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1.
Radiat Prot Dosimetry ; 170(1-4): 122-6, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27315828

ABSTRACT

Radiation survey instrumentation is adequate for the use around high-energy accelerators if capable to measure the dose arising from neutrons with energies ranging from thermal up to a few gigaelectronvolts. The SmartREM-LINUS is a commercial extended range rem-counter, consisting of a central (3)He-proportional counter surrounded by a spherical moderator made of borated polyethylene with an internal shield made of lead. The dose rate indicated by the SmartREM-LINUS was investigated for two different irradiation conditions. The linearity and the angular dependence of the indicated dose rate were investigated using reference neutron fields produced by (241)AmBe and (252)Cf. Additional measurements were performed in two different workplace fields with a component of neutrons with energies >20 MeV, namely the CERN-EU high-energy reference field and near the beam dump of the SwissFEL injector test facility. The measured dose rates were compared to a commercial rem-counter (WENDI2) and the results of Monte Carlo simulations.


Subject(s)
Particle Accelerators/instrumentation , Radiation Monitoring/methods , Americium/analysis , Beryllium/analysis , Calibration , Californium/analysis , Humans , Lead/chemistry , Linear Models , Monte Carlo Method , Neutrons , Occupational Exposure/analysis , Polyethylene/chemistry , Radiation Dosage , Radiation Dosimeters , Radiation Monitoring/instrumentation , Switzerland , Workplace
4.
Br J Dermatol ; 157(5): 1032-6, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17854365

ABSTRACT

Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL) observed mainly in Sudan and India where it follows treated VL in 50% and 10% of cases, respectively. We report a 46-year-old patient with acquired immune deficiency syndrome who, 7 months after diagnosis of VL, developed PKDL and uveal leishmaniasis following HAART-induced immune recovery. In southern Europe PKDL seems to be an emerging clinical presentation among human immunodeficiency virus (HIV)-infected patients experiencing HAART-induced immune recovery after a previous diagnosis of VL. The best treatment among HIV-infected patients remains to be determined.


Subject(s)
Leishmaniasis, Cutaneous/etiology , Leishmaniasis, Visceral/complications , Acquired Immunodeficiency Syndrome/drug therapy , Americas , Antiprotozoal Agents/therapeutic use , Antiretroviral Therapy, Highly Active , Asia , Humans , Italy/ethnology , Leishmaniasis, Cutaneous/drug therapy , Male , Middle Aged , Pentamidine/therapeutic use , Phosphorylcholine/analogs & derivatives , Phosphorylcholine/therapeutic use , Travel
5.
Radiat Prot Dosimetry ; 122(1-4): 362-6, 2006.
Article in English | MEDLINE | ID: mdl-17151013

ABSTRACT

Human exposure to space radiation implies two kinds of risk, both stochastic and deterministic. Shielding optimisation therefore represents a crucial goal for long-term missions, especially in deep space. In this context, the use of radiation transport codes coupled with anthropomorphic phantoms allows to simulate typical radiation exposures for astronauts behind different shielding, and to calculate doses to different organs. In this work, the FLUKA Monte Carlo code and two phantoms, a mathematical model and a voxel model, were used, taking the Galactic Cosmic Rays (GCR) spectra from the model of Badhwar and O'Neill. The time integral spectral proton fluence of the August 1972 Solar Particle Event (SPE) was represented by an exponential function. For each aluminium shield thickness, besides total doses the contributions from primary and secondary particles for different organs and tissues were calculated separately. More specifically, organ-averaged absorbed doses, dose equivalents and a form of 'biological dose', defined on the basis of initial (clustered) DNA damage, were calculated. As expected, the SPE doses dramatically decreased with increasing shielding, and doses in internal organs were lower than in skin. The contribution of secondary particles to SPE doses was almost negligible; however it is of note that, at high shielding (10 g cm(-2)), most of the secondaries are neutrons. GCR organ doses remained roughly constant with increasing Al shielding. In contrast to SPE results, for the case of cosmic rays, secondary particles accounted for a significant fraction of the total dose.


Subject(s)
Cosmic Radiation/adverse effects , Environmental Exposure/adverse effects , Environmental Exposure/analysis , Models, Biological , Radiation Injuries/etiology , Radiation Injuries/prevention & control , Radiation Protection/methods , Astronauts , Computer Simulation , Dose-Response Relationship, Radiation , Humans , Radiation Dosage , Radiation Protection/instrumentation , Radiation, Ionizing , Risk Assessment/methods , Risk Factors
6.
Br J Sports Med ; 40(8): 730-1; discussion 731, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16723403

ABSTRACT

Adrenal gland haematoma is often a complication of traumatic events. The case is reported of a 45 year old man with unilateral non-symptomatic adrenal gland haematoma caused by a trauma during martial arts practice.


Subject(s)
Adrenal Glands/injuries , Hematoma/diagnosis , Martial Arts/injuries , Hematoma/etiology , Hematoma/surgery , Humans , Male , Middle Aged , Treatment Outcome
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