ABSTRACT
Examinations of children in the Moscow region in 1972 revealed low values of the herd immunity to poliomyolitis. This was suggested to be due to improper organization of vaccination of children. The regional health authorities took special measures for better organization of vaccination. The examinations two years later, in 1974, showed nearly 90% of children between the ages of 1 and 6 years to have antibody to all three types of poliomyelitis virus. The geometric mean antibody titre increased. In children of 10--14 years the heard immunity values did not differ significantly from those found in 1972. It is concluded that proper vaccination gives sufficiently intensive immunity nearly in 90% of children. It was found that in children vaccinated 10--12 times the herd immunity persists without significant changes for 3 years after the last vaccine feeding; at 4 years, however, some values of the herd immunity, particularly to poliomyelitis virus type III, were significantly lower than the original values. It is suggested that it is likely to be expedient to revaccinate 4-grade schoolchildren and to reduce the total number of vaccine feedings during the first 4 years of life.
Subject(s)
Immunity, Active , Poliomyelitis/immunology , Poliovirus Vaccine, Oral/administration & dosage , Adolescent , Age Factors , Child , Child, Preschool , Evaluation Studies as Topic , Follow-Up Studies , Humans , Immunization Schedule , Infant , Moscow , Time FactorsABSTRACT
Results of studying group acute intestinal diseases of obscure (from the point of view of isolation of commonly known pathogenic bacteria of enteric family) etiology coursing by the type of food poisoning, in which conditioned pathogenic enterobacteria (Enterobacter cloacae, Klebsiella) demonstrated that the occurrence of these diseases was connected with ingestion of the same food product infected with the mentioned bacteria due to disturbance of the sanitary-epidemic regimen and rules of food storage. Carrier stage of conditioned pathogenic bacteria identical to those isolated from the patients was noted in contacts by the factor of infection transmission. Accumulation of factual material is necessary to solve the role played by conditioned pathogenic enterobacteria in such diseases.
Subject(s)
Enterobacter/isolation & purification , Enterobacteriaceae/isolation & purification , Foodborne Diseases/microbiology , Klebsiella/isolation & purification , Acute Disease , Disease Outbreaks , Food Microbiology , Foodborne Diseases/transmission , HumansABSTRACT
The paper presents the results of 3-year observations of the status of herd immunity to poliomyelitis in 7 towns of the Moscow region. In individual years antibody for poliomyelitis virus of 3 types was found in 63-74% of the examined children and from 2.7 to 7.5% of children were triple-negative. Insufficient levels of herd immunity to poliovirus types I and III were found. Some factors are analysed which could have some influence on the decline of herd immunity.
