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1.
Clin Ter ; 170(1): e7-e10, 2020.
Article in English | MEDLINE | ID: mdl-31850477

ABSTRACT

Whiplash injuries, a common sequel of road traffic accidents, may be defined as a musculo-ligamentous sprain resulting from forced acceleration/deceleration and flexion/ extension neck injury. We report a non-fatal case of vertebral right artery dissection after a minor rear-lateral collision. The injury was detected twenty-four days after trauma when a computerized tomography (CT) scan and cerebral angiography revealed multiple ischemic lesions of the right cerebellum. Digital subtraction angiography (DSA) has been the most sensitive imaging modality to describe the types and degree of vascular injury. The accuracy of such imaging allows linking several injuries with minor car crash avoiding patients seeking litigation for correct financial compensation.


Subject(s)
Cerebrum/diagnostic imaging , Vertebral Artery/surgery , Whiplash Injuries/diagnosis , Whiplash Injuries/surgery , Accidents, Traffic , Adult , Humans , Italy , Male , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
2.
Infection ; 38(4): 301-19, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20514509

ABSTRACT

The objective of this document is to identify and reinforce current recommendations concerning the management of HIV infection in infants and children in the context of good resource availability. All recommendations were graded according to the strength and quality of the evidence and were voted on by the 57 participants attending the first Italian Consensus on Paediatric HIV, held in Siracusa in 2008. Paediatricians and HIV/AIDS care specialists were requested to agree on different statements summarizing key issues in the management of paediatric HIV. The comprehensive approach on preventing mother-to-child transmission (PMTCT) has clearly reduced the number of children acquiring the infection in Italy. Although further reduction of MTCT should be attempted, efforts to personalize intervention to specific cases are now required in order to optimise the treatment and care of HIV-infected children. The prompt initiation of treatment and careful selection of first-line regimen, taking into consideration potency and tolerance, remain central. In addition, opportunistic infection prevention, adherence to treatment, and long-term psychosocial consequences are becoming increasingly relevant in the era of effective antiretroviral combination therapies (ART). The increasing proportion of infected children achieving adulthood highlights the need for multidisciplinary strategies to facilitate transition to adult care and maintain strategies specific to perinatally acquired HIV infection.


Subject(s)
Anti-Retroviral Agents/therapeutic use , HIV Infections/diagnosis , HIV Infections/drug therapy , Adult , Antiretroviral Therapy, Highly Active , Child , Child, Preschool , Disease Management , Disease Progression , Female , HIV Infections/transmission , Humans , Infant , Infant, Newborn , Infectious Disease Transmission, Vertical , Italy , Pregnancy
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