Failure of an Abiomed left ventricular assist device in association with factor VIIa administration.

Factor VIIa might be a useful treatment for coagulopathy and massive hemorrhage following implantation of a mechanical circulatory assist device, but there is a theoretical risk of device thrombosis. To date this complication has not been reported. We describe the first case of clotting of a left ventricular assist device immediately after administration of factor VIIa.