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1.
Am J Clin Nutr ; 63(5): 678-86, 1996 May.
Article in English | MEDLINE | ID: mdl-8615349

ABSTRACT

The purpose of this study was to compare the ability of various body-composition assessment techniques to detect changes in soft tissue in older, weight-stable women (50-70 y of age) completing a 1-y randomized, controlled trial of progressive resistance training. The intervention group (n = 20) performed high-intensity strength-training 2 d/wk with five different exercises; the control group (n = 19) was untreated. Hydrostatic weighing, 24-h urinary creatinine, computed tomography of thigh sections, total body potassium, and tritium dilution techniques were used to measure increases in total fat-free mass (FFM) and the muscle and water components of FFM. A decrease in fat mass (by hydrostatic weighing) was seen in the strength-trained women compared with the control subjects (P - 0.01-0.0001). Anthropometry, bioelectric impedance, dual-energy X-ray absorptiometry, and total body nitrogen and carbon did not measure any significant change in soft tissue. The choice of a body-composition technique is important when designing a study expected to affect soft tissue, because not all techniques available are precise enough to detect small changes.


Subject(s)
Body Composition/physiology , Exercise/physiology , Physical Education and Training , Absorptiometry, Photon , Aged , Anthropometry , Body Mass Index , Body Weight , Creatinine/urine , Electric Impedance , Female , Humans , Middle Aged , Neutron Activation Analysis , Radioisotope Dilution Technique , Thigh/diagnostic imaging , Tomography, X-Ray Computed , Tritium
2.
Int J Sport Nutr ; 5(1): 37-44, 1995 Mar.
Article in English | MEDLINE | ID: mdl-7749424

ABSTRACT

In this study a double-blind design was used to determine the effect of caffeine on time to exhaustion and on associated metabolic and circulatory measures. Eight male subjects ingested either caffeine (5 mg/kg body weight) or a placebo 1 hr prior to exercise at 85-90% of maximum workload. Subjects were encouraged to complete three 30-min intermittent cycling periods at 70 rpm with 5 min rest between each. The exercise was terminated when the subject failed to complete three 30-min periods or failed to maintain 70 rpm for at least 15 s consecutively. Serum free fatty acids, glycerol, blood glucose, lactate, perceived exertion, heart rate, and O2 cost were measured. The time to exhaustion was significantly longer during the caffeine trial than during the placebo trial. Serum free fatty acid levels were significantly different between trials. The decline in blood glucose levels was significantly less during the caffeine trial than during the placebo trial. There were no significant differences between trials for the other measures. It was concluded that caffeine increases time to exhaustion when trained subjects cycled intermittently at high levels of intensity.


Subject(s)
Caffeine/pharmacology , Exercise , Physical Exertion/drug effects , Adult , Analysis of Variance , Blood Glucose/metabolism , Double-Blind Method , Exercise Test , Fatty Acids, Nonesterified/blood , Glycerol/blood , Heart Rate/drug effects , Humans , Lactates/blood , Male , Oxygen Consumption/drug effects
3.
JAMA ; 272(24): 1909-14, 1994 Dec 28.
Article in English | MEDLINE | ID: mdl-7990242

ABSTRACT

OBJECTIVE: To determine how multiple risk factors for osteoporotic fractures could be modified by high-intensity strength training exercises in postmenopausal women. DESIGN: Randomized controlled trial of 1-year duration. SETTING: Exercise laboratory at Tufts University, Boston, Mass. POPULATION: Forty postmenopausal white women, 50 to 70 years of age, participated in the study; 39 women completed the study. The subjects were sedentary and estrogen-deplete. INTERVENTIONS: High-intensity strength training exercises 2 days per week using five different exercises (n = 20) vs untreated controls (n = 19). MAIN OUTCOME MEASURES: Dual energy x-ray absorptiometry for bone status, one repetition maximum for muscle strength, 24-hour urinary creatinine for muscle mass, and backward tandem walk for dynamic balance. RESULTS: Femoral neck bone mineral density and lumbar spine bone mineral density increased by 0.005 +/- 0.039 g/cm2 (0.9% +/- 4.5%) (mean +/- SD) and 0.009 +/- 0.033 g/cm2 (1.0% +/- 3.6%), respectively, in the strength-trained women and decreased by -0.022 +/- 0.035 g/cm2 (-2.5% +/- 3.8%) and -0.019 +/- 0.035 g/cm2 (-1.8% +/- 3.5%), respectively, in the controls (P = .02 and .04). Total body bone mineral content was preserved in the strength-trained women (+2.0 +/- 68 g; 0.0% +/- 3.0%) and tended to decrease in the controls (-33+77 g; -1.2% +/- 3.4%, P = .12). Muscle mass, muscle strength, and dynamic balance increased in the strength-trained women and decreased in the controls (P = .03 to < .001). CONCLUSIONS: High-intensity strength training exercises are an effective and feasible means to preserve bone density while improving muscle mass, strength, and balance in postmenopausal women.


Subject(s)
Exercise Therapy , Fractures, Bone/etiology , Fractures, Bone/prevention & control , Osteoporosis, Postmenopausal/complications , Osteoporosis, Postmenopausal/therapy , Aged , Analysis of Variance , Bone Density , Creatinine/urine , Female , Hormones/blood , Humans , Middle Aged , Muscles/physiology , Nutritional Physiological Phenomena , Postural Balance , Risk Factors
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