symptoms , Tuberculosis , Fever of Unknown Origin , Lupus Erythematosus, Systemic , Neoplasms , Fever
3.
Revue Africaine de Médecine Interne ; 9(2-2): 30-35, 2022. tables
Article in French | AIM (Africa) | ID: biblio-1433989

ABSTRACT

Introduction : Les maladies opportunistes surviennent chez les personnes vivant avec le VIH (PvVIH) dans les situations de prise en charge tardive. En absence de traitements efficace, la multiplication du virus est inévitable et les personnes concernées sont confrontées à une baisse de leur immunité [1]. C'est dans cette situation que des infections opportunistes se déclarent. Objectif: contribuer à une meilleure connaissance des affections opportunistes liées au VIH Méthode : L'étude s'est déroulée dans le service de Médecine Interne du CHU de Bouaké du 1er janvier 2017 au 31 décembre 2020. C'était une étude rétrospective et transversale qui a concerné les dossiers de patients infectés par le VIH hospitalisés dans ledit service. Résultats : L'analyse a noté 327 cas de dossiers complets sur 3815. La prévalence hospitalière était de 8,5%. L'âge moyen était de 36,2 ans et le sex ratio de 0,83. 65,3% des patients n'ont découvert leur statut sérologique que pendant l'hospitalisation dont les motifs étaient dominés par l'altération de l'état général (36,8%) suivi du coma (19,2%). 84,5% des patients avaient le VIH1. Le taux moyen de CD4 était de 50,5% cellules/mm3 . Les affections opportunistes étaient dominées par la tuberculose (41,8% des cas) et la plus létale était la maladie de Kaposi digestif dans 100% des cas. Conclusion: les patients étaient hospitalisés au stade d'altération de l'état général et de coma d'où la forte létalité. La tuberculose était la principale affection opportuniste. Ces résultats montrent avec beaucoup d'intérêt l'importance de la sensibilisation de la population sur le VIH et la nécessité du dépistage précoce.


Introduction: Opportunistic diseases occur in people living with HIV (PvHIV) in situations of late treatment. In the absence of effective treatments, the multiplication of the virus is inevitable and the people concerned are confronted with a drop in their immune defenses [1, 2]. It is in this situation that opportunistic infections occur Objective: to contribute to a better understanding of opportunistic infections linked to HIV. Method: The study took place in the Internal Medicine department of the Bouake University Hospital from January 1, 2017 to December 31, 2020. It was a retrospective and cross-sectional study which concerned the files of patients infected with HIV hospitalized in the said department. Results: The analysis noted 327 cases of complete records out of 3815. The hospital prevalence of 8.5%. The mean age was 36 years and the sex ratio 0.83. 65.3% of patients only discovered their serological status during hospitalization, the reasons for which were dominated by deterioration in general condition (36%) followed by coma (19.2%). 84.5% of patients had HIV1. The average CD4 count was 50.5% cell/mm3. Opportunistic diseases were dominated by tuberculosis (38% of cases) and the most lethal was digestive Kaposi in 100% of cases. Conclusion: Most of our patients were without social security and did not know their HIV status. These patients were hospitalized at the stage of impaired general condition and coma, hence the high lethality observed. The main opportunistic infections were tuberculosis, cerebral toxoplasmosis and digestive mycoses. These results show with great interest the importance of sensitizing the general population on HIV AIDS and the need for early detection of these opportunistic diseases.


Subject(s)
Sarcoma, Kaposi , Tuberculosis , CD4 Antigens , HIV Infections , AIDS-Related Opportunistic Infections , CD4 Lymphocyte Count
4.
Rev Neurol (Paris) ; 177(6): 670-675, 2021 Jun.
Article in English | MEDLINE | ID: mdl-33066995

ABSTRACT

INTRODUCTION: Cerebral venous thrombosis (CVT) are underdiagnosed in sub-saharan Africa where publications are uncommon. Our study aim was to describe the CVT diagnostic and therapeutic features through a senegalese case series. PATIENTS AND METHOD: A monocentric retrospective and prospective study was conducted at the adult Neurology department of Fann Teaching Hospital in Dakar (Senegal), between January 01, 2013 and April 30, 2020. It had included all CVT cases diagnosed by neurovascular imaging. RESULTS: Seventy CVT cases were collected including 48 women (68.6%). The average age of the patients was 35.2±14 years. The main neurological signs were headache (92.8%) and motor deficit (41.4%), with subacute onset in 67.2% of cases. The superior sagittal sinus (54.3%) and the transverse sinus (38.6%) were the most affected with multiple involvements in 27 patients (38.6%). Thirty patients (42.8%) had indirect parenchymal signs such as venous infarction (15.7%), cerebral edema (11.4%) or intracerebral hemorrhage (12.8%). The etiological factors were mostly infectious (41.4%) with meningoencephalitis (12.8%) and otorhinolaryngological infection (10%). Gyneco-obstetric factors (27%) and Behçet's disease (7%) were the main aseptic factors. In the short-term clinical course, curative anticoagulation (98.6%) had enabled a favourable outcome (mRS 0-1) in half of the patients. CONCLUSION: Our study, the largest series in sub-saharan Africa to this date, confirms that CVT is a young women disease. Infectious etiology is the most frequent at the Fann national teaching hospital (41.4% in Dakar against 6.5% in Germaine Bousser's series) even if the etiological assessment is limited by financial constraints (no coagulopathy/thrombophilia check-up).


