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Preventive treatment with oral sirolimus and aspirin in a newborn with severe Sturge-Weber syndrome.
Pediatr Dermatol
; 36(4): 524-527, 2019 Jul.
Article
in English
| MEDLINE
| ID: mdl-31134637
ABSTRACT
Sturge-Weber syndrome (SWS) is characterized by facial capillary malformation, leptomeningeal capillary malformations, and choroidal and episcleral vascular malformations. These malformations produce neurologic and ophthalmological symptoms including seizures and glaucoma. A premature male newborn without prenatal diagnosis presented with severe bilateral SWS and was started on systemic sirolimus and aspirin. The patient has remained seizure-free for 23 months and demonstrated an excellent response to pulsed dye laser treatment.