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1.
Sci Data ; 11(1): 321, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38548727

ABSTRACT

Flexible bronchoscopy has revolutionized respiratory disease diagnosis. It offers direct visualization and detection of airway abnormalities, including lung cancer lesions. Accurate identification of airway lesions during flexible bronchoscopy plays an important role in the lung cancer diagnosis. The application of artificial intelligence (AI) aims to support physicians in recognizing anatomical landmarks and lung cancer lesions within bronchoscopic imagery. This work described the development of BM-BronchoLC, a rich bronchoscopy dataset encompassing 106 lung cancer and 102 non-lung cancer patients. The dataset incorporates detailed localization and categorical annotations for both anatomical landmarks and lesions, meticulously conducted by senior doctors at Bach Mai Hospital, Vietnam. To assess the dataset's quality, we evaluate two prevalent AI backbone models, namely UNet++ and ESFPNet, on the image segmentation and classification tasks with single-task and multi-task learning paradigms. We present BM-BronchoLC as a reference dataset in developing AI models to assist diagnostic accuracy for anatomical landmarks and lung cancer lesions in bronchoscopy data.


Subject(s)
Bronchoscopy , Lung Neoplasms , Humans , Artificial Intelligence , Lung Neoplasms/diagnostic imaging , Thorax/diagnostic imaging , Anatomic Landmarks/diagnostic imaging
2.
Med Image Anal ; 78: 102422, 2022 05.
Article in English | MEDLINE | ID: mdl-35339951

ABSTRACT

Multiphase CT scanning of the liver is performed for several clinical applications; however, radiation exposure from CT scanning poses a nontrivial cancer risk to the patients. The radiation dose may be reduced by determining the scan range of the subsequent scans by the location of the target of interest in the first scan phase. The purpose of this study is to present and assess an automatic method for determining the scan range for multiphase CT scans. Our strategy is to first apply a CNN-based method for detecting the liver in 2D slices, and to use a liver range search algorithm for detecting the liver range in the scout volume. The target liver scan range for subsequent scans can be obtained by adding safety margins achieved from Gaussian liver motion models to the scan range determined from the scout. Experiments were performed on 657 multiphase CT volumes obtained from multiple hospitals. The experiment shows that the proposed liver detection method can detect the liver in 223 out of a total of 224 3D volumes on average within one second, with mean intersection of union, wall distance and centroid distance of 85.5%, 5.7 mm and 9.7 mm, respectively. In addition, the performance of the proposed liver detection method is comparable to the best of the state-of-the-art 3D liver detectors in the liver detection accuracy while it requires less processing time. Furthermore, we apply the liver scan range generation method on the liver CT images acquired from radiofrequency ablation and Y-90 transarterial radioembolization (selective internal radiation therapy) interventions of 46 patients from two hospitals. The result shows that the automatic scan range generation can significantly reduce the effective radiation dose by an average of 14.5% (2.56 mSv) compared to manual performance by the radiographer from Y-90 transarterial radioembolization, while no statistically significant difference in performance was found with the CT images from intra RFA intervention (p = 0.81). Finally, three radiologists assess both the original and the range-reduced images for evaluating the effect of the range reduction method on their clinical decisions. We conclude that the automatic liver scan range generation method is able to reduce excess radiation compared to the manual performance with a high accuracy and without penalizing the clinical decision.


Subject(s)
Image Processing, Computer-Assisted , Yttrium Radioisotopes , Humans , Image Processing, Computer-Assisted/methods , Liver/diagnostic imaging , Tomography, X-Ray Computed/methods
3.
IEEE Trans Syst Man Cybern B Cybern ; 35(5): 1079-91, 2005 Oct.
Article in English | MEDLINE | ID: mdl-16240781

ABSTRACT

There are many learning algorithms available in the field of pattern classification and people are still discovering new algorithms that they hope will work better. Any new learning algorithm, beside its theoretical foundation, needs to be justified in many aspects including accuracy and efficiency when applied to real life problems. In this paper, we report the empirical comparison of a recent algorithm RM, its new extensions and three classical classifiers in different aspects including classification accuracy, computational time and storage requirement. The comparison is performed in a standardized way and we believe that this would give a good insight into the algorithm RM and its extension. The experiments also show that nominal attributes do have an impact on the performance of those compared learning algorithms.


Subject(s)
Algorithms , Artificial Intelligence , Cluster Analysis , Information Storage and Retrieval/methods , Pattern Recognition, Automated/methods , Software Validation , Software
4.
IEEE Trans Pattern Anal Mach Intell ; 26(6): 740-55, 2004 Jun.
Article in English | MEDLINE | ID: mdl-18579935

ABSTRACT

A novel method using a reduced multivariate polynomial model has been developed for biometric decision fusion where simplicity and ease of use could be a concern. However, much to our surprise, the reduced model was found to have good classification accuracy for several commonly used data sets from the Web. In this paper, we extend the single output model to a multiple outputs model to handle multiple class problems. The method is particularly suitable for problems with small number of features and large number of examples. Basic component of this polynomial model boils down to construction of new pattern features which are sums of the original features and combination of these new and original features using power and product terms. A linear regularized least-squares predictor is then built using these constructed features. The number of constructed feature terms varies linearly with the order of the polynomial, instead of having a power law in the case of full multivariate polynomials. The method is simple as it amounts to only a few lines of Matlab code. We perform extensive experiments on this reduced model using 42 data sets. Our results compared remarkably well with best reported results of several commonly used algorithms from the literature. Both the classification accuracy and efficiency aspects are reported for this reduced model.


Subject(s)
Algorithms , Artificial Intelligence , Information Storage and Retrieval/methods , Multivariate Analysis , Pattern Recognition, Automated/methods , Benchmarking , Decision Support Techniques , Models, Statistical
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