Subject(s)
Intracranial Thrombosis , Neurology , Venous Thrombosis , Adult , Africa South of the Sahara , Female , Hospitals, Teaching , Humans , Middle Aged , Pregnancy , Prospective Studies , Retrospective Studies , Senegal , Young Adult
6.
Rev Neurol (Paris) ; 176(5): 366-369, 2020 May.
Article in English | MEDLINE | ID: mdl-32204918

ABSTRACT

Strokes can significantly affect the autonomy and the ability of the patient to feed properly. Malnutrition after strokes increases the length of stay in hospital, increases mortality and aggravates disability. Nutritional support is a therapeutic that can be useful in the management of strokes and during the rehabilitation period. It may help to reduce the occurrence of complications due to the physical dependence associated with this condition. The objective of our study was to evaluate, through a questionnaire, the opinion of prescribing doctors working in the Department of Neurology of The FANN National Teaching Hospital in Dakar. The interest of the question resides in the fact that the Center does not have a dedicated nutritionist for inpatients. This was an opinion poll about their concerns about the nutritional status of patients in the therapeutic projects they propose during the stroke. The type of the chosen opinion poll was elementary, type random. The questionnaire was individual and consisted of five items of single-response and multiple-choice questions. The results of this study reveal that while the nutritional status of patients with limited autonomy in the service was a concern in the intentions of the prescribers, in practice it was not taken into account in therapeutic projects. To date, no structured protocol is available in cases of proven nutritional deterioration in patients. Nutritional management must be integrated into the overall management of Neurology patients, particularly in elderly victims of strokes.


Subject(s)
Nutritional Status , Nutritional Support , Practice Patterns, Physicians'/statistics & numerical data , Stroke/epidemiology , Stroke/therapy , Aged , Aged, 80 and over , Deglutition Disorders/complications , Deglutition Disorders/diagnosis , Deglutition Disorders/epidemiology , Deglutition Disorders/therapy , Female , Health Knowledge, Attitudes, Practice , Hospitalization/statistics & numerical data , Humans , Male , Malnutrition/diagnosis , Malnutrition/epidemiology , Malnutrition/etiology , Malnutrition/therapy , Middle Aged , Nutritional Support/methods , Nutritional Support/psychology , Nutritional Support/statistics & numerical data , Risk Factors , Senegal/epidemiology , Stroke/complications , Stroke/diagnosis , Surveys and Questionnaires
7.
Mali Med ; 35(4): 42-45, 2020.
Article in French | MEDLINE | ID: mdl-37978751

ABSTRACT

Periodontal or gingival recession is the term used to characterize the apical displacement of the marginal gingiva on the surface of the root beyond the enamel junction. THE OBJECTIVE: of this study was to determine the prevalence of periodontal recession in the Dentistry Department of the Bamako Hospital Infirmary. METHOD: This study was carried out in the dentistry department of the Bamako Hospital Infirmary over a 3-month period from January 15 to April 15, 2020. The inclusion criteria concerned patients who came for consultation in the department. A survey sheet comprising socio-demographic and clinical variables was developed for this purpose. RESULTS: The prevalence of periodontal recession was 23.64%. Men were the most represented with 63.9%. Oral hygiene was fair with 42.62%, 36% of periodontal recessions were shallow and narrow. Miller's Class I and Class II recession types were the most represented with 41%. The incisors were the most affected with a rate of 29.64%. At the community level, adequate awareness and education in maintaining oral hygiene should prove successful in the long term.


La récession parodontale ou gingivale est le terme utilisé pour caractériser le déplacement apical de la gencive marginale à la surface de la racine au-delà de la jonction amelocementaire. L'OBJECTIF: de cette étude était de déterminer la prévalence de la récession parodontale dans le service d'Odontologie de l'Infirmerie Hôpital de Bamako. MÉTHODE: Cette étude a été réalisée dans le service d'odontologie de l'Infirmerie Hôpital de Bamako sur une période de 3 mois du 15 janvier au 15 Avril 2020. Les critères d'inclusion concernaient les patients venus en consultation dans le service. Une fiche d'enquête comportant les variables sociodémographiques et les variables cliniques a été élaborée à cet effet. RÉSULTAT: La prévalence de la récession parodontale était de 23,64%. Les hommes étaient les plus représentés avec 63,9%. L'hygiène bucco-dentaire était passable dans 42,62% des cas et 36% des récessions parodontales étaient peu profondes et étroites. Les types de récession de classe I et II de Miller étaient les plus représentés avec 41%. Les incisives étaient les plus touchées avec un taux de 29,64%. Au niveau communautaire une sensibilisation et une éducation adéquate en matière de maintien de l'hygiène buccale s'avère bénéfique à long terme.

