Neural correlates of tonal loudness, intensity discrimination, and duration discrimination.

A long-standing quest in audition concerns understanding relations between behavioral measures and neural representations of changes in sound intensity. Here, we examined relations between aspects of intensity perception and central neural responses within the inferior colliculus of unanesthetized rabbits (by averaging the population's spike count/level functions). We found parallels between the population's neural output and: (1) how loudness grows with intensity; (2) how loudness grows with duration; (3) how discrimination of intensity improves with increasing sound level; (4) findings that intensity discrimination does not depend on duration; and (5) findings that duration discrimination is a constant fraction of base duration.

Intelligibility and detectability of speech measured diotically and dichotically in groups of listeners with, at most, "slight" hearing loss.

The purpose of this investigation was to determine if a group of listeners having thresholds at 4 kHz exceeding 7.5 dB HL, and no more than "slight" hearing loss, would exhibit degradations in performance when "target" stimuli were masked tokens of speech. Intelligibility thresholds and detection thresholds were measured separately for speech masked by flat-spectrum noise or speech-shaped noise. Both NoSo and NoSπ configurations were employed. Consistent with findings of earlier investigations, when maskers and speech tokens were broadband, NoSo and NoSπ detection thresholds were substantially lower than intelligibility thresholds. More importantly, for the small cohorts tested, mean thresholds obtained from the ≤7.5 dB and >7.5 dB groups were equivalent. When maskers and speech targets were high-pass filtered at 500 Hz and above, the mean intelligibility thresholds obtained from the >7.5 dB group were about 4 dB higher than those obtained from the ≤7.5 dB group, independent of masker type and interaural configuration of the stimuli. In real-world listening situations, such deficits may manifest themselves as substantially reduced speech intelligibility and, perhaps, increased "listening effort" for listeners whose thresholds at 4 kHz exceed 7.5 dB HL and who have no more than "slight" hearing loss.

A crew of listeners with no more than "slight" hearing loss who exhibit binaural deficits also exhibit reduced amounts of binaural interference.

Listeners having, at most, "slight" hearing loss, specifically those having absolute thresholds at 4 kHz exceeding 7.5 dB HL, have been shown to exhibit deficits in binaural detection that appear to stem from increased levels of stimulus-dependent, additive internal noise [Bernstein and Trahiotis (2016). J. Acoust. Soc. Am. 140, 3540-3548; Bernstein and Trahiotis (2018). J. Acoust. Soc. Am. 144, 292-307]. This study assessed whether such listeners exhibit greater susceptibility to "binaural interference." NoSo and NoSπ tone-in-noise detection thresholds were measured for stimuli centered at 4 kHz in the absence of any interfering stimuli and in the presence of simultaneously gated diotic or interaurally uncorrelated noise centered at 500 Hz. Results indicated that listeners exhibiting elevated NoSπ thresholds (typical of those in ">7.5 dB groups"), actually exhibit less binaural interference than do those exhibiting lower NoSπ thresholds typical of those in "≤7.5 dB HL" groups. That outcome cannot be explained by a "ceiling effect" stemming from interferer-induced loss of the ability to utilize binaural cues to detect the signal. The relatively smaller amounts of binaural interference exhibited by listeners with relatively elevated NoSπ thresholds notwithstanding, it is argued that the interference they do exhibit may place them at a distinct disadvantage in everyday listening environments.

Binaural detection as a joint function of masker bandwidth, masker interaural correlation, and interaural time delay: Empirical data and modeling.

Empirical data are reported demonstrating how binaural detection is affected by joint variation of masker bandwidth, masker interaural correlation, and interaural time delay (ITD) of both masker and tonal signal. Most of the data were obtained with stimuli centered at 500 Hz; supplemental measures were obtained with stimuli centered at 4 kHz. The results indicate that as the interaural correlation of the masker (ρ) is decreased there is (1) an overall increase in threshold signal-to-noise ratio (S/N) and (2) a progressively smaller effect on threshold S/N as ITD is increased. All of the data were accounted for quite accurately using the same quantitative, interaural cross-correlation-based model that was recently shown to account for binaural detection and discrimination data obtained in previous experiments. Importantly, the new data were predicted and explained using values of model parameters that were identical or very close to those found to predict accurately the earlier data. The success of the enterprise attests to the robustness of the approach and the generality of the model's ability to make accurate predictions of binaural performance over a wide range of historically important stimulus conditions.

