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Dermatol Clin ; 37(1): 73-82, 2019 Jan.
Article in English | MEDLINE | ID: mdl-30466690

ABSTRACT

Skin cancer is reaching epidemic levels in the United States. Recent advances in the understanding of the pathophysiology of melanoma have allowed improved risk stratification in the revised American Joint Committee on Cancer (AJCC) criteria, new tests to capture patients at higher risk than their stage may indicate, and new treatments to offer hope and cures to patients with advanced disease.


Subject(s)
Antineoplastic Agents, Immunological/therapeutic use , Gene Expression Profiling , Melanoma/drug therapy , Melanoma/genetics , Neoplasm Recurrence, Local/genetics , Protein Kinase Inhibitors/therapeutic use , Skin Neoplasms/drug therapy , Skin Neoplasms/genetics , CTLA-4 Antigen/antagonists & inhibitors , Humans , Lymph Node Excision , Melanoma/etiology , Melanoma/secondary , Molecular Targeted Therapy , Neoplasm Staging , Predictive Value of Tests , Prognosis , Programmed Cell Death 1 Receptor/antagonists & inhibitors , Sentinel Lymph Node Biopsy , Skin Neoplasms/etiology , Skin Neoplasms/pathology
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