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1.
Prog Biophys Mol Biol ; 115(2-3): 349-58, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25091538

ABSTRACT

Cardiovascular Magnetic Resonance (CMR) imaging is an essential technique for measuring regional myocardial function. However, it is a time-consuming and cognitively demanding task to interpret, identify and compare various motion characteristics based on watching CMR imagery. In this work, we focus on the problems of visualising imagery resulting from 2D myocardial tagging in CMR. In particular we provide an overview of the current state of the art of relevant visualization techniques, and a discussion on why the problem is difficult from a perceptual perspective. Finally, we introduce a proof-of-concept multilayered visualization user interface for visualizing CMR data using multiple derived attributes encoded into multivariate glyphs. An initial evaluation of the system by clinicians suggested a great potential for this visualisation technology to become a clinical practice in the future.


Subject(s)
Heart/anatomy & histology , Heart/physiology , Image Interpretation, Computer-Assisted/methods , Imaging, Three-Dimensional/methods , Magnetic Resonance Imaging, Cine/methods , Myocardial Contraction/physiology , Animals , Humans , Reproducibility of Results , Sensitivity and Specificity , Signal Processing, Computer-Assisted , Spatio-Temporal Analysis , Subtraction Technique , User-Computer Interface
2.
Science ; 308(5723): 817-21, 2005 May 06.
Article in English | MEDLINE | ID: mdl-15879209

ABSTRACT

Here we describe the requirements of an e-Infrastructure to enable faster, better, and different scientific research capabilities. We use two application exemplars taken from the United Kingdom's e-Science Programme to illustrate these requirements and make the case for a service-oriented infrastructure. We provide a brief overview of the UK "plug-and-play composable services" vision and the role of semantics in such an e-Infrastructure.


Subject(s)
Computational Biology , Computer Communication Networks , Computing Methodologies , Internet , Research , Software , Chemical Phenomena , Chemistry , Combinatorial Chemistry Techniques , Databases as Topic , Graves Disease/genetics , Williams Syndrome/genetics
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