A crew of listeners with no more than "slight" hearing loss who exhibit binaural deficits also exhibit higher levels of stimulus-independent internal noise.

Listeners having, at most, "slight" hearing loss may exhibit deficits in binaural detection which appear to stem from increased levels of stimulus-dependent, additive internal noise [Bernstein and Trahiotis, J. Acoust. Soc. Am. 140, 3540-3548 (2016); J. Acoust. Soc. Am. 144, 292-307 (2018)]. This study reports that a small crew of such listeners also exhibits increased levels of low-level, stimulus-independent, additive internal noise. Detection thresholds were measured in: (1) the NoSπ configuration as a function of masker level; (2) the NρSπ configuration as a function of masker interaural correlation (ρ); (3) "the quiet" for So and Sπ tonal signals. Those measures were combined suitably to yield estimates of stimulus-independent, additive internal noise, separately, at center frequencies of 250, 500, and 4000 Hz. Derived levels of internal noise were found to be elevated, by about 5 dB at 250 and 500 Hz, and by about 9 dB at 4 kHz, for the group of listeners having no more than slight hearing loss and who exhibited deficits in binaural detection. The new findings, taken together with earlier investigations by the authors (which included data obtained from dozens of listeners), provide evidence that such listeners have greater levels of both stimulus-dependent and stimulus-independent, additive internal noise.

No more than "slight" hearing loss and degradations in binaural processing.

Listeners having, at most, "slight" hearing loss may exhibit substantial deficits in binaural detection [Bernstein and Trahiotis. (2016). J. Acoust. Soc. Am. 140, 3540-3548; (2018). J. Acoust. Soc. Am. 144, 292-307]. This study assessed whether such listeners also exhibit deficits discriminating interaural temporal disparities (ITDs) or interaural intensitive disparities (IIDs) and whether any deficits observed in those discrimination tasks would be accounted for by the interaural cross-correlation based model that successfully accounts for binaural detection. Thresholds were measured for detection of tones masked by noise in the NoSπ configuration and discrimination of ITD or IID. Gaussian noises (100 Hz-wide), served as maskers in the detection task and as reference and target stimuli in the discrimination tasks. Stimuli were centered at 500 Hz or 4 kHz. The latter were transpositions of stimuli centered at 125 Hz. Results demonstrate that listeners having, at most, slight hearing loss and who exhibit deficits in binaural detection, also exhibit deficits in ITD- and IID-discrimination. Coupled with appropriate decision variables, the cross-correlation-based model that accounts for elevated binaural detection thresholds among such listeners also accounted for their elevated ITD- and IID-thresholds. The deficits in all three tasks appear to stem from increased levels of stimulus-dependent, additive internal noise.

The fMRI Data of Thompson et al. (2006) Do Not Constrain How the Human Midbrain Represents Interaural Time Delay.

This commentary provides an alternate interpretation of the fMRI data that were presented in a communication to the journal Nature Neuroscience (Thompson et al., Nat. Neurosci. 9: 1096-1098, 2006 ). The authors argued that their observations demonstrated that traditional models of binaural hearing which incorporate "internal delays," such as the coincidence-counting mechanism proposed by Jeffress and quantified by Colburn, are invalid, and that a new model for human interaural time delay processing must be developed. We argue that the fMRI data presented do not strongly favor either the refutation or the retention of the traditional models, although they may be useful in constraining the physiological sites of various processing stages. The conclusions of Thompson et al. are based on the locations of maximal activity in the midbrain in response to selected binaural signals. These locations are inconsistent with well-known perceptual attributes of the stimuli under consideration, as is noted by the authors, which suggests that further processing is involved in forming the percept of subjective lateral position.