8.
Article in French | AIM (Africa) | ID: biblio-1264299

ABSTRACT

L'inclusion des incisives centrales maxillaires pose un problème esthétique et fonctionnel. La prise en charge ortho-chirurgicale est la thérapeutique la plus pratiquée et celle qui donne le meilleur rendu esthétique et fonctionnel. Elle nécessite cependant un bon diagnostic clinique et radiologique afin que la théra-peutique se déroule dans des conditions optimales. La désinclusion ortho-chirurgicale se fait en différentes étapes comme l'illustre le cas clinique présenté ici


Subject(s)
Clinical Decision-Making , General Surgery , Incisor , Orthodontics , Senegal , Tooth, Unerupted
9.
Bull Soc Pathol Exot ; 112(3): 137-146, 2019.
Article in French | MEDLINE | ID: mdl-31825191

ABSTRACT

Neuro-Behçet (NB) African studies are mainly North African, but Sub-Saharan Africa is not to be outdone. Our aim was to describe diagnostic and therapeutic features of NB in a Senegalese series collected in Dakar. This was a descriptive and retrospective study conducted at the Neurology department of Fann Teaching Hospital in Dakar, Senegal. All patients who met the NB's diagnostic criteria were included. Sixteen patients were collected, 14 males and 2 females with an average age of 40 years [18-71]. The main neurological signs were motor deficit (13 cases), headache (10 cases), and language disorders (4 cases). Extra-neurological signs were dermatological (14 cases), ocular (2 cases), and articular (2 cases) with aseptic unilateral gonarthritis. Fever was present in 9 patients. Neurological involvement was mostly isolated parenchymal (8 cases) or mixed (6 cases). The main clinical forms of NB were rhombencephalitis (8 cases) and retrobulbar optic neuritis (4 cases). Seven patients had a cerebral angio-Behçet with cerebral venous thrombosis (3 cases), ischemic stroke (2 cases), and intracerebral hematoma (2 cases). Under prednisone (16 cases) and azathioprine (3 cases), the short-term clinical outcome was mostly favorable (14 cases) with a modified Rankin scale at 2. NB is an under-diagnosed adult male disease in Sub-Saharan Africa and further studies are needed.


Les études africaines sur le neuro-Behçet (NB) sont majoritairement maghrébines, mais l'Afrique noire n'est pas en reste. L'objectif de l'étude était de décrire les particularités diagnostiques et thérapeutiques du NB dans une série sénégalaise colligée à Dakar. Il s'agit d'une étude rétrospective à visée descriptive menée à la clinique de neurologie du centre hospitalier universitaire de Fann de Dakar, au Sénégal. Tous les patients répondant aux critères diagnostiques de NB ont été inclus. Seize patients ont été colligés, 14 hommes et deux femmes avec un âge moyen de 40 ans [18­71]. Les principaux signes neurologiques étaient un déficit moteur (13 cas), des céphalées (10 cas) et un trouble du langage (4 cas). Les signes extraneurologiques étaient dermatologiques (14 cas), oculaires (2 cas) et articulaires (2 cas) à type de gonarthrite unilatérale aseptique. Une fièvre était présente chez neuf patients. L'atteinte neurologique était majoritairement parenchymateuse isolée (8 cas) ou mixte (6 cas). Les principales formes cliniques de NB étaient la rhombencéphalite (8 cas) et la névrite optique rétrobulbaire (4 cas). Sept patients avaient un angio-Behçet cérébral à type de thromboses veineuses cérébrales (3 cas), d'infarctus cérébraux (2 cas) et d'hématomes intracérébraux (2 cas). Sous prednisone (16 cas) et azathioprine (3 cas), l'évolution clinique à court terme était majoritairement favorable (14 cas) avec un score de Rankin modifié de 2 au moment de l'exeat. Le NB est une maladie de l'homme adulte sous-diagnostiquée en Afrique noire. Des études ultérieures multicentriques nationales et sous-régionales sont souhaitables.


