1.
Indian J Med Res
; 92: 417-9, 1990 Dec.
Article
in English
| MEDLINE
| ID: mdl-2079356
ABSTRACT
3,4-Dihydroxyphenyl ethylene glycol (DOPEG), a metabolite of noradrenaline (NA), was estimated in CSF of 30 patients of depression diagnosed by the criteria of American Psychiatric Association in DSM-III; and compared with levels in 10 non-depressed individuals who served as controls. Mean DOPEG levels in CSF in the patient group (801.37 +/- 28.09 micrograms/l) were significantly higher (P less than 0.01) than those in the control group (724.3 +/- 34.62 micrograms/l). Formation of excessive amount of this particular metabolite suggests an excessive intraneuronal deamination of NA, partially accounting for the overall decline in the availability of NA in the noradrenergic neurons in patients of depression.
Subject(s)
Depression/metabolism , Methoxyhydroxyphenylglycol/analogs & derivatives , Depression/cerebrospinal fluid , Female , Humans , India , Male , Methoxyhydroxyphenylglycol/cerebrospinal fluid , Norepinephrine/metabolism
2.
Indian J Med Res
; 86 Suppl: 11-9, 1987.
Article
in English
| MEDLINE
| ID: mdl-3440583
3.
J Assoc Physicians India
; 34(11): 781-3, 1986 Nov.
Article
in English
| MEDLINE
| ID: mdl-3549682
Subject(s)
Captopril/therapeutic use , Heart Failure/drug therapy , Adult , Aged , Cardiac Output/drug effects , Female , Humans , Male , Middle Aged , Myocardial Contraction/drug effects
4.
J Assoc Physicians India
; 33(2): 141-3, 1985 Feb.
Article
in English
| MEDLINE
| ID: mdl-3997753
5.
Indian Heart J
; 33(1): 27-30, 1981.
Article
in English
| MEDLINE
| ID: mdl-7251003
6.
J Assoc Physicians India
; 26(9): 805-9, 1978 Sep.
Article
in English
| MEDLINE
| ID: mdl-370078