Effects of interaural delay, center frequency, and no more than "slight" hearing loss on precision of binaural processing: Empirical data and quantitative modeling.

This study assessed how precision of binaural processing is affected by center frequency (CF), interaural temporal disparity (ITD), and listeners' hearing status. Tonal signals and 100-Hz-wide Gaussian noise maskers were employed at CFs ranging between 250 and 8000 Hz, in octave steps. In addition, for CFs of 2000, 4000, and 8000 Hz, transposed maskers and signals were employed. All listeners had no greater than "slight" hearing losses (i.e., no thresholds greater than 25 dB HL). Across all CFs and ITDs tested, binaural detection thresholds were elevated for listeners whose absolute thresholds at 4 kHz exceeded 7.5 dB HL. That outcome is consistent with results from Bernstein and Trahiotis [(2016). J. Acoust. Soc. Am. 140, 3540-3548]. Quantitative predictions of binaural detection thresholds derived via a comprehensive interaural correlation-based model of binaural processing were highly accurate across the entire set of data. The modeling results suggest that elevated thresholds from listeners having small hearing losses stem from elevated levels of stimulus-dependent, additive internal noise. They do not appear to stem from increased levels of noise within the central binaural comparator or from reduced sensitivity to changes in interaural correlation produced by the addition of the signal to the masker.

Stimulus coherence influences sound-field localization and fusion/segregation of leading and lagging sounds.

The ability to localize sound sources in reverberant environments is dependent upon first-arriving information, an outcome commonly termed "the precedence effect." For example, in laboratory experiments, the combination of a leading (direct) sound followed by a lagging (reflected) sound is localized in the direction of the leading sound. This study was designed to measure the degree to which stimulus compactness/diffuseness (i.e., coherence as represented by interaural cross correlation) of leading and lagging sounds influences performance. The compactness/diffuseness of leading or lagging sounds was varied by either presenting a sound from a single loudspeaker or by presenting mutually uncorrelated versions of similar sounds from nine adjacent loudspeakers. In separate experiments, the listener's task was to point to the perceived location of leading and lagging 10-ms long low-pass filtered white noises or 2-s long tokens of speech. The leading and lagging stimuli were presented either from speakers located directly in front of the listeners or from speakers located ±45° to the right or left. The results indicate that leading compact (coherent) sounds influence perceived location more so than do leading diffuse (incoherent) sounds. This was true independent of whether the sounds were Gaussian noises or tokens of speech.

An interaural-correlation-based approach that accounts for a wide variety of binaural detection data.

Interaural cross-correlation-based models of binaural processing have accounted successfully for a wide variety of binaural phenomena, including binaural detection, binaural discrimination, and measures of extents of laterality based on interaural temporal disparities, interaural intensitive disparities, and their combination. This report focuses on quantitative accounts of data obtained from binaural detection experiments published over five decades. Particular emphasis is placed on stimulus contexts for which commonly used correlation-based approaches fail to provide adequate explanations of the data. One such context concerns binaural detection of signals masked by certain noises that are narrow-band and/or interaurally partially correlated. It is shown that a cross-correlation-based model that includes stages of peripheral auditory processing can, when coupled with an appropriate decision variable, account well for a wide variety of classic and recently published binaural detection data including those that have, heretofore, proven to be problematic.

Behavioral manifestations of audiometrically-defined "slight" or "hidden" hearing loss revealed by measures of binaural detection.