Subject(s)
Behcet Syndrome/complications , Behcet Syndrome/diagnosis , Behcet Syndrome/therapy , Intracranial Thrombosis/diagnosis , Intracranial Thrombosis/etiology , Intracranial Thrombosis/therapy , Adolescent , Adult , Africa South of the Sahara/epidemiology , Aged , Behcet Syndrome/epidemiology , Cerebral Hemorrhage/diagnosis , Cerebral Hemorrhage/epidemiology , Cerebral Hemorrhage/etiology , Cerebral Hemorrhage/therapy , Cohort Studies , Female , Hospitals, Teaching , Humans , Intracranial Thrombosis/epidemiology , Male , Middle Aged , Retrospective Studies , Senegal/epidemiology , Young Adult
10.
Bull Soc Pathol Exot ; 109(2): 77-9, 2016 May.
Article in French | MEDLINE | ID: mdl-26936766

ABSTRACT

Nervous localisations of schistosomiasis are rare. We report the case of a 25 year-old Senegalese patient admitted for a progressive myeloradiculitis onset, over a one week period. The diagnosis of Schistosoma haematobium myeloradiculitis was made in front of a positive serum serology for S. haematobium, presence of S. haematobium eggs in urine, hyperproteinorachia, endemicity of S. haematobium in the region where the patient was originating and a past medical history of macroscopic hematuria in a context of river bathing. There was also no arguments for another cause to these neurological manifestations. Our patient was treated with praziquantel, prednisone and physiotherapy. Evolution was marked 6 weeks after the beginning of treatment by a significant improvement of motor deficit, enabling the patient to walk again. There was also a regression of genitosphincter dysfunction. Work-up for patients presenting with paraplegia in tropical countries, should also include search for S. heamatobium infection.


Subject(s)
Neuroschistosomiasis/pathology , Schistosoma haematobium/physiology , Schistosomiasis haematobia/pathology , Adult , Animals , Humans , Male , Neuroschistosomiasis/drug therapy , Neuroschistosomiasis/rehabilitation , Physical Therapy Modalities , Praziquantel/administration & dosage , Prednisone/administration & dosage , Schistosoma haematobium/isolation & purification , Schistosomiasis haematobia/complications , Schistosomiasis haematobia/drug therapy , Schistosomiasis haematobia/rehabilitation , Senegal
11.
Med Sante Trop ; 26(2): 170-4, 2016 May 01.
Article in English | MEDLINE | ID: mdl-26948189

ABSTRACT

Strokes occur increasingly frequently in people aged 55 years or younger and present a problem of management and therefore of prognosis. The objective of this study was to determine the prognostic factors associated with hemorrhagic stroke in this population in Senegal. This retrospective study concerns 53 patients aged 16 to 55 years, hospitalized for hemorrhage stroke in the neurological department of Fann Teaching Hospital during 2010. The patients' mean age was 42.1 years (16 to 55 years) and the sex ratio 1.30 in favor of women. Hypertension was found in 62% of the patients, and 11% had a history of stroke. Hemiplegia was observed in 76%, associated more or less with impairment of consciousness (43%) and language (38%). Intraparenchymal hematomas were principally supratentorial (78%); only 15% were subtentorial (10% cerebellar and 5% in the brainstem). During the acute phase of hemorrhage, glycemic levels were high among one third of the patients. The mortality rate in our series was 43% and was highest among those of impaired consciousness and abnormal glycemic, cholesterol, and creatinemia levels. Neuropsychological sequelae occurred in 47% of all patients, including 83% of the survivors. Hemorrhagic stroke in people aged 55 years or younger is a public health problem. In view of the high mortality rate, effective control requires prevention of its risk factors and increased awareness of the danger of these factors and of the warning signs of stroke.


Subject(s)
Intracranial Hemorrhages/epidemiology , Stroke/epidemiology , Adolescent , Adult , Age Factors , Developing Countries , Female , Humans , Intracranial Hemorrhages/complications , Male , Middle Aged , Prognosis , Retrospective Studies , Senegal/epidemiology , Stroke/etiology , Young Adult
12.
Rev Pneumol Clin ; 72(2): 129-35, 2016 Apr.
Article in French | MEDLINE | ID: mdl-26651930

ABSTRACT

INTRODUCTION: Tuberculosis (TB) remains a real problem of public health in Côte d'Ivoire. The aim of our study is to describe the dynamic of anti-TB fight indicators in anti-TB center (CAT) of Adjamé. METHODOLOGY: We realized a retrospective study, comparing the anti-TB activities of two periods (1999-2001 versus 2010-2012) at the CAT of Adjamé. Over two periods, 24,520 cases of TB were recorded in the registers of TB declaration. RESULTS: Logistic regression results were the following ones. The proportion of the patients of Adjamé municipality increased to detriment of the patients coming from other municipalities. Our study showed an increase of TB contagious forms, a reduction of new cases of TB. The rate of screening of HIV infection increased. We noted a reduction of TB-HIV co-infection prevalence. The proportion of smear positive at the 2nd month decreased. We noted an increase of the rate therapeutic success and a reduction of lost at follow-up. CONCLUSION: Important progresses were realized in the TB fight and TB-HIV co-infection.


