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3.
Acta Physiol Pol ; 26(4): 419-28, 1975.
Article in English | MEDLINE | ID: mdl-1199750

ABSTRACT

The aim of this work was to examine the effect of a hypertonic solution (Krebs solution + 290 mM urea) on K+ and Na+ transport. The experiments were carried out on the guinea-pig taenia coli preparations using the method of Na-24 and K-24 loading and washout. The efflux curves were analysed by means of the digital computer technique. The following parameters were determined: efflux rate constant k2, influx rate constant k1, intracellular ion concentration C1 ion flux M and permeability P. Any significant difference between PNa/PK ratio in hypertonic urea and isotonic Krebs solutions was found.


Subject(s)
Cell Membrane Permeability/drug effects , Potassium/metabolism , Sodium/metabolism , Urea/pharmacology , Animals , Biological Transport, Active , Colon/metabolism , Guinea Pigs , Hypertonic Solutions , Muscle, Smooth/metabolism
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