This study assessed whether audiometrically-defined "slight" or "hidden" hearing losses might be associated with degradations in binaural processing as measured in binaural detection experiments employing interaurally delayed signals and maskers. Thirty-one listeners participated, all having no greater than slight hearing losses (i.e., no thresholds greater than 25 dB HL). Across the 31 listeners and consistent with the findings of Bernstein and Trahiotis [(2015). J. Acoust. Soc. Am. 138, EL474-EL479] binaural detection thresholds at 500 Hz and 4 kHz increased with increasing magnitude of interaural delay, suggesting a loss of precision of coding with magnitude of interaural delay. Binaural detection thresholds were consistently found to be elevated for listeners whose absolute thresholds at 4 kHz exceeded 7.5 dB HL. No such elevations were observed in conditions having no binaural cues available to aid detection (i.e., "monaural" conditions). Partitioning and analyses of the data revealed that those elevated thresholds (1) were more attributable to hearing level than to age and (2) result from increased levels of internal noise. The data suggest that listeners whose high-frequency monaural hearing status would be classified audiometrically as being normal or "slight loss" may exhibit substantial and perceptually meaningful losses of binaural processing.

The import of within-listener variability to understanding the precedence effect.

The purpose of this study was to gather behavioral data concerning the precedence effect as manifested by the localization-dominance of the leading elements of compound stimuli. This investigation was motivated by recent findings of Shackleton and Palmer [(2006). J. Assoc. Res. Otolaryngol. 7, 425-442], who measured the electro-physiological responses of single units in the inferior colliculus of the guinea pig. The neural data from Shackleton and Palmer indicated that processing of binaural cues like those relevant to understanding localization dominance is greatly affected by internal, neural noise. In order to evaluate the generality of their physiological results to human perception, the present study measured localization dominance so that behavioral responses within and across sets of samples (i.e., tokens) of frozen noises could be compared. Conceptually consistent with Shackleton and Palmer's neural data, the variability of perceived intracranial lateral positions produced by repeated presentations of the same tokens of noise was greater than the variability of intracranial lateral positions measured across different tokens of noise. This was true for each of the four individual listeners and for each of the 72 stimulus conditions studied. Thus, measured either neuro-physiologically (Shackleton and Palmer, 2006) or behaviorally (this study), the import of within-listener variability appears to be a general, intrinsic aspect of binaural information processing.

Converging measures of binaural detection yield estimates of precision of coding of interaural temporal disparities.

This presentation reports binaural detection data obtained using a special set of three stimulus configurations. The configurations are shown to yield "converging" measures that allow one to describe how precision of coding of interaural temporal disparities (ITDs) changes as a function of both reference ITD and the center frequency of the stimuli.

Accounting for binaural detection as a function of masker interaural correlation: effects of center frequency and bandwidth.

Binaural detection was measured as a function of the center frequency, bandwidth, and interaural correlation of masking noise. Thresholds were obtained for 500-Hz or 125-Hz Sπ tonal signals and for the latter stimuli (noise or signal-plus-noise) transposed to 4 kHz. A primary goal was assessment of the generality of van der Heijden and Trahiotis' [J. Acoust. Soc. Am. 101, 1019-1022 (1997)] hypothesis that thresholds could be accounted for by the "additive" masking effects of the underlying No and Nπ components of a masker having an interaural correlation of ρ. Results indicated that (1) the overall patterning of the data depended neither upon center frequency nor whether information was conveyed via the waveform or by its envelope; (2) thresholds for transposed stimuli improved relative to their low-frequency counterparts as bandwidth of the masker was increased; (3) the additivity approach accounted well for the data across stimulus conditions but consistently overestimated MLDs, especially for narrowband maskers; (4) a quantitative approach explicitly taking into account the distributions of time-varying ITD-based lateral positions produced by masker-alone and signal-plus-masker waveforms proved more successful, albeit while employing a larger set of assumptions, parameters, and computational complexity.

Sensitivity to envelope-based interaural delays at high frequencies: center frequency affects the envelope rate-limitation.