Subject(s)
Ambulatory Care/standards , Quality Indicators, Health Care , Tuberculosis/therapy , Adolescent , Adult , Aged , Cote d'Ivoire/epidemiology , Female , Humans , Male , Middle Aged , Prevalence , Quality Indicators, Health Care/statistics & numerical data , Retrospective Studies , Tertiary Care Centers/standards , Tuberculosis/epidemiology , Young Adult
13.
Rev Pneumol Clin ; 71(1): 20-6, 2015 Feb.
Article in French | MEDLINE | ID: mdl-25681315

ABSTRACT

INTRODUCTION: Multidrug-resistant tuberculosis (MDR-TB) is a major obsession for TB control. The main risk factor for MDR-TB remains a history of TB treatment especially bad conduct. The objective of this study is to describe the profile of patients in situations of failure and relapse of tuberculosis. METHODS: We performed a retrospective survey of the analysis of records of patients starting TB retreatment for failure or relapse of tuberculosis. We used 193 cases with results of culture-sensitivity. RESULTS: The proportion of failure is 59/193 (30.6 %) and cases of relapse are 134/193 (69.4 %). The proportion of married life is 23.4 % (11/47) in chess against 41.5 % (51/123) in relapse of TB [P=0.021, OR=0.431 (0.201 to 0.927)]. Patients failing therapy have more chest pain [5.8 % (3/52) versus 0 % (0/126) with P=0.024]. The proportion of MDR-TB was 61.4 (38/59) in case of failure against 41 % (55/134) in case of relapse [P=0.002, OR=2.599 (1.378 to 4.902)]. The evolution is the same whatever the indication of reprocessing. CONCLUSION: The proportion of MDR-TB is very important in case of reprocessing failure and relapse of tuberculosis.


Subject(s)
Antitubercular Agents/therapeutic use , Tuberculosis, Pulmonary , Adolescent , Adult , Aged , Child , Cote d'Ivoire/epidemiology , Disease Progression , Female , Humans , Male , Middle Aged , Recurrence , Retrospective Studies , Treatment Failure , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/epidemiology , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/pathology , Young Adult
14.
Mali Med ; 30(4): 21-25, 2015.
Article in French | MEDLINE | ID: mdl-29927130

ABSTRACT

This work was aimed to describe the epidemiological, clinical, biological and electrical aspects of orthostatic low blood pressure (LBP) within patients with high blood pressure (HBP) in the cardiology department of the Kati University Hospital. This was a prospective cross-sectional study conducted between June 1st, 2012 and May 31st, 2013. It included all the patients with HBP regularly assessed for at least a month, following their treatment and having no other treatments which can induce a orthostatic LBP. RESULTS: With a total of 300 subjects with high blood pressure, 42 subjects presented an orthostatic LBP with or without suggestive clinical demonstrations, among which 16 men and 26 women, with an average age of 55 year. In the HBP population, the orthostatic LBP had a 14% frequency (42/300), the sex ratio was 0.61. Most of the patients were 55 years old or more. The HBP was not controlled in 66.7% of cases. Twelve percent of the patients with orthostatic LBP were diabetics. The number of antihypertensive drug used did not appear to influence the appearance of an orthostatic LBP. Monotherapy was associated with an orthostatic LBP in 47.6% of cases and this monotherapy used the calcic inhibitors in 62% of the cases. Orthostatic low blood pressure is frequent within patient with HBP undergoing treatment. It must be systematically looked for, especially in the uncontrolled HBP, among older subjects, the diabetics, and those with a personal history of neurological disease.


OBJECTIF: Ce travail visait à décrire les aspects épidémiologiques, cliniques, biologiques et électriques de l'hypotension orthostatique chez l'hypertendu dans le service de cardiologie du CHU de Kati. PATIENTS ET MÉTHODES: L'étude était transversale et prospective allant du 1er Juin 2012 au 31 Mai 2013 dans le service de cardiologie du CHU de Kati. Il s'agissait de l'ensemble des patients hypertendus régulièrement suivis depuis un mois et plus, bien observant et n'ayant pas d'autres traitements pouvant favorisés l'hypotension orthostatique. RÉSULTATS: Au total 42 sujets présentant une hypotension orthostatique avec ou sans manifestations cliniques évocatrices ont étés inclus, dont 16 hommes et 26 femmes, en moyenne âgés de 55 ans. Dans la population d'hypertendus, l'hypotension orthostatique avait une fréquence de 14% (42/300), le sex ratio était de 0,61. Les patients âgés de plus de 55 ans étaient plus nombreux. L'hypertension artérielle n'était pas contrôlée dans 66,7%. 11,9% des patients hypotendus orthostatiques étaient diabétiques. Le nombre d'antihypertenseur utilisé ne paraissait pas influencer l'apparition d'une hypotension orthostatique. La monothérapie était associée à une hypotension orthostatique dans 47,6% et cette monothérapie utilisait les inhibiteurs calciques dans 62% des cas. CONCLUSION: L'hypotension orthostatique est fréquente chez les hypertendus traités. Elle doit être recherchée systématiquement, en particulier dans l'HTA non contrôlée, chez les sujets âgés, les diabétiques, et chez ceux ayant un antécédent neurologique.

