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Minerva Med ; 72(7): 355-62, 1981 Feb 28.
Article in Italian | MEDLINE | ID: mdl-7017485

ABSTRACT

A single-blind, between-patients trial was run to compare the fluidifying, expectorant, antitussive, antipyretic and anti-inflammatory activity, and the local and systemic tolerance of guacetisal, an active principle obtained by the esterification of acetylsalicylic acid and guaiacol, and oxolamine phosphate, in which the suspension formulation for adults was administered to 30 presenile and senile patients of both sexes with chronic obstructive bronchopathy. A higher activity on the part of guacetisal was noted. The results obtained are illustrated and discussed.


Subject(s)
Aspirin/analogs & derivatives , Lung Diseases, Obstructive/drug therapy , Oxadiazoles/therapeutic use , Aged , Aspirin/pharmacology , Aspirin/therapeutic use , Clinical Trials as Topic , Female , Humans , Male , Middle Aged , Respiration/drug effects
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