ABSTRACT
Anaemia is common in a wide range of malignancies and individual studies have demonstrated it to be an independent prognostic marker for survival in certain cancer types. The study population consisted of 171 patients: 77 anaemic and 94 non-anaemic. Sixty per cent of the study population had adenocarcinoma with 37% having squamous cell carcinoma. Late-stage disease occurred in 80% of individuals. There was no significant difference in survival times between the two groups (p=0.1), and after adjusting for confounding factors including age, sex, stage and physical status (p=0.8). Anaemic individuals with adenocarcinoma suffered a poorer survival probability compared to those with normal haemoglobon level (p=0.02). Anaemia is common at diagnosis in oesophageal cancer and was found to be a significant prognostic indicator of survival in adenocarcinoma, but not squamous cell carcinoma.
Subject(s)
Adenocarcinoma/mortality , Anemia , Carcinoma, Squamous Cell/mortality , Esophageal Neoplasms/mortality , Hemoglobins/metabolism , Adenocarcinoma/blood , Adult , Aged , Aged, 80 and over , Anemia/blood , Anemia/etiology , Carcinoma, Squamous Cell/blood , Disease Progression , Esophageal Neoplasms/blood , Female , Humans , Male , Middle Aged , Neoplasm Staging , PrognosisABSTRACT
Kikuchi's disease is usually a self limiting illness characterised by pyrexia, neutropenia, and cervical lymphadenopathy particularly in young women of Asian descent. This often leads to an initial misdiagnosis of lymphoma. A case of a young Asian woman who presented with pyrexia of unknown origin is described.
Subject(s)
Fever of Unknown Origin/etiology , Lymphatic Diseases/complications , Adult , Biopsy/methods , Diagnosis, Differential , Female , Histiocytic Necrotizing Lymphadenitis/complications , Histiocytic Necrotizing Lymphadenitis/diagnosis , Humans , Lymphatic Diseases/diagnosis , Neck , Neutropenia/etiologyABSTRACT
Strictures, both benign and malignant, of the distal common bile duct (CBD) are reasonably common, and if stented are usually approached endoscopically via the duodenum, or transhepatically via an intrahepatic and then common hepatic duct. We describe a case of endoscopic stenting of a distal CBD stricture over a wire passed percutaneously through the gallbladder, cystic duct and into the duodenum. To our knowledge, this has not been previously described.
