1.
Nebr Med J
; 72(8): 277-9, 1987 Aug.
Article
in English
| MEDLINE
| ID: mdl-3658030
2.
J Antimicrob Chemother
; 19(5): 617-22, 1987 May.
Article
in English
| MEDLINE
| ID: mdl-3112096
ABSTRACT
Various clinical isolates of mycobacteria were tested for susceptibility to ciprofloxacin by a standard macrobroth dilution test and the radiometric BACTEC method. Agreement between the two test systems was species dependent: Mycobacterium tuberculosis (80%), M. kansasii with M. scrofulaceum (30%), M. avium-intracellulare (20%), and 0% for the rapidly growing mycobacteria. Most mycobacterial strains other than M. tuberculosis were susceptible to the breakpoint ciprofloxacin concentration of 2 mg/l as determined by BACTEC MICs, whereas none were susceptible by macrobroth testing. Seven of nine M. tuberculosis isolates were susceptible by either method. Ciprofloxacin merits further study as a potential antimycobacterial agent.