15.
Mali Med ; 30(1): 7-10, 2015.
Article in French | MEDLINE | ID: mdl-29927150

ABSTRACT

OBJECTIVE: This study aimed to describe epidemiological, clinical, and biological aspects of proteinuria in hypertensive patients in the cardiology department of the Gabriel Touré University Hospital in Bamako. PATIENTS AND METHODS: A cross-sectional descriptive study conducted from January to December 2007 in the cardiology department of the Gabriel Touré University Hospital. RESULTS: A total of 114 subjects were included (60 men and 54 women) with a mean age of 57 years, the sex ratio was 1.11. In the hypertensive population, stage 1 to 2 chronic renal failure was found in 12.9% (114/880). Patients under 60 years of age were more frequently affected with 61.5%. Proteinuria was found in 37 among 114 patients in chronic renal failure (32.5%). Proteinuria frequency in the general hypertensive population was 4.2% (37/880). Microalbuminuria was predominant compared to macro-albuminuria: 25.5% versus 7%. Dyspnea (38.6%) and headache (36.8%) were the main symptoms of hypertension. Renal ultrasound was abnormal in 14.1% with a predominance of stage 0 (76%), stages 1 and 2 each accounted for 7%. CONCLUSION: Proteinuria is a biological anomaly frequently associated with hypertension. His research is required when renal impairment is associated with hypertension. Its discovery in hypertension significantly changes the management strategy of this affection.


OBJECTIF: Ce travail visait à décrire les aspects épidémiologiques, cliniques et biologiques de la protéinurie chez l'hypertendu avec une augmentation de la créatininémie dans le service de cardiologie du CHU Gabriel TOURE de Bamako. PATIENTS ET MÉTHODES: L'étude était transversale et descriptive allant du 1er Janvier au 31 Décembre 2007 dans le service de cardiologie du CHU Gabriel TOURE. RÉSULTATS: Au total 114 sujets ont étés inclus, dont 60 hommes et 54 femmes, en moyenne âgés de 57 ans, le sex ratio était de 1,11. Dans la population d'hypertendus, l'IRC débutante à modérée avait une fréquence de 12,9% (114/880). Les patients âgés de moins de 60 ans étaient plus nombreux avec une fréquence de 61,5%. La protéinurie était retrouvée chez 37/114 patients en insuffisance rénale chronique soit 32,5%. La fréquence de la protéinurie dans la population générale d'hypertendus était de 4,2 % (37/880).L'atteinte rénale marquée par la micro-albuminurie était prédominante par rapport à la macro-albuminurie : 25,5% contre 7%. La dyspnée (38,6%) et les céphalées (36,8%) étaient les principales manifestations de l'HTA. L'échographie rénale était anormale dans 14,1% avec une prédominance du stade 0 (76 %), les stades 1 et 2 représentaient chacun 7%. CONCLUSION: La protéinurie est une anomalie biologique fréquemment associée à l'HTA. Sa recherche s'impose lorsqu'une atteinte rénale est associée à l'HTA. Sa découverte au cours de l'HTA change considérablement la stratégie de prise en charge de cette affection.

16.
Mali méd. (En ligne) ; 30(1): 7-10, 2015.
Article in French | AIM (Africa) | ID: biblio-1265683

ABSTRACT

Objectif. Ce travail visait a decrire les aspects epidemiologiques; cliniques et biologiques de la proteinurie chez l'hypertendu avec une augmentation de la creatininemie dans le service de cardiologie du CHU Gabriel TOURE de Bamako. Patients et methodes. L'etude etait transversale et descriptive allant du 1er Janvier au 31 Decembre 2007 dans le service de cardiologie du CHU Gabriel TOURE. Resultats. Au total 114 sujets ont etes inclus; dont 60 hommes et 54 femmes; en moyenne ages de 57 ans; le sex ratio etait de 1;11. Dans la population d'hypertendus; l'IRC debutante a moderee avait une frequence de 12;9 (114/880). Les patients ages de moins de 60 ans etaient plus nombreux avec une frequence de 61;5. La proteinurie etait retrouvee chez 37/114 patients en insuffisance renale chronique soit 32;5. La frequence de la proteinurie dans la population generale d'hypertendus etait 4;2 (37/880).L'atteinte renale marquee par la micro albuminurie etait predominante par rapport a la macro albuminurie : 25;5 contre 7. La dyspnee (38;6) et les cephalees (36;8) etaient les principales manifestations de l'HTA. L'echographie renale etait anormale dans 14;1 avec une predominance du stade 0 (76); les stades 1 et 2 representaient chacun 7. Conclusion. La proteinurie est une anomalie biologique frequemment associee a l'HTA. Sa recherche s'impose lorsqu'une atteinte renale est associee a l'HTA. Sa decouverte au cours de l'HTA change considerablement la strategie de prise en charge de cette affection


