ABSTRACT
The coronavirus disease 2019 (COVID-19) has caused over six million deaths worldwide since its emergence in Wuhan China, factors associated with COVID-19 mortality, such as comorbidities, age, and observed symptomatology still remain a major subject of study. In the present work, a total of 16,345 SARS-CoV-2 positive cases from Durango Mexico diagnosed from May 2020 to December 2021 were analyzed to establish an association of COVID-19 mortality with clinical and demographic variables in a case-control study. Selected variables include patient age, smoking status, sex, presence of comorbidities such as hypertension, diabetes and obesity, as well as patient symptomatology such as fever, dyspnea, abdominal pain and diarrhea. Results indicate that among analyzed data, the median age was 43 years; 54% were female, with a mortality rate of 5.66%. Multivariate regression analysis indicated that the comorbidities associated with the highest risk factor were advanced age (>60) with an odds ratio of 4.127 (IC 95%, 3.37-5.05), hypertension with 1.961 (IC 95%, 1.57-2.45), diabetes with 1.753 (IC 95%, 1.39-2.20) and obesity with 1.413 (IC 95%, 1.11-1.78) respectively. On the other hand, the symptom associated with the highest risk factor was dyspnea with an odds ratio of 18.369 (IC 95%, 14.42-23.39). Our data suggests an association between hypertension and old age with COVID-19 mortality. Other findings include the prevalence of dyspnea, polypnea and cyanosis as a major predictor for COVID-19 mortality, as well as lower mortality risks among health workers.
Subject(s)
COVID-19 , Diabetes Mellitus , Hypertension , Humans , Female , Adult , Male , COVID-19/epidemiology , COVID-19/complications , SARS-CoV-2 , Case-Control Studies , Mexico/epidemiology , Risk Factors , Comorbidity , Obesity/epidemiology , Obesity/complications , Diabetes Mellitus/epidemiology , Hypertension/epidemiology , Hypertension/complications , Dyspnea/epidemiologyABSTRACT
El fracaso en el tratamiento de conductos puede conducir a la pérdida del órgano dental, distintos factores han sido reportados como causantes del fracaso en la terapia endodóntica, dentro de estos factores los conductos omitidos tienen un influencia mayor debido a que permiten una colonización y multiplicación de las bacterias dentro del conducto radicular. Variaciones anatómicas anormales pueden aumentar las posibilidades de fracaso debido a la imposibilidad de diagnosticar de manera correcta, es en estos casos que la tomografía computarizada de haz cónico ha demostrado ser de gran ayuda para interpretarlas.
O fracasso no tratamento de canais radiculares pode levar à perda do órgão dental. Vários fatores têm sido relatados como causas de fracasso na terapia endodôntica. Dentre esses fatores, os canais omitidos têm uma influência maior, pois permitem a colonização e multiplicação de bactérias dentro do canal radicular. Variações anatômicas anormais podem aumentar as chances de fracasso devido à dificuldade de diagnóstico preciso. Em tais casos, a tomografia computadorizada de feixe cônico demonstrou ser de grande auxílio para a interpretação.
The failure in root canal treatment can lead to the loss of the dental organ. Various factors have been reported as causes of failure in endodontic therapy. Among these factors, omitted canals have a greater influence, as they allow colonization and multiplication of bacteria within the root canal. Abnormal anatomical variations can increase the chances of failure due to the inability to diagnose accurately. In these cases, cone-beam computed tomography has proven to be of great assistance in their interpretation.
