ABSTRACT
Background: Female sexual function has been shown to improve with overactive bladder (OAB) treatment. Aim: The objective of this study was to evaluate the effects of anticholinergics (ACHs) or a beta-agonist (BAG) on female sexual function. Methods: This was a prospective multicenter cohort study. Sexually active women with OAB completed the Overactive Bladder questionnaire (OAB-q) and Female Sexual Function Index (FSFI) prior to and after 12 weeks of therapy. Sample sizes of 63 per group were calculated to detect a clinically relevant difference in the FSFI. Outcomes: The primary outcome was FSFI change from baseline at 12 weeks. Results: A total of 157 patients were recruited, and 91 completed follow-up (58/108, ACH; 31/49, BAG). There were within-group FSFI differences from pre- to posttreatment: a worsening of arousal in the ACH group (P = .046) and an improvement in overall FSFI (P = .04) and pain (P = .04) in the BAG group. After treatment, postmenopausal women in the BAG group had significantly better overall FSFI (P = .01), desire (P = .003), arousal (P = .009), and orgasm (P = .01). Clinical Implications: While further research is necessary, this study provides information about the comparative effects of OAB treatments on female sexual function, which may ultimately lead to better patient selection and outcomes. Strengths and Limitations: While there was no difference between the subjects who completed the study and those who did not, the study remained underpowered after the loss to follow-up. The multicenter cohort design allows for generalizability of results. Conclusion: Although this study was underpowered, an improvement in overall sexual function was seen with BAGs, while ACHs were associated with worsening aspects of sexual function.
ABSTRACT
OBJECTIVES: The objective was to assess female pelvic medicine and reconstructive surgery (FPMRS) fellowship applicants' perspectives on the effectiveness of the virtual interview format for creating their rank lists. METHODS: This was an anonymous internet-based survey study of applicants to the FPMRS fellowships in the United States, conducted from July 21, 2020, to August 5, 2020. A 34-item questionnaire queried applicants on satisfaction with interviews, comfort with creating a rank list and time, and financial cost of interviews. Applicants were invited to complete the survey via standardized emails distributed via the REDCap secure database. RESULTS: Forty-two (56.7%) of 74 applicants completed the survey. The majority of respondents were somewhat satisfied or very satisfied (92.9%) with the virtual interview process and felt comfortable ranking the programs (83.3%). A total of 9.8% of respondents found virtual interviews somewhat or much better than in-person interviews with regards to being informative and helpful, whereas 61% found them to be about the same. A majority (75.6%) found virtual interviews somewhat or much less stressful compared with in-person interviews. The majority (97.5%) spent less than $2,000 during the application process compared with more than $4,000 (87.8%) that they had anticipated spending if the interviews were in person. CONCLUSIONS: Our data revealed that FPMRS applicants overall had a positive experience with the virtual interview platform and felt comfortable creating a rank list of programs based on those interviews.
