ABSTRACT
A case of recurrent lentigo maligna in a 45-year-old woman is presented. The disease relapsed several times following the surgical excision of the lesion. An alternative treatment with imiquimod 5% cream was then used. After 4 years of follow-upfrom the last surgery, this treatment achieved total clearance of the lesion. The problems of lentigo maligna diagnosis and treatment are discussed.
Subject(s)
Hutchinson's Melanotic Freckle , Skin Neoplasms , Female , Humans , Middle Aged , Imiquimod , Hutchinson's Melanotic Freckle/drug therapy , Hutchinson's Melanotic Freckle/surgery , Follow-Up Studies , Skin Neoplasms/diagnosis , Skin Neoplasms/drug therapy , Skin Neoplasms/surgery , Aminoquinolines/therapeutic useSubject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Carcinoma, Basal Cell/drug therapy , Ear Neoplasms/drug therapy , Immune Checkpoint Inhibitors/therapeutic use , Skin Neoplasms/drug therapy , Aged , Carcinoma, Basal Cell/pathology , Ear Auricle/pathology , Ear Neoplasms/pathology , Humans , Male , Skin/pathology , Skin Neoplasms/pathologyABSTRACT
The scrotum is a rare site for metastases and represents less than 1% of the body's total surface area. Clinically, metastatic deposits in the scrotum can present in a variety of ways. They may appear as solitary cutaneous nodules, papules, plaques, or generalized induration or edema. Indeed, scrotum metastasis may be mistaken for other skin lesions since several dermatologic conditions can present with inflammation or dermatitis of the scrotum. Properly diagnosing cutaneous metastasis requires histopathological examination since the clinical appearances are, as described, highly variable and non-specific. We present a 63-year-old man with painless nodules on the scrotal skin. Excisional biopsy of the nodules revealed a metastasis from rectal squamous cell carcinoma. The incidence of this kind of tumors is estimated around 0.1-0.25â¯per 1000â¯colorectal neoplasms.
Subject(s)
Carcinoma, Squamous Cell/secondary , Genital Neoplasms, Male/secondary , Rectal Neoplasms/pathology , Scrotum/pathology , Skin Neoplasms/secondary , Humans , Male , Middle AgedSubject(s)
Melanoma , Nevus, Pigmented , Skin Neoplasms , Diagnosis, Differential , Early Diagnosis , Humans , Melanoma/diagnosis , Skin Neoplasms/diagnosisABSTRACT
Cutaneous leiomyosarcoma is a rare malignant mesenchymal tumor of smooth muscle origin of unknown etiology. Leiomyosarcomas located on the skin include superficial leiomyosarcomas and metastatic leiomyosarcomas. Superficial leiomyosarcomas represent 7-10% of all cases of leiomyosarcoma and are subdivided into cutaneous and subcutaneous lesions based on skin location. We report a case of an 81-year-old woman who presented a slow growing tender single nodule on the left thigh and describe its clinical and dermoscopic features.
