[Soft tissue reconstruction of the finger with free, posterior ramus of the anterior interosseous artery-based septo-cutaneous flap. Anatomy--technique--case examples]. / Weichteilrekonstruktion der Finger mit freien, auf dem Ramus posterior der Arteria interossea anterior basierenden septokutanen Lappen. Anatomie--Technik--Fallbeispiele.

In cases of larger soft-tissue defects of the fingers which cannot be covered with local or regional flaps, pedicled or even free flaps can be used. Pedicled flaps and most free flaps are too bulky and need several trimmings before a cosmetically and functionally satisfactory result is achieved. Free flaps used for soft-tissue reconstruction in digits should be thin and should have a low donor-site morbidity. The free flaps based on the anterior interosseous artery, especially the one based on the dorsal branch, are ideal for soft-tissue reconstruction of single digits. They are very thin and can be harvested in the same operative field. Donor-site morbidity is usually low. The clinical usefullness of this flap is shown in the reconstruction of three consecutive cases of severely damaged fingers.

[Familial cancer. Initial results of an inquiry into its occurrence in Basel]. / Familiäre Tumorkrankheiten. Erste Ergebnisse einer Erhebung über ihr Vorkommen in Basel.

The initial results of a systematic study conducted in Basel on the existence of relatives with cancer in the families of more than 600 tumour patients indicate that neoplasm of all organs have forms in whose etiology genetic predisposition is an important factor. This is illustrated by the examples of mammary carcinoma, colorectal carcinoma, gastric carcinoma and lymphoproliferative diseases. Research into genetic predisposition to cancer is of practical value in order to protect persons at risk from the serious consequences of malignant tumors, and also of scientific interest because the characterisation of certain tumours can provide a fundamental insight into the pathogenesis of these diseases.