Sensitivity to ongoing interaural temporal disparities (ITDs) was measured using bandpass-filtered pulse trains centered at 4600, 6500, or 9200 Hz. Save for minor differences in the exact center frequencies, those target stimuli were those employed by Majdak and Laback [J. Acoust. Soc. Am. 125, 3903-3913 (2009)]. At each center frequency, threshold ITD was measured for pulse repetition rates ranging from 64 to 609 Hz. The results and quantitative predictions by a cross-correlation-based model indicated that (1) at most pulse repetition rates, threshold ITD increased with center frequency, (2) the cutoff frequency of the putative envelope low-pass filter that determines sensitivity to ITD at high envelope rates appears to be inversely related to center frequency, and (3) both outcomes were accounted for by assuming that, independent of the center frequency, the listeners' decision variable was a constant criterion change in interaural correlation of the stimuli as processed internally. The finding of an inverse relation between center frequency and the envelope rate limitation, while consistent with much prior literature, runs counter to the conclusion reached by Majdak and Laback.

The effect of overall level on sensitivity to interaural differences of time and level at high frequencies.

For high-frequency complex stimuli, detection thresholds for envelope-based interaural time differences (ITDs) decrease with overall level. Substantial heterogeneity is, however, evident among the findings concerning the rate at which thresholds decline with level. This study investigated factors affecting the influence of overall level on threshold ITDs. Thresholds were measured as a function of overall level for 4-kHz-centered "targets" in three experiments focusing, respectively, on stimulus-type (sinusoidally amplitude-modulated or "transposed" tones), modulation frequency, and details concerning low-pass noise used to mask low-frequency distortion products. Results indicated that (1) log-ITD thresholds decreased linearly with overall level; (2) slopes relating log-ITD thresholds to level did not depend significantly on stimulus type; (3) lower modulation frequencies produced greater dependencies of thresholds on overall level than did higher modulation frequencies; (4) the effect of overall level on threshold-ITDs was independent of the interaural configuration and levels of the low-pass noise maskers tested; (5) synchronously gating the low-pass noise and target produced a greater dependency of thresholds on the overall level of the target than did continuous or temporally "fringed" presentation of the noise. A fourth experiment showed that threshold interaural level differences were somewhat less affected by changes in overall level than were threshold ITDs.

When and how envelope "rate-limitations" affect processing of interaural temporal disparities conveyed by high-frequency stimuli.

The purpose of this chapter is to bring together historical and current findings that reveal the presence, influence, and operation of a type of envelope "rate-limitation." The rate-limitation has been revealed in both monaural and binaural experiments. Specifically, there appears to be a low-pass envelope-filtering process that (1) functionally attenuates fluctuations of the envelope above about 150 Hz and (2) is not attributable to peripheral band-pass filtering. We show a variety of empirical outcomes and theoretical analyses that converge to demonstrate and to describe how this type of filtering constrains the processing of interaural temporal disparities (ITDs) conveyed by the envelopes of high-frequency stimuli in experiments concerning binaural detection. Included are recent behavioral and neurophysiological findings regarding how such filtering may vary with the center frequency of the stimulus.

Lateralization produced by interaural temporal and intensitive disparities of high-frequency, raised-sine stimuli: data and modeling.

An acoustic pointing task was used to measure extents of laterality produced by combinations of ongoing envelope-based interaural temporal disparities (ITDs) and interaural intensitive disparities (IIDs) of 4-kHz-centered raised-sine stimuli [Bernstein and Trahiotis, J. Acoust. Soc. Am. 125, 3234-3242 (2009),] while varying, parametrically, their peakedness, depth of modulation, and frequency of modulation. The study was designed to assess whether IIDs act as "weights" within the putative "binaural display" at high spectral frequencies (where the envelopes convey ITD-information) as appears to be the case at low spectral frequencies (where the waveforms, i.e., fine-structure and envelopes, convey ITD-information). The data indicate that envelope-based IIDs do principally act as weights and that they appear to exert their influence on lateral position independently of the influence of ITDs. Quantitative analyses revealed that an augmented form of the cross-correlation-based "position-variable" model of Stern and Shear [J. Acoust. Soc. Am. 100, 2278-2288 (1996)] accounted for 94% of the variance in the data. This success notwithstanding, for a small subset of the data, predictions could be improved by assuming that the listeners utilized information within auditory filters having center frequencies above 4 kHz.