ABSTRACT
This article is divided into two main sections, one discussing suicide and substance use, and the other describing substance use and various forms of violent behavior toward others, including sexual assault and domestic violence. In each section, issues regarding prevalence of harm to self and others in substance users, clinical assessment and treatment, etiologic factors, definitional problems, and research needs are discussed. Substance use appears to be associated strongly with both violence toward self and violence toward others, but the exact nature of these relationships is somewhat unclear.
Subject(s)
Dangerous Behavior , Substance-Related Disorders/psychology , Suicide Prevention , Violence/prevention & control , Adult , Female , Humans , Male , Risk Assessment , Suicide/psychology , Violence/psychologyABSTRACT
Gonadoblastoma occurs almost entirely in patients with pure mixed gonadal dysgenesis or in male pseudohermaphrodites. A report of a patient with monolateral gonadoblastoma who sought consultation for primary amenorrhea is presented. Telarche and adrenarche occurred spontaneously at age 12. No signs of clitoromegaly or hirsutism were present. Endoscopic examination and biopsy specimens revealed absence of uterus, monolateral gonadoblastoma and controlateral teratoma in normally developed gonads. Serum gonadotrophins, estrogens and progesterone levels showed a biphasic secretion pattern. 46, XX karyotype was found on peripheral blood cells, skin fibroblasts and ovarian tissue.
