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1.
J Gastrointest Cancer ; 54(4): 1158-1180, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37155130

ABSTRACT

PURPOSE: Radiomics is a promising method for advancing imaging assessment in rectal cancer. This review aims to describe the emerging role of radiomics in the imaging assessment of rectal cancer, including various applications of radiomics based on CT, MRI, or PET/CT. METHODS: We conducted a literature review to highlight the progress of radiomic research to date and the challenges that need to be addressed before radiomics can be implemented clinically. RESULTS: The results suggest that radiomics has the potential to provide valuable information for clinical decision-making in rectal cancer. However, there are still challenges in terms of standardization of imaging protocols, feature extraction, and validation of radiomic models. Despite these challenges, radiomics holds great promise for personalized medicine in rectal cancer, with the potential to improve diagnosis, prognosis, and treatment planning. Further research is needed to validate the clinical utility of radiomics and to establish its role in routine clinical practice. CONCLUSION: Overall, radiomics has emerged as a powerful tool for improving the imaging assessment of rectal cancer, and its potential benefits should not be underestimated.


Subject(s)
Positron Emission Tomography Computed Tomography , Rectal Neoplasms , Humans , Radiomics , Rectal Neoplasms/diagnostic imaging , Rectal Neoplasms/therapy , Prognosis , Magnetic Resonance Imaging/methods
2.
Artif Organs ; 35(5): 459-64, 2011 May.
Article in English | MEDLINE | ID: mdl-21595712

ABSTRACT

This article investigates the dosimetry of a radioactive stent and radioactive liquid balloon placed into the heart vasculature to prevent restenosis after atherosclerosis treatment. The research aims to know the dosages to establish a suitable activity which achieves restenosis control and thereafter minimize radiation effects in the cardiac muscle. In order to accomplish the dosimetric analysis, a heart voxel model was assembled based on tomographic images. The computational model consists of a three-dimensional matrix taken from 60 tomographic images representing the major heart tissues. A radioactive ¹5³Sm liquid balloon is simulated as well as a ³²P radioactive stent, inserted in an arbitrary heart artery. After simulation processing, the absorbed dose rate was evaluated in the heart musculature. The models are presented in two- and three-dimensional previews and the dosage profiles are shown by isodose curves superimposed onto the heart model.


Subject(s)
Angioplasty/instrumentation , Brachytherapy/instrumentation , Computer Simulation , Coronary Artery Disease/therapy , Coronary Restenosis/prevention & control , Models, Cardiovascular , Radiation Dosage , Stents , Angioplasty/adverse effects , Brachytherapy/adverse effects , Coronary Angiography/methods , Coronary Artery Disease/diagnostic imaging , Coronary Restenosis/diagnostic imaging , Coronary Restenosis/etiology , Humans , Imaging, Three-Dimensional , Phosphorus Radioisotopes , Prosthesis Design , Radiation Injuries/etiology , Radiation Injuries/prevention & control , Radiographic Image Interpretation, Computer-Assisted , Radioisotopes , Radiotherapy, Computer-Assisted , Samarium , Tomography, X-Ray Computed
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