ABSTRACT
This study was conducted among 32 pesticide applicators occupationally exposed to pesticides to determine whether paternal exposure is associated with an increased risk of spontaneous abortion. The ratio of abortion was compared between applicators and a group of 51 food retailers (control population). The ratio of abortions/pregnancies for applicators was 0.27 and for retailers 0.07. OR for spontaneous abortion adjusted for age of wife and smoking of parents is 3.8 times greater than for the control population in the multiple logistic regression model and 7.6 times with interaction effects model.
Subject(s)
Abortion, Spontaneous/epidemiology , Agriculture , Occupational Exposure , Paternal Exposure , Pesticides , Abortion, Spontaneous/etiology , Adult , Agrochemicals , Educational Status , Female , Humans , Logistic Models , Male , Pregnancy , SmokingABSTRACT
Fertility among workers exposed to metal fumes and solvents in the Italian mint (stampers, founders, and other technical workers) was compared to the reproductive experience of the administrative staff. Data on the reproductive history and time to pregnancy were collected by interview. For workers with children, data on the time to pregnancy (TTP) for the first pregnancy was assessed in relation to occupational risk factors. The groups with the highest prevalence of pregnancy delay beyond 6 months were stampers (21%) and those exposed to solvents (21.5%). Logistic regression did not show a significant association of these job exposures with pregnancy delay, but the power of the study to show an important difference was low. The data are not inconsistent with the hypothesis that male exposure to solvents and metal fumes is associated with an increase in the TTP.
Subject(s)
Air Pollutants, Occupational/adverse effects , Fertility/drug effects , Infertility, Male/etiology , Metals/adverse effects , Occupational Diseases/etiology , Paternal Exposure/adverse effects , Adult , Birth Rate , Female , Humans , Italy , Logistic Models , Male , Metallurgy , Middle Aged , Pregnancy , Pregnancy Outcome , Solvents/adverse effects , Time FactorsABSTRACT
An existing database on pesticides, running in the DOS/Windows environment, is operative at the National Institute of Health and has yielded useful informations for several published researches. The database is currently being restructured for the purpose of making it available on the Web. An HTML interface, allowing to formulate queries on the database from the Web is presently under development, and it will be made available, once the problems related to confidentiality of certain parts of the database are solved. The database in its present form is presented and necessary changes foreseen in the Web edition are discussed.