Subject(s)
Cardiology Service, Hospital , Hypertension , Proteinuria , Renal Insufficiency, Chronic
17.
Rev Neurol (Paris) ; 170(10): 608-13, 2014 Oct.
Article in French | MEDLINE | ID: mdl-24953171

ABSTRACT

INTRODUCTION: Epilepsy is a public health problem in Senegal and Africa because of its severity and its social importance. It occurs at any age sparing no sex. It can influence sexual life and reciprocally. Our aims were to study the effects of antiepileptic drugs on the sexual lives of women with epilepsy, the influence of these drugs on pregnancy and breastfeeding. METHODS: We conducted a prospective study from 1st March to 31st August 2011 in the neurological department of the Fann-Dakar teaching hospital Senegal. Only women with epilepsy were included. RESULTS: We collected 120 patients aged 16-64years with a mean age of 30.58years, 45% married, 44.16% were uneducated preponderant. All patients were taking antiepileptic drugs, 89.16% was alone. Fifty-five percent of our patients had epilepsy for at least 6years; 45.83% had generalized epilepsy; 44.17% of partial seizures. In our cohort, 64.16% were under phenobarbital, 69.16% had good adherence. As side effects of drugs, 90% had sexual problems. Seventy-five percent enjoyed an active sex life. A decrease in the number of sex per week for the disease [31/55=56.66%] was noted. In addition, 51.17% were using contraception, including 38.7% of oral kind and 64.86% had noticed an increase in seizure frequency during their pregnancies. Of the 74 women who had contracted a pregnancy, 41.89% had premature infants, 16.21% have made abortions and 61.17% had psychosocial life affected. DISCUSSION AND CONCLUSION: People with epilepsy often experience sexual problems that may be caused by epilepsy, antiepileptic and/or reactions of the partner and the other facing the diagnosis of epilepsy.


Subject(s)
Anticonvulsants/pharmacology , Anticonvulsants/therapeutic use , Epilepsy/drug therapy , Reproductive Health , Sexuality/drug effects , Adolescent , Adult , Female , Humans , Middle Aged , Prospective Studies , Senegal , Young Adult
18.
Mali Med ; 29(4): 34-37, 2014.
Article in French | MEDLINE | ID: mdl-30049113

ABSTRACT

AIM: To specify indications and main anomalies of the 24 hours electrocardiogram in Bamako. METHODOLOGY: The study was retrospective and conducted from 1st January 2008 to 31st July 2013, on patients whose file comprised a readable recording holter. The Holter recordings were analyzed by the software synetec (syneview 2) of ELA medical. Patients data were analyzed by SPSS 18 and redaction made using Word 2010. RESULTS: 90.2% of the recordings were retained. Mean Age of the sample was of 44,02 ± 16,95 years, the sex-ratio H: F 1,18 with 79.3% of patients coming from the services of cardiology. The indications were: palpitations (32.6%), suspicions of disorder of the rate/rhythm (27.2%), loss of consciousness, cerebral vascular accidents ischemic each one 15.2% and seeks of cause of faintness in (9.8%). An anomaly was found for the indications of disorder of the cardiac rhythm, palpitations, the cerebral vascular accidents ischemic, fainting and the losses of consciousness in resp. 80%, 66.6%, 28.5%, 22.2% and 14.2%. CONCLUSION: The 24 hours electrocardiographic recording is an examination of a great value in looking for cardiac rhythm disorders field of the disorders of the cardiac rhythm. Its provision will have to be effective in the university structures and the evolution towards the forms at longer duration quickly undertaken in Mali.


BUT: Préciser les indications et les principales anomalies du Holter électrocardiographique à Bamako. MÉTHODOLOGIE: L'étude était retrospective allant du 1er janvier 2008 au 31 juillet 2013 et portait sur des patients dont le dossier comportait un enregistrement holter bien lisible. Les enregistrements Holter étaient analysés par le logiciel synetec (syneview 2) de la société ELA médical. Les données des patients ont été analysées par SPSS 18 et saisies sur Word 2010. RÉSULTATS: 90,2% des examens holter effectués ont été retenus. L'âge moyen de l'échantillon était de 44,02 ± 16,95 ans, le sex-ratio H:F 1,18 avec 79,3% de patients provenant des services de cardiologie.Les indications étaient: palpitations ( 32,6%), suspicions de trouble du rythme (27,2 %), perte de connaissance, accidents vasculaires cérébraux ischémiques chacun 15,2% et recherche de cause de malaise dans (9,8%). Une anomalie était retrouvée pour les indications de trouble du rythme cardiaque, les palpitations, les accidents vasculaires cérébraux ischémiques, les malaises et les pertes de connaissance dans resp. 80%, 66,6, 28,5%, 22,2% et 14,2%. CONCLUSION: L'enregistrement Holter électrocardiographique de 24 heures est un examen d'une grande valeur dans le domaine des troubles du rythme cardiaque. Sa mise à disposition devra être effective dans les structures universitaires et l'évolution vers les formes à durée plus longue rapidement entreprise au Mali.

