ABSTRACT
Se estudió un grupo de 38 pacientes asmáticos para correlacionar evolución clínica con resultados de IgE sérica, RAST y pruebas cutáneas. Los resultados revelan que casi 70 por ciento de los pacientes estudiados tuvieron positividad importante en pruebas cutáneas y/o RAST lo cual confirma que la mayoría de los asmáticos tiene un componente alérgico en su causa. La determinación de IgE sérica total demostró no ser un examen definitivo para confirmar el origen alérgico. Sólo 25 por ciento de los pacientes con asma de evolución más grave tuvieron pruebas cutánes o RAST fuertemente positivos
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Adolescent , Asthma/diagnosis , Asthma/immunology , Immunoglobulin E , Immunoglobulin E/immunology , Antigen-Antibody Reactions/immunology , Skin Tests/instrumentationABSTRACT
We studied a group of 38 asthmatic patients to correlate the clinical evolution with results of IgE in serum, RAST and skin tests. Results reveal that almost 70% of the studied patients present important positivity in skin tests or RAST which confirms that the majority of asthmatics have an allergic component in their etiology. The determination of IgE in serum showed not to be a definitive exam to confirm allergic etiology. Only 25% of asthmatic patients with severe evolution presented skin tests or RAST strongly positive.
Subject(s)
Asthma/immunology , Immunoglobulin E/blood , Adolescent , Allergens/immunology , Asthma/etiology , Child , Child, Preschool , Female , Humans , Hypersensitivity, Immediate/complications , Hypersensitivity, Immediate/diagnosis , Infant , Male , Prospective Studies , Radioallergosorbent Test , Skin TestsABSTRACT
OBJECTIVE: To determine the prevalence of gestational diabetes (GD) in an outpatient clinic in northeastern Mexico. PATIENTS: 732 consecutive pregnant women referred for prenatal care during a two-year period. INTERVENTION AND OUTCOME MEASURE: A 100 g glucose tolerance test was performed in the patients with sampling at 1, 2 and 3 hours postchallenge. The patients were classified according to the criteria of the American Diabetes Association as normal, abnormal, and a third category of those showing a single abnormal value in the tolerance test. RESULTS: Six percent of the women (44/732) had GD and 1.4% (10/732) had one abnormal value. A comparison group was made with a subset of 44 of the 678 women who showed a normal tolerance test. No group differences were seen in parity, and age, nor in body weight gain or changes in body mass index, the latter measured in the initial and final weeks of pregnancy. Significant differences versus the normal women were seen in the GD group for cesarean births (43% vs 30%) and in macrosomy (25% vs 7%). The group with one abnormal test showed high values in cesareans (50%) and macrosomy (10%) but did not reach significant difference with the other groups. CONCLUSIONS: GD was higher in our study than in the only paper on GD prevalence reported in Mexico (3.9%). The higher incidence of cesareans and macrosomy in GD makes it necessary to consider therapeutic interventions in these cases.
