Infarto cerebral migrañoso / Migranial cerebral infartion

Se presenta un caso de migraña complicada. Una joven de 19 años presentó en el curso de una crisis migrañosa severa un infarto cortical derecho, corroborado por la TAC. A propósito de esta paciente, se revisa la literatura y se llama la atención sobre los peligros que pudiese revestir para un jaquecoso subir a la altura

[Disappearance of tardive dyskinesia in a manic attack]. / Disparition de dyskinésies tardives au cours d'un accès maniaque.

A 66 year-old man suffered of a manic-depressive illness. Tardive dyskinesia appeared after a treatment with chlorpromazine. Abnormal movements were present at normal and depressive states, but disappeared during manic phases. A few similar cases have been reported. The authors suggest that a modification in the sensibility of monoaminergic receptors could explain the disappearance of dyskinetic movements during mania.

[Human peripheral neurolymphomatosis]. / La neurolymphomatose périphérique humaine.

Two further cases of human neurolymphomatosis are reported, and clinical, histopathologic and nosologic features of the affection reviewed with respect to findings in these 2 patients and in 7 other reported cases. Clinical manifestations are those of a flaccid ascending paralysis, associated in most cases with an asymmetrical abolition of tendon reflexes, violent muscular pains and sphincter disturbances, frequently preceded by a regressive cranial nerve palsy. Pathology shows infiltration of the peripheral nervous system (nerves, roots, and spinal ganglia) by lymphoid cells, sometimes associated with central nervous system (cord and brain) infiltrates in severe advanced cases. Involved nerves are increased in size. The disease could be a viral polyradiculoneuritis due to the virus of Marek's disease. Arguments in favor of this hypothesis include: the onset of the affection in subjects working in poultry farms under poor hygienic condition; the fact that clinical and histologic findings are similar to those in Marek's disease and the failure, after careful examination, to detect any malignant blood disorder or lymphoma in one of the cases studied.

Cien años de neurología / A century of neurology

Este trabajo acerca de la historia de la Neurología ha sido deliberadamente circunscrito por el autor a los últimos 100 años, a partir de la década de 1860-1970, por varias importantes razones que conciernen tanto a la Neurología como a un trasfondo social. Se escudriña la formación y desarrollo de los grandes centros, La Salpetriere y Queen Square con la contribución de muchos ilustres neurólogos, pero además la visión retrospectiva abarca los aspectos sociales, políticos y científicos de esa época. Esta publicación es parte de un extenso proyecto que incorporará la historia neurológica de otros lugares del mundo en el mismo período de tiempo

[Human peripheral neurolymphomatosis (reticuloendothelial polyradiculoneuritis)]. / Neurolymphomatose périphérique humaine (polyradiculonévrite réticuloendothéliosique)

This is the clinico-pathological report of a case of reticulo-endotheliosis of the nervous system in a 53-year-old white female. She had a history of transient facial palsy followed 6 months later by progressive weakness, paresthesiae and severe pain in both lower limbs. Clinical examination revealed signs of sensory and motor polyradiculoneuritis with involvement of the oculomotor, facial and trigeminal cranial nerves. She died 10 months after the onset because of bronchopneumonia. Pathological findings in the nervous system were limited to the cranial and spinal roots and ganglia. Histopathological examination showed intense infiltration by lymphocytes, histiocytes, plasmocytes and macrophages and a large amount of reticulin. The left oculomotor nerve, both Gasserian ganglia, the right trigeminal nerve and the lumbosacral nerves and ganglia were particularly involved. The previous literature on human peripheral neurolymphomatosis is reviewed and its differential diagnosis from Marek's disease, sarcomas, leukaemic polyradiculoneuritis, sarcoidosis and Hodgkin's disease of the nervous system is discussed. The importance of recognizing this variety of polyradiculoneuritis, and methods of treating it are emphasized.