19.
Mali Med ; 29(1): 29-33, 2014.
Article in French | MEDLINE | ID: mdl-30049138

ABSTRACT

OBJECTIVE: This work aimed to study the quality of diagnosis and management of high blood pressure (HBP) by the practitioners of the Gabriel TOURÉ and point G teaching hospitals of Bamako. MATERIALS AND METHODS: It was a descriptive and analytical, cross-sectional study during the study period from 1st March 2009 to 28 February 2010. It included all physicians and paramedics of the teaching hospital of the Point G and Gabriel TOURÉ in Bamako. RESULTS: A total of 283 practitioners (physicians and the paramedics) from both teaching hospitals have accepted our questionnaire, including 133 doctors and 185 paramedics. CHU Gabriel TOURÉ accounted for 55.1%, the majority came from the department of cardiology with 18.4%. Doctors accounted for the largest square with 47.0%. The majority of our practitioners (59%) say it takes at least one session during three medical consultations to diagnose the HBP. Only 29,60% define the HBP from 140/90 mm Hg. With a blood pressure goal of 58, 30% and 57.20% of practitioners claimed to retain 140/90 mm Hg, respectively for the diabetic and the renal-insufficient patients. A considerable number of our practitioners (27.9%) still used in pregnant women the triplet diuretic/IEC/diet without salt. The information of patients on some important aspects of the pathology prior to any therapeutic strategy had been conducted in 63.6. CONCLUSION: The high blood pressure must be a major concern for medical and paramedical staff today.


OBJECTIF: Ce travail visait à étudier la qualité du diagnostic et de la prise en charge de l'hypertension artérielle par les praticiens du CHU Gabriel TOURE et de point G de Bamako. MATÉRIELS ET MÉTHODES: Il s'agissait d'une étude transversale descriptive et analytique, pendant la période d'étude du 1er mars 2009 au 28 Février 2010. Elle a concerné l'ensemble des médecins et des paramédicaux des centres hospitalo ­ universitaires du Point G et Gabriel TOURE de Bamako. RÉSULTATS: Au total 283 praticiens (médecins et des paramédicaux) des deux centres hospitalo - universitaires ont accepté notre questionnaire, dont 133 médecins et 185 paramédicaux. Le CHU Gabriel TOURE représentait 55,1%, la majorité provenait du service de cardiologie avec 18,4%. Les médecins ont constitué la plus grande proportion avec 47,0%. La majorité de nos praticiens (59%) affirmaient qu'il faut au moins une séance de prise tensionnelle pendant trois consultations médicales pour diagnostiquer l'HTA. Seulement 29,60% définissent l'HTA à partir de 140/90 mm Hg. Comme objectif tensionnel 58, 30% et 57,20% des praticiens affirmaient retenir 140/90 mm Hg respectivement chez le diabétique et l'insuffisant rénal. Un nombre considérable de nos praticiens (27,9 %) utilisait encore chez la femme enceinte le triplet Diurétique/IEC/Régime sans sel. L'information des patients sur certains aspects importants de la pathologie avant toute stratégie thérapeutique avait été effectuée dans 63,6. CONCLUSION: L'hypertension artérielle doit être une préoccupation majeure pour tout personnel médical et paramédical de nos jours.

20.
Arch Pediatr ; 20(11): 1212-1218, 2013 Nov.
Article in French | MEDLINE | ID: mdl-24090669

ABSTRACT

Congenital hypomagnesemia is a rare disease, with an impact on cognitive and neurological development. We report on three familial cases of congenital hypomagnesemia, two boys and one girl who belong to the same consanguineous family. They all presented neonatal seizures and a psychomotor developmental delay. Cerebral computed tomography showed cerebral atrophy and calcifications in one case and magnetic resonance imaging found predominant cerebellar atrophy in the two other cases. All three patients also had hypocalcemia, hyperphosphoremia, and hypomagnesemia. The parathyroid hormone blood level was low in two cases and normal in the third. One 7-month old patient died. The others received a supplementation of calcium and magnesium, which normalized calcemia, phosphatemia but not magnesemia, which remained low despite high doses. They have both developed cognitive and behavioral impairments.


Subject(s)
Hypocalcemia/diagnosis , Magnesium Deficiency/congenital , Magnesium Deficiency/diagnosis , Renal Tubular Transport, Inborn Errors/diagnosis , Seizures/etiology , Atrophy , Brain/pathology , Calcinosis , Consanguinity , Female , Humans , Hyperphosphatemia/genetics , Hypocalcemia/congenital , Hypocalcemia/genetics , Infant , Infant, Newborn , Magnesium Deficiency/genetics , Male , Parathyroid Hormone/blood , Renal Tubular Transport, Inborn Errors/genetics
SELECTION OF CITATIONS
SEARCH DETAIL
...