ABSTRACT
Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs. The condition may manifest through purplish lesions, flat or raised with an irregular shape, gastrointestinal bleeding due to lesions located in the digestive system, and dyspnea and hemoptysis associated with pulmonary lesions. In the early 1980s, the appearance of several cases of Kaposi's sarcoma in homosexual men was the first alarm about a newly identified epidemic, acquired immunodeficiency syndrome. In 1994, it was finally demonstrated that the presence of a herpes virus associated with Kaposi's sarcoma called HHV-8 or Kaposi's sarcoma herpes virus and its genetic sequence was rapidly deciphered. The prevalence of this virus is very high (about 50%) in some African populations, but stands between 2% and 8% for the entire world population. Kaposi's sarcoma only develops when the immune system is depressed, as in acquired immunodeficiency syndrome, which appears to be associated with a specific variant of the Kaposi's sarcoma herpes virus. There are no treatment guidelines for Kaposi's sarcoma established in Brazil, and thus the Brazilian Society of Clinical Oncology and the Brazilian Society of Infectious Diseases developed the treatment consensus presented here.
Subject(s)
Female , Humans , Male , Sarcoma, Kaposi , Brazil , Neoplasm Staging , Prognosis , Risk Factors , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/epidemiology , Sarcoma, Kaposi/therapy , Societies, MedicalABSTRACT
Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs. The condition may manifest through purplish lesions, flat or raised with an irregular shape, gastrointestinal bleeding due to lesions located in the digestive system, and dyspnea and hemoptysis associated with pulmonary lesions. In the early 1980s, the appearance of several cases of Kaposi's sarcoma in homosexual men was the first alarm about a newly identified epidemic, acquired immunodeficiency syndrome. In 1994, it was finally demonstrated that the presence of a herpes virus associated with Kaposi's sarcoma called HHV-8 or Kaposi's sarcoma herpes virus and its genetic sequence was rapidly deciphered. The prevalence of this virus is very high (about 50%) in some African populations, but stands between 2% and 8% for the entire world population. Kaposi's sarcoma only develops when the immune system is depressed, as in acquired immunodeficiency syndrome, which appears to be associated with a specific variant of the Kaposi's sarcoma herpes virus. There are no treatment guidelines for Kaposi's sarcoma established in Brazil, and thus the Brazilian Society of Clinical Oncology and the Brazilian Society of Infectious Diseases developed the treatment consensus presented here.
Subject(s)
Sarcoma, Kaposi , Brazil , Female , Humans , Male , Neoplasm Staging , Prognosis , Risk Factors , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/epidemiology , Sarcoma, Kaposi/therapy , Societies, MedicalABSTRACT
A Sociedade Brasileira de Infectologia foi fundada em 1980, e a Sociedade de Infectologia do Estado do Rio de Janeiro (SIERJ) em 1981. O Projeto Memória SIERJ foi concebido para resgatar e mostrar suas origens. Mostrar onde efervesceram as primeiras ideias, os movimentos iniciais para concretização deste ideal. Mostrar quem foram os médicos que acreditaram nesta proposta, que tiveram a visão de que seriam necessárias uma nova organização e ações independentes. Sem negar o grandioso valor do que se herdou, da organização dos profissionais, do conhecimento das doenças infecciosas e parasitárias, e da luta pelo combate a estas doenças em nosso